Patents by Inventor Hui-Ju Cho

Hui-Ju Cho has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8513405
    Abstract: Disclosed are a chaotropic agent; a reagent including a chaotropic agent and a lithium salt; a reagent kit including a chaotropic agent; a chaotropic agent, a reagent, a reagent kit, and a method for isolating a nucleic acid by use of a magnetic cellulose material; a method for binding a nucleic acid to a magnetic cellulose material; a method for isolating a nucleic acid; and a method for purifying a chromosome DNA. It is required that each of the chaotropic agents, the reagents, and the reagent kits works with at least one solid-phase, magnetic cellulose-containing carrier to isolate a nucleic acid from non-nucleic acid substances. In addition, each chaotropic agent includes an alcohol substance and a substrate solution for adjusting the alcohol substance to an appropriate concentration and thereby promoting binding of the nucleic acid in a sample to the magnetic cellulose.
    Type: Grant
    Filed: April 2, 2008
    Date of Patent: August 20, 2013
    Assignee: RBC Bioscience Corp.
    Inventors: Pei-Shin Jiang, Yu-Ting Su, Kun-Chan Wu, Hui-Ju Cho, Wen-Hsun Kuo, Yuh-Jiuan Lin, Yi-Ling Li, Cheng-Chun Kuan
  • Publication number: 20110166338
    Abstract: Disclosed are a chaotropic agent; a reagent including a chaotropic agent and a lithium salt; a reagent kit including a chaotropic agent; a chaotropic agent, a reagent, a reagent kit, and a method for isolating a nucleic acid by use of a magnetic cellulose material; a method for binding a nucleic acid to a magnetic cellulose material; a method for isolating a nucleic acid; and a method for purifying a chromosome DNA. It is required that each of the chaotropic agents, the reagents, and the reagent kits works with at least one solid-phase, magnetic cellulose-containing carrier to isolate a nucleic acid from non-nucleic acid substances. In addition, each chaotropic agent includes an alcohol substance and a substrate solution for adjusting the alcohol substance to an appropriate concentration and thereby promoting binding of the nucleic acid in a sample to the magnetic cellulose.
    Type: Application
    Filed: April 2, 2008
    Publication date: July 7, 2011
    Inventors: Pei-Shin Jiang, Yu-Ting Su, Kun-Chan Wu, Hui-Ju Cho, Wen-Hsun Kuo, Yuh-Jiuan Lin, Yi-Ling Li, Cheng-Chun Kuan
  • Patent number: 7868145
    Abstract: A magnetic particle and fabrication method thereof. The magnetic particle comprises a polymer core, a magnetic material layer covering the polymer core, and a silicon containing layer covering the magnetic material layer. In addition, the magnetic particle may further comprise a coupling agent on the silicon containing layer, and an active molecule connected to the coupling agent. The magnetic particles provide controllable size, uniform diameter distribution, high magnetization, improved storage stability, and modified surface for targeting biomolecules for biomaterial separation and environmental analysis.
    Type: Grant
    Filed: July 11, 2007
    Date of Patent: January 11, 2011
    Assignee: Industrial Technology Research Institute
    Inventors: Kun Chan Wu, Hui-Ju Cho, Pei-Shin Jiang, Hsiang Yuan Huang, Wen-Hsun Kuo, Chi-Min Chau, Chih Hsien Su, Kun Feng Lee
  • Publication number: 20100204508
    Abstract: A dendritic compound of the following structure: PDn-Z-L is disclosed. In the structure above, P is X—(CH2CH2—O)r—, r is an integer ranging from 1000 to 4000, X is OH, NH2, or OR, R is C1 to C10 alkyl, Dn is a residue of branched C3 to C30 polyol compounds, n is the quantity of layers of the residue of branched compounds and is an integer equal to or greater than 1, L is a metal cation, Z is the residue of a C3 to C30 compound with multi functional groups. The functional groups illustrated above can be carboxylic groups, amino groups, amide groups, or chelating groups. The carboxylic groups, ester groups, amino groups, or amide groups bind to Dn, and the chelating groups bind to the metal cations.
    Type: Application
    Filed: April 26, 2010
    Publication date: August 12, 2010
    Applicant: Industrial Technology Research Institute
    Inventors: Abraham JOSEPHK, Hui-Ju CHO, Yu-Hau SHIH, Chao-Hung KAO, Huang-Chien LIANG
  • Patent number: 7732558
    Abstract: A dendritic compound of the following structure: PDn-Z-L is disclosed. In the structure above, P is X—(CH2CH2—O)r—, r is an integer ranging from 1000 to 4000, X is OH, NH2, or OR, R is C1 to C10alkyl, Dn is a residue of branched C3 to C30 polyol compounds, n is the quantity of layers of the residue of branched compounds and is an integer equal to or greater than 1, L is a metal cation, Z is the residue of a C3 to C30 compound with multi functional groups. The functional groups illustrated above can be carboxylic groups, amino groups, amide groups, or chelating groups. The carboxylic groups, ester groups, amino groups, or amide groups bind to Dn, and the chelating groups bind to the metal cations.
    Type: Grant
    Filed: December 27, 2005
    Date of Patent: June 8, 2010
    Assignee: Industrial Technology Research Institute
    Inventors: Abraham Josephk, Hui-Ju Cho, Yu-Hau Shih, Chao-Hung Kao, Huang-Chien Liang
  • Patent number: 7504082
    Abstract: Magnetic nanoparticles are applicable in imaging, diagnosis, therapy, and biomaterial separation. The magnetic nanoparticles are represented as (FewGdx)vZy, wherein w is from 99.9% to 97.5%, x is from 0.1% to 2.5%, Z is an element of the group VIa, and v, y are positive numbers.
    Type: Grant
    Filed: January 20, 2006
    Date of Patent: March 17, 2009
    Assignee: Industrial Technology Research institute
    Inventors: Hui-Ju Cho, Sheng-Ming Shih, Yuh-Jiuan Lin, Hong-Dun Lin, Kang-Ping Lin
  • Publication number: 20090017518
    Abstract: A magnetic particle and fabrication method thereof. The magnetic particle comprises a polymer core, a magnetic material layer covering the polymer core, and a silicon containing layer covering the magnetic material layer. In addition, the magnetic particle may further comprise a coupling agent on the silicon containing layer, and an active molecule connected to the coupling agent. The magnetic particles provide controllable size, uniform diameter distribution, high magnetization, improved storage stability, and modified surface for targeting biomolecules for biomaterial separation and environmental analysis.
    Type: Application
    Filed: July 11, 2007
    Publication date: January 15, 2009
    Inventors: Kun Chan Wu, Hui-Ju Cho, Pei-Shin Jiang, Hsiang Yuan Huang, Wen-Hsun Kuo, Chi-Min Chau
  • Patent number: 7410811
    Abstract: The present invention relates to an analytical method and device utilizing magnetic materials and acoustics sensor. The invention employs a magnetic material modified with specific recognizable molecules to capture a substance in a sample and provides an external magnetic field to draw the magnetic material to an sensing region of an acoustics sensor, and then converts an effect occurred on a surface of the sensing region to an amount of the substance in the sample, wherein the effect is caused by a contact of the surface with the magnetic material and the substance.
    Type: Grant
    Filed: December 30, 2005
    Date of Patent: August 12, 2008
    Assignee: Industrial Technology Research Institute
    Inventors: Yuh Jiuan Lin, Kun Feng Lee, Chi Min Chau, Hui Ju Cho
  • Patent number: 7396589
    Abstract: Magnetic nanoparticles are applicable in imaging, diagnosis, therapy, and biomaterial separation. The magnetic nanoparticles comprise a core represented as FexMavZy and a shell of an inner-transition element Mb or the compound thereof, wherein Ma is an inner-transition element, Z is an element of the group Vla, x is greater or equal to 0, and v, y are positive numbers. The surface of the shell is optionally modified by liposome, polymer, aliphatic compound, aromatic compound or combinations thereof.
    Type: Grant
    Filed: March 19, 2007
    Date of Patent: July 8, 2008
    Assignee: Industrial Technology Research Institute
    Inventors: Hui-Ju Cho, Sheng-Ming Shih, Yuh-Jiuan Achuan Lin, Hong-Dun Lin, Kang-Ping Lin
  • Publication number: 20070166232
    Abstract: Magnetic nanoparticles are applicable in imaging, diagnosis, therapy, and biomaterial separation. The magnetic nanoparticles comprise a core represented as FexMavZy and a shell of an inner-transition element Mb or the compound thereof, wherein Ma is an inner-transition element, Z is an element of the group Vla, x is greater or equal to 0, and v, y are positive numbers. The surface of the shell is optionally modified by liposome, polymer, aliphatic compound, aromatic compound or combinations thereof.
    Type: Application
    Filed: March 19, 2007
    Publication date: July 19, 2007
    Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Hui-Ju Cho, Sheng-Ming Shih, Yuh-Jiuan Lin, Hong-Dun Lin, Kang-Ping Lin
  • Publication number: 20060286563
    Abstract: The present invention relates to an analytical method and device utilizing magnetic materials and acoustics sensor. The invention employs a magnetic material modified with specific recognizable molecules to capture a substance in a sample and provides an external magnetic field to draw the magnetic material to an sensing region of an acoustics sensor, and then converts an effect occurred on a surface of the sensing region to an amount of the substance in the sample, wherein the effect is caused by a contact of the surface with the magnetic material and the substance.
    Type: Application
    Filed: December 30, 2005
    Publication date: December 21, 2006
    Applicant: Industrial Technology Research
    Inventors: Yuh-Jiuan Lin, Kun-Feng Lee, Chi-Min Chau, Hui-Ju Cho
  • Publication number: 20060165601
    Abstract: A dendritic compound of the following structure: PDn-Z-L is disclosed. In the structure above, P is X—(CH2CH2—O)r—, r is an integer ranging from 1000 to 4000, X is OH, NH2, or OR, R is C1 to C10alkyl, Dn is a residue of branched C3 to C30 polyol compounds, n is the quantity of layers of the residue of branched compounds and is an integer equal to or greater than 1, L is a metal cation, Z is the residue of a C3 to C30 compound with multi functional groups. The functional groups illustrated above can be carboxylic groups, amino groups, amide groups, or chelating groups. The carboxylic groups, ester groups, amino groups, or amide groups bind to Dn, and the chelating groups bind to the metal cations.
    Type: Application
    Filed: December 27, 2005
    Publication date: July 27, 2006
    Applicant: Industrial Technology Research Institute
    Inventors: Abraham Josephk, Hui-Ju Cho, Yu-Hau Shih, Chao-Hung Kao, Huang-Chien Liang
  • Publication number: 20060120964
    Abstract: Magnetic nanoparticles are applicable in imaging, diagnosis, therapy, and biomaterial separation. The magnetic nanoparticles are represented as (FewGdx)Zy, wherein w is from 99.9% to 97.5%, x is from 0.1% to 2.5%, Z is an element of the group VIa, and v, y are positive numbers.
    Type: Application
    Filed: January 20, 2006
    Publication date: June 8, 2006
    Inventors: Hui-Ju Cho, Sheng-Ming Shih, Yuh-Jiuan Lin, Hong-Dun Lin, Kang-Ping Lin
  • Publication number: 20050201941
    Abstract: A magnetic nanoparticle applicable in imaging, diagnosis, therapy and biomaterial separation. The magnetic nanoparticle is characterized as comprising at least an inner-transition element, represented as FexMavZy, wherein Ma is an inner-transition element, Z is an element of the group VIa, x is greater or equal to 0, and both v and y are positive numbers. The magnetic nanoparticle may further comprise a shell to form a core-shell structure, wherein the shell is an inner-transition element Mb or the compound thereof.
    Type: Application
    Filed: May 10, 2005
    Publication date: September 15, 2005
    Inventors: Hui-Ju Cho, Sheng-Ming Shih, Yuh-Jiuan Lin, Hong-Dun Lin, Kang-Ping Lin
  • Publication number: 20050025971
    Abstract: A magnetic nanoparticle applicable in imaging, diagnosis, therapy and biomaterial separation. The magnetic nanoparticle is characterized as comprising at least an inner-transition element, represented as FexMavZy, wherein Ma is an inner-transition element, Z is an element of the group VIa, x is greater or equal to 0, and both v and y are positive numbers. The magnetic nanoparticle may further comprise a shell to form a core-shell structure, wherein the shell is an inner-transition element Mb or the compound thereof.
    Type: Application
    Filed: December 19, 2003
    Publication date: February 3, 2005
    Inventors: Hui-Ju Cho, Sheng-Ming Shih, Yuh-Jiuan Lin, Hong-Dun Lin, Kang-Ping Lin