Patents by Inventor Hui-Ju Liang

Hui-Ju Liang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240148753
    Abstract: The present invention pertains to a method for alleviating atherosclerosis in a subject comprising administrating to said subject a composition or pharmaceutical composition comprising Antcin K.
    Type: Application
    Filed: January 10, 2024
    Publication date: May 9, 2024
    Applicant: ARJIL BIOTECH HOLDING COMPANY LIMITED
    Inventors: Yeh B WU, Jir-Mehng LO, Hui Ju LIANG, Pei-Hsin LIN, Chieh-Hsi WU, Chung-Hsin WU
  • Publication number: 20230346737
    Abstract: The present invention pertains to anti viral compounds. The disclosure includes a method for preventing and/or treating a virus infection through the inhibition of a cysteine protease in a virus and/or a sodium taurocholate cotransporting polypeptide in a cell, particularly SARS-COV-2 and hepatitis B virus (HBV). Also provided includes the composition/pharmaceutical composition for preventing and/or treating a virus infection comprising any of the compounds, pharmaceutically acceptable salt thereof, or its mixture, and the use of the compounds.
    Type: Application
    Filed: August 27, 2021
    Publication date: November 2, 2023
    Applicant: ARJIL BIOTECH HOLDING COMPANY LIMITED
    Inventors: Yeh B WU, Jir-Mehng LO, Cheng HUANG, Hui-Ju LIANG, Pei-Hsin LIN, Hao CHIANG, Wei-Chung CHIOU, Guan-Jhong HUANG
  • Publication number: 20230310369
    Abstract: The present invention pertains to a compound, particularly ovatodiolide, for use in preventing or treating an infection of a virus, including a hepatitis virus, an influenza virus, a herpes simplex virus, an enterovirus, a rotavirus, a dengue virus, a poxvirus, a human immunodeficiency virus, an adenovirus, a coronavirus, an arenavirus, a measles virus, a retrovirus and a norovirus, particularly SARS-COV-2. Also provided are the method for preventing or treating a virus infection using the compound, and the pharmaceutical composition or composition comprising the compound.
    Type: Application
    Filed: July 23, 2021
    Publication date: October 5, 2023
    Applicant: ARJIL BIOTECH HOLDING COMPANY LIMITED
    Inventors: Yeh B. Wu, Jir-Mehng Lo, Hui Ju Liang, Cheng Huang
  • Publication number: 20230201221
    Abstract: The present invention relates to a method of preventing or treating a fibrotic condition, comprising administering an effective amount of composition to a subject in need thereof; wherein the composition comprises triterpenes extracted from Antrodia camphorate or Anisomeles indica.
    Type: Application
    Filed: May 19, 2021
    Publication date: June 29, 2023
    Applicant: ARJIL BIOTECH HOLDING COMPANY LIMITED
    Inventors: Yeh-B WU, Jir-Mehng LO, Hui-Ju LIANG, Pei-Hsin LIN
  • Publication number: 20230190850
    Abstract: The present invention relates to a method of preventing or treating a fibrotic condition, comprising administering an effective amount of composition to a subject in need thereof; wherein the composition comprises triterpenes extracted from Antrodia-camphorate or anisomeles indica.
    Type: Application
    Filed: May 19, 2021
    Publication date: June 22, 2023
    Applicant: ARJIL BIOTECH HOLDING COMPANY LIMITED
    Inventors: Yeh-B WU, Jir-Mehng LO, Hui-Ju LIANG, Pei-Hsin LIN
  • Publication number: 20230041859
    Abstract: The present invention relates to a method of preventing or treating a fibrotic condition, comprising administering an effective amount of composition to a subject in need thereof; wherein the composition comprises triterpenes extracted from Antrodia camphorate or Anisomeles indica.
    Type: Application
    Filed: July 1, 2021
    Publication date: February 9, 2023
    Inventors: Yeh-B WU, Jir-Mehng LO, Hui-Ju LIANG, Pei-Hsin LIN, Kuo-Kuei HUANG
  • Patent number: 11253527
    Abstract: The present invention pertains to a composition for preparing a medicament for preventing and/or treating a virus infection, especially a hepatitis B virus infection and/or a herpes simplex virus, and uses thereof.
    Type: Grant
    Filed: February 25, 2020
    Date of Patent: February 22, 2022
    Assignee: ARJIL BIOTECH HOLDING COMPANY LIMITED
    Inventors: Yeh B Wu, Jir-Mehng Lo, Hui Ju Liang, Pei-Hsin Lin, Cheng Huang
  • Publication number: 20210338690
    Abstract: The present invention pertains to anti-coronaviral compounds. The disclosure includes a method for preventing and/or treating a coronavirus infection through the inhibition of a cysteine protease in a virus, particularly SARS-COV-2. Also provided includes the composition/pharmaceutical composition for preventing and/or treating a coronavirus infection comprising any of the compounds, pharmaceutically acceptable salt thereof, or its mixture, and the use of the compounds.
    Type: Application
    Filed: April 30, 2021
    Publication date: November 4, 2021
    Applicant: ARJIL BIOTECH HOLDING COMPANY LIMITED
    Inventors: Jir-Mehng LO, Cheng HUANG, Yeh B WU, Hui-Ju LIANG, Pei-Hsin LIN, Hao CHIANG, Wei-Chung CHIOU
  • Publication number: 20200330485
    Abstract: The present invention pertains to a method for inhibiting, reducing or reversing atherosclerosis or a composition or pharmaceutical composition for preventing or treating an atherosclerotic disease containing a preparation of Antrodia camphorata, and/or one or more active compounds isolated form Antrodia camphorataa.
    Type: Application
    Filed: April 17, 2020
    Publication date: October 22, 2020
    Applicant: ARJIL BIOTECH HOLDING COMPANY LIMITED
    Inventors: Yeh B Wu, Jir-Mehng Lo, Hui Ju Liang, Pei-Hsin Lin, Chieh-Hsi Wu
  • Publication number: 20200268771
    Abstract: The present invention pertains to a composition for preparing a medicament for preventing and/or treating a virus infection, especially a hepatitis B virus infection and/or a herpes simplex virus, and uses thereof.
    Type: Application
    Filed: February 25, 2020
    Publication date: August 27, 2020
    Applicant: ARJIL BIOTECH HOLDING COMPANY LIMITED
    Inventors: Yeh B Wu, Jir-Mehng Lo, Hui Ju Liang, Pei-Hsin Lin, Cheng Huang
  • Patent number: 10688078
    Abstract: The invention relates to a use of a compound for manufacturing a medicament for treating an allergic disease, wherein the compound is selected from the group consisting of ovatodiolide, 1?-acetoxychavicol acetate, zerumbone and combination thereof. Also provided is a method and a composition for treating an allergic disease.
    Type: Grant
    Filed: July 8, 2019
    Date of Patent: June 23, 2020
    Assignee: ARJIL BIOTECH HOLDING COMPANY LIMITED
    Inventors: Yeh B Wu, Jir-Mehng Lo, Hui Ju Liang, Pei-Hsin Lin
  • Publication number: 20200164010
    Abstract: The present invention provides a method for treating dementia, in particular Alzheimer's disease, with an extract of Antrodia camphorata fruit body, or active ingredients thereof. Also provided is the use of the extract of Antrodia camphorate or active ingredients thereof for manufacturing a medicament for treating dementia, in particular Alzheimer's disease.
    Type: Application
    Filed: November 29, 2019
    Publication date: May 28, 2020
    Applicant: ARJIL BIOTECH HOLDING COMPANY LIMITED
    Inventors: Yeh B WU, Jir-Mehng LO, Hui Ju LIANG, Pei-Hsin LIN, Huey-Jen TSAY
  • Publication number: 20200009110
    Abstract: The invention relates to a use of a compound for manufacturing a medicament for treating an allergic disease, wherein the compound is selected from the group consisting of ovatodiolide, 1?-acetoxychavicol acetate, zerumbone and combination thereof. Also provided is a method and a composition for treating an allergic disease.
    Type: Application
    Filed: July 8, 2019
    Publication date: January 9, 2020
    Applicant: Arjil Biotech Holding Company Limited
    Inventors: YEH B WU, JIR-MEHNG LO, HUI JU LIANG, PEI-HSIN LIN
  • Publication number: 20180353520
    Abstract: The present invention provides a method of treating stroke or reducing nerve injury comprising administering to a subject in need thereof a pharmaceutical composition comprising a therapeutically effective amount of a compound of formula (I) or formula (II) wherein W represents R1 represents R2 represents R3 represents R4 represents and R represent H or alkyl groups of C1-C6.
    Type: Application
    Filed: June 12, 2017
    Publication date: December 13, 2018
    Applicant: Arjil Biotech Holding Company Limited
    Inventors: Yeh B WU, Jir-Mehng LO, Ying Chu SHIH, Hui Ju LIANG
  • Publication number: 20180353521
    Abstract: The disclosure is related to a method for treating stroke or reducing nerve injury, which comprises administering to a subject in need thereof a therapeutically effective amount of a compound isolated and purified from Antrodia camphorata fruiting body by methanol extraction. In particular, the compound is dehydroeburicoic acid, dehydrosulphurenic acid or 4,7-Dimethoxy-5-methyl-1,3-benzodioxole.
    Type: Application
    Filed: June 12, 2018
    Publication date: December 13, 2018
    Applicant: Arjil Biotech Holding Company Limited
    Inventors: Yeh B WU, Jir-Mehng LO, Ying Chu SHIH, Hui Ju LIANG
  • Patent number: 8597693
    Abstract: A pharmaceutical composition with an immunomodulating function is provided, including an extract of Bupleurum obtained by grinding the Bupleurum, adding the ground Bupleurum to a solvent and isolating the extract from the solvent, wherein the Bupleurum comprises Bupleurum krlovianum, Bupleurum longiradiatum, Bupleurum smithii, Bupleurum pusillum, Bupleurum longicaule, Bupleurum salicifolium, Bupleurum scorzonerifolium and Bupleurums with at least one of the nucleotide sequences selected from a group consisting of SEQ ID NOs. 1˜6 and a nucleotide sequence with no more than 1% of the nucleotide sequence divergences of SEQ ID NOs. 1˜6, or combinations thereof.
    Type: Grant
    Filed: July 1, 2010
    Date of Patent: December 3, 2013
    Assignee: Industrial Technology Research Institute
    Inventors: Ying-Chu Shih, Lain-Tze Lee, Bie-Shung Tsai, Jir-Mehng Lo, Tien-Soung Tong, Jenn-Line Sheu, Kuo-Kuei Huang, Ying-Fei Tsai, Yi-Ching Lee, Hui-Ju Liang, Jui-Hung Yen, Cheng-Yu Lee
  • Publication number: 20120003250
    Abstract: A pharmaceutical composition with an immunomodulating function is provided, including an extract of Bupleurum obtained by grinding the Bupleurum, adding the ground Bupleurum to a solvent and isolating the extract from the solvent, wherein the Bupleurum comprises Bupleurum krlovianum, Bupleurum longiradiatum, Bupleurum smithii, Bupleurum pusillum, Bupleurum longicaule, Bupleurum salicifolium, Bupleurum scorzonerifolium and Bupleurums with at least one of the nucleotide sequences selected from a group consisting of SEQ ID NOs. 1˜6 and a nucleotide sequence with no more than 1% of the nucleotide sequence divergences of SEQ ID NOs. 1˜6, or combinations thereof.
    Type: Application
    Filed: July 1, 2010
    Publication date: January 5, 2012
    Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Ying-Chu Shih, Lain-Tze Lee, Bie-Shung Tsai, Jir-Mehng Lo, Tien-Soung Tong, Jenn-Line Sheu, Kuo-Kuei Huang, Ying-Fei Tsai, Yi-Ching Lee, Hui-Ju Liang, Jui-Hung Yen, Cheng-Yu Lee