Patents by Inventor Hui-Ju Yen

Hui-Ju Yen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CATIONIC LIPID-BASED NANOCARRIER AND PREPARATION METHOD AND APPLICATION THEREOF
    Publication number: 20250009679
    Abstract: A method for preparing a cationic lipid-based nanocarrier includes providing an organic solvent and an aqueous solution, adding compositions for forming a lipid-based nanocarrier and at least one kind of cationic polysaccharides respectively into the organic solvent and the aqueous solution according to respective solubility thereof, and flowing the organic solvent and the aqueous solution through a microfluidic device under the control of a micromixer, so as to mix the organic solvent and the aqueous solution in the microfluidic device, thereby obtaining the cationic lipid-based nanocarrier in a single-step process.
    Type: Application
    Filed: December 4, 2023
    Publication date: January 9, 2025
    Inventors: Jenn-Jong Young, Cheng-Cheung Chen, Chuan-Chang Chuang, Yu-Hsiu Chang, Hui-Ju Yen, Xin-An Chen
  • SERS substrate fabrication method and SERS detection method
    Patent number: 11733166
    Abstract: A fabrication method of a SERS substrate includes (a) preparing a hydrophilic membrane; (b) dipping the hydrophilic membrane in an alcohol; (c) immersing the hydrophilic membrane in a chloride ion aqueous solution; and (d) depositing Ag or Au nanoparticles on the hydrophilic membrane by suction filtration to form the SERS substrate. The hydrophilic membrane includes 10˜20 wt % PVDF, PTFE, PC, PES, nylon, or mixtures thereof, 10˜20 wt % PVP, and 0.2˜1.6 wt % PMMA, PHEMA, or mixtures thereof.
    Type: Grant
    Filed: May 13, 2022
    Date of Patent: August 22, 2023
    Assignee: NATIONAL DEFENSE MEDICAL CENTER
    Inventors: Jenn-Jong Young, Cheng-Cheung Chen, Chia-Ying Chin, Xin-An Chen, Hui-Ju Yen, Ying-Chuan Chen, Hsin-Lun Hsieh
  • SERS SUBSTRATE FABRICATION METHOD AND SERS DETECTION METHOD
    Publication number: 20220390376
    Abstract: A fabrication method of a SERS substrate includes (a) preparing a hydrophilic membrane; (b) dipping the hydrophilic membrane in an alcohol; (c) immersing the hydrophilic membrane in a chloride ion aqueous solution; and (d) depositing Ag or Au nanoparticles on the hydrophilic membrane by suction filtration to form the SERS substrate. The hydrophilic membrane includes 10˜20 wt % PVDF, PTFE, PC, PES, nylon, or mixtures thereof, 10˜20 wt % PVP, and 0.2˜1.6 wt % PMMA, PHEMA, or mixtures thereof.
    Type: Application
    Filed: May 13, 2022
    Publication date: December 8, 2022
    Inventors: Jenn-Jong Young, Cheng-Cheung Chen, Chia-Ying Chin, Xin-An Chen, Hui-Ju Yen, Ying-Chuan Chen, Hsin-Lun Hsieh
  • Fucoidan-quaternized chitosan nanoparticles and application thereof
    Patent number: 11135289
    Abstract: The present invention relates to fucoidan-quaternized chitosan nanoparticles, an immunogenic composition containing the fucoidan-quatemized chitosan nanoparticles, and a method of delivering an agent to a cell by the fucoidan-quaternized chitosan nanoparticles.
    Type: Grant
    Filed: April 24, 2019
    Date of Patent: October 5, 2021
    Assignee: NATIONAL DEFENSE MEDICAL CENTER
    Inventors: Jenn-jong Young, Chuan-Chang Chuang, Meng-Hung Tsai, Huey-Fen Shyu, Cheng-cheung Chen, Kuang-ming Cheng, Jyh-Hwa Kau, Hui-Ju Yen, Fwu-Long Mi
  • FUCOIDAN-QUATERNIZED CHITOSAN NANOPARTICLES AND APPLICATION THEREOF
    Publication number: 20200338191
    Abstract: The present invention relates to fucoidan-quaternized chitosan nanoparticles, an immunogenic composition containing the fucoidan-quatemized chitosan nanoparticles, and a method of delivering an agent to a cell by the fucoidan-quaternized chitosan nanoparticles.
    Type: Application
    Filed: April 24, 2019
    Publication date: October 29, 2020
    Inventors: Jenn-jong Young, Chuan-Chang Chuang, Meng-Hung Tsai, Huey-Fen Shyu, Cheng-cheung Chen, Kuang-ming Cheng, Jyh-Hwa Kau, Hui-Ju Yen