Patents by Inventor Hui Ling Ko

Hui Ling Ko has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ENHANCED CELL BASED SCREENING PLATFORM FOR ANTI-HBV THERAPEUTICS
    Publication number: 20220098682
    Abstract: A cell comprising: a nucleotide sequence encoding a Hepatitis B Virus (HBV) operably linked to a promoter; two nucleotide sequences each encoding an isoform of HNF4?; and a nucleotide sequence encoding a repressor of HBV transcription, wherein said nucleotide sequence is mutated to decrease or silence expression of the repressor.
    Type: Application
    Filed: January 14, 2020
    Publication date: March 31, 2022
    Inventors: Ee Chee Ren, Hui Ling Ko
  • PARP-1 INHIBITORS
    Publication number: 20140315973
    Abstract: We describe a nucleic acid comprising the sequence RNNWCAAA, in which R is independently G or A, N is independently T, C, G or A and W is independently T or A, suitable for the treatment or prevention of hepatitis B or cancer. N at position 3 may be C, A or T, preferably A or T, more preferably T; N at position 2 may be C; W at position 4 may be T; and R at position 1 may be A. The nucleic acid may have the sequence ACATCAAA or ACTTCAAA.
    Type: Application
    Filed: October 7, 2011
    Publication date: October 23, 2014
    Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH
    Inventors: Ee Chee Ren, Hui Ling Ko