Patents by Inventor Hui-Ju Liang
Hui-Ju Liang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240148753Abstract: The present invention pertains to a method for alleviating atherosclerosis in a subject comprising administrating to said subject a composition or pharmaceutical composition comprising Antcin K.Type: ApplicationFiled: January 10, 2024Publication date: May 9, 2024Applicant: ARJIL BIOTECH HOLDING COMPANY LIMITEDInventors: Yeh B WU, Jir-Mehng LO, Hui Ju LIANG, Pei-Hsin LIN, Chieh-Hsi WU, Chung-Hsin WU
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Publication number: 20230346737Abstract: The present invention pertains to anti viral compounds. The disclosure includes a method for preventing and/or treating a virus infection through the inhibition of a cysteine protease in a virus and/or a sodium taurocholate cotransporting polypeptide in a cell, particularly SARS-COV-2 and hepatitis B virus (HBV). Also provided includes the composition/pharmaceutical composition for preventing and/or treating a virus infection comprising any of the compounds, pharmaceutically acceptable salt thereof, or its mixture, and the use of the compounds.Type: ApplicationFiled: August 27, 2021Publication date: November 2, 2023Applicant: ARJIL BIOTECH HOLDING COMPANY LIMITEDInventors: Yeh B WU, Jir-Mehng LO, Cheng HUANG, Hui-Ju LIANG, Pei-Hsin LIN, Hao CHIANG, Wei-Chung CHIOU, Guan-Jhong HUANG
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Publication number: 20230310369Abstract: The present invention pertains to a compound, particularly ovatodiolide, for use in preventing or treating an infection of a virus, including a hepatitis virus, an influenza virus, a herpes simplex virus, an enterovirus, a rotavirus, a dengue virus, a poxvirus, a human immunodeficiency virus, an adenovirus, a coronavirus, an arenavirus, a measles virus, a retrovirus and a norovirus, particularly SARS-COV-2. Also provided are the method for preventing or treating a virus infection using the compound, and the pharmaceutical composition or composition comprising the compound.Type: ApplicationFiled: July 23, 2021Publication date: October 5, 2023Applicant: ARJIL BIOTECH HOLDING COMPANY LIMITEDInventors: Yeh B. Wu, Jir-Mehng Lo, Hui Ju Liang, Cheng Huang
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Publication number: 20230201221Abstract: The present invention relates to a method of preventing or treating a fibrotic condition, comprising administering an effective amount of composition to a subject in need thereof; wherein the composition comprises triterpenes extracted from Antrodia camphorate or Anisomeles indica.Type: ApplicationFiled: May 19, 2021Publication date: June 29, 2023Applicant: ARJIL BIOTECH HOLDING COMPANY LIMITEDInventors: Yeh-B WU, Jir-Mehng LO, Hui-Ju LIANG, Pei-Hsin LIN
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Publication number: 20230190850Abstract: The present invention relates to a method of preventing or treating a fibrotic condition, comprising administering an effective amount of composition to a subject in need thereof; wherein the composition comprises triterpenes extracted from Antrodia-camphorate or anisomeles indica.Type: ApplicationFiled: May 19, 2021Publication date: June 22, 2023Applicant: ARJIL BIOTECH HOLDING COMPANY LIMITEDInventors: Yeh-B WU, Jir-Mehng LO, Hui-Ju LIANG, Pei-Hsin LIN
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Publication number: 20230041859Abstract: The present invention relates to a method of preventing or treating a fibrotic condition, comprising administering an effective amount of composition to a subject in need thereof; wherein the composition comprises triterpenes extracted from Antrodia camphorate or Anisomeles indica.Type: ApplicationFiled: July 1, 2021Publication date: February 9, 2023Inventors: Yeh-B WU, Jir-Mehng LO, Hui-Ju LIANG, Pei-Hsin LIN, Kuo-Kuei HUANG
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Patent number: 11253527Abstract: The present invention pertains to a composition for preparing a medicament for preventing and/or treating a virus infection, especially a hepatitis B virus infection and/or a herpes simplex virus, and uses thereof.Type: GrantFiled: February 25, 2020Date of Patent: February 22, 2022Assignee: ARJIL BIOTECH HOLDING COMPANY LIMITEDInventors: Yeh B Wu, Jir-Mehng Lo, Hui Ju Liang, Pei-Hsin Lin, Cheng Huang
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Publication number: 20210338690Abstract: The present invention pertains to anti-coronaviral compounds. The disclosure includes a method for preventing and/or treating a coronavirus infection through the inhibition of a cysteine protease in a virus, particularly SARS-COV-2. Also provided includes the composition/pharmaceutical composition for preventing and/or treating a coronavirus infection comprising any of the compounds, pharmaceutically acceptable salt thereof, or its mixture, and the use of the compounds.Type: ApplicationFiled: April 30, 2021Publication date: November 4, 2021Applicant: ARJIL BIOTECH HOLDING COMPANY LIMITEDInventors: Jir-Mehng LO, Cheng HUANG, Yeh B WU, Hui-Ju LIANG, Pei-Hsin LIN, Hao CHIANG, Wei-Chung CHIOU
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Publication number: 20200330485Abstract: The present invention pertains to a method for inhibiting, reducing or reversing atherosclerosis or a composition or pharmaceutical composition for preventing or treating an atherosclerotic disease containing a preparation of Antrodia camphorata, and/or one or more active compounds isolated form Antrodia camphorataa.Type: ApplicationFiled: April 17, 2020Publication date: October 22, 2020Applicant: ARJIL BIOTECH HOLDING COMPANY LIMITEDInventors: Yeh B Wu, Jir-Mehng Lo, Hui Ju Liang, Pei-Hsin Lin, Chieh-Hsi Wu
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Publication number: 20200268771Abstract: The present invention pertains to a composition for preparing a medicament for preventing and/or treating a virus infection, especially a hepatitis B virus infection and/or a herpes simplex virus, and uses thereof.Type: ApplicationFiled: February 25, 2020Publication date: August 27, 2020Applicant: ARJIL BIOTECH HOLDING COMPANY LIMITEDInventors: Yeh B Wu, Jir-Mehng Lo, Hui Ju Liang, Pei-Hsin Lin, Cheng Huang
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Patent number: 10688078Abstract: The invention relates to a use of a compound for manufacturing a medicament for treating an allergic disease, wherein the compound is selected from the group consisting of ovatodiolide, 1?-acetoxychavicol acetate, zerumbone and combination thereof. Also provided is a method and a composition for treating an allergic disease.Type: GrantFiled: July 8, 2019Date of Patent: June 23, 2020Assignee: ARJIL BIOTECH HOLDING COMPANY LIMITEDInventors: Yeh B Wu, Jir-Mehng Lo, Hui Ju Liang, Pei-Hsin Lin
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Publication number: 20200164010Abstract: The present invention provides a method for treating dementia, in particular Alzheimer's disease, with an extract of Antrodia camphorata fruit body, or active ingredients thereof. Also provided is the use of the extract of Antrodia camphorate or active ingredients thereof for manufacturing a medicament for treating dementia, in particular Alzheimer's disease.Type: ApplicationFiled: November 29, 2019Publication date: May 28, 2020Applicant: ARJIL BIOTECH HOLDING COMPANY LIMITEDInventors: Yeh B WU, Jir-Mehng LO, Hui Ju LIANG, Pei-Hsin LIN, Huey-Jen TSAY
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Publication number: 20200009110Abstract: The invention relates to a use of a compound for manufacturing a medicament for treating an allergic disease, wherein the compound is selected from the group consisting of ovatodiolide, 1?-acetoxychavicol acetate, zerumbone and combination thereof. Also provided is a method and a composition for treating an allergic disease.Type: ApplicationFiled: July 8, 2019Publication date: January 9, 2020Applicant: Arjil Biotech Holding Company LimitedInventors: YEH B WU, JIR-MEHNG LO, HUI JU LIANG, PEI-HSIN LIN
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Publication number: 20180353520Abstract: The present invention provides a method of treating stroke or reducing nerve injury comprising administering to a subject in need thereof a pharmaceutical composition comprising a therapeutically effective amount of a compound of formula (I) or formula (II) wherein W represents R1 represents R2 represents R3 represents R4 represents and R represent H or alkyl groups of C1-C6.Type: ApplicationFiled: June 12, 2017Publication date: December 13, 2018Applicant: Arjil Biotech Holding Company LimitedInventors: Yeh B WU, Jir-Mehng LO, Ying Chu SHIH, Hui Ju LIANG
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Publication number: 20180353521Abstract: The disclosure is related to a method for treating stroke or reducing nerve injury, which comprises administering to a subject in need thereof a therapeutically effective amount of a compound isolated and purified from Antrodia camphorata fruiting body by methanol extraction. In particular, the compound is dehydroeburicoic acid, dehydrosulphurenic acid or 4,7-Dimethoxy-5-methyl-1,3-benzodioxole.Type: ApplicationFiled: June 12, 2018Publication date: December 13, 2018Applicant: Arjil Biotech Holding Company LimitedInventors: Yeh B WU, Jir-Mehng LO, Ying Chu SHIH, Hui Ju LIANG
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Patent number: 8597693Abstract: A pharmaceutical composition with an immunomodulating function is provided, including an extract of Bupleurum obtained by grinding the Bupleurum, adding the ground Bupleurum to a solvent and isolating the extract from the solvent, wherein the Bupleurum comprises Bupleurum krlovianum, Bupleurum longiradiatum, Bupleurum smithii, Bupleurum pusillum, Bupleurum longicaule, Bupleurum salicifolium, Bupleurum scorzonerifolium and Bupleurums with at least one of the nucleotide sequences selected from a group consisting of SEQ ID NOs. 1˜6 and a nucleotide sequence with no more than 1% of the nucleotide sequence divergences of SEQ ID NOs. 1˜6, or combinations thereof.Type: GrantFiled: July 1, 2010Date of Patent: December 3, 2013Assignee: Industrial Technology Research InstituteInventors: Ying-Chu Shih, Lain-Tze Lee, Bie-Shung Tsai, Jir-Mehng Lo, Tien-Soung Tong, Jenn-Line Sheu, Kuo-Kuei Huang, Ying-Fei Tsai, Yi-Ching Lee, Hui-Ju Liang, Jui-Hung Yen, Cheng-Yu Lee
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Publication number: 20120003250Abstract: A pharmaceutical composition with an immunomodulating function is provided, including an extract of Bupleurum obtained by grinding the Bupleurum, adding the ground Bupleurum to a solvent and isolating the extract from the solvent, wherein the Bupleurum comprises Bupleurum krlovianum, Bupleurum longiradiatum, Bupleurum smithii, Bupleurum pusillum, Bupleurum longicaule, Bupleurum salicifolium, Bupleurum scorzonerifolium and Bupleurums with at least one of the nucleotide sequences selected from a group consisting of SEQ ID NOs. 1˜6 and a nucleotide sequence with no more than 1% of the nucleotide sequence divergences of SEQ ID NOs. 1˜6, or combinations thereof.Type: ApplicationFiled: July 1, 2010Publication date: January 5, 2012Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Ying-Chu Shih, Lain-Tze Lee, Bie-Shung Tsai, Jir-Mehng Lo, Tien-Soung Tong, Jenn-Line Sheu, Kuo-Kuei Huang, Ying-Fei Tsai, Yi-Ching Lee, Hui-Ju Liang, Jui-Hung Yen, Cheng-Yu Lee