Patents by Inventor Hui-Lin Wu

Hui-Lin Wu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Recombinant plasmid and method for expressing hepatitis B viral antigens and virions in vivo
    Patent number: 7452696
    Abstract: Disclosed is a recombinant plasmid for expressing hepatitis B viral antigens in vivo, comprising an adeno-associated virus (AVV) vector and a replication-competent hepatitis B virus genome fragment. Mice hydrodynamically injected with the recombinant plasmid of the present invention show persistent expression of hepatitis B viral antigens for more than 6 months in the hepatocytes, thus a immuno-competent mouse model for persistent expression of hepatitis B antigens and also for human chronic hepatitis B virus infection is established, which can be applied in evaluation and elucidation of mechanism of chronic hepatitis and anti-viral drug discovery research.
    Type: Grant
    Filed: October 27, 2006
    Date of Patent: November 18, 2008
    Assignee: National Taiwan University
    Inventors: Pei-Jer Chen, Li-Rung Huang, Hui-Lin Wu, Ding-Shinn Chen
  • Recombinant Plasmid and Method for Expressing Hepatitis B Viral Antigens and Virions in Vivo
    Publication number: 20080124364
    Abstract: Disclosed is a recombinant plasmid for expressing hepatitis B viral antigens in vivo, comprising an adeno-associated virus (AVV) vector and a replication-competent hepatitis B virus genome fragment. Mice hydrodynamically injected with the recombinant plasmid of the present invention show persistent expression of hepatitis B viral antigens for more than 6 months in the hepatocytes, thus a immuno-competent mouse model for persistent expression of hepatitis B antigens and also for human chronic hepatitis B virus infection is established, which can be applied in evaluation and elucidation of mechanism of chronic hepatitis and anti-viral drug discovery research.
    Type: Application
    Filed: October 27, 2006
    Publication date: May 29, 2008
    Applicant: NATIONAL TAIWAN UNIVERSITY
    Inventors: Pei-Jer Chen, Li-Rung Huang, Hui-Lin Wu, Ding-Shinn Chen