Abstract: Disclosed is a zoom lens, including: a lens barrel, a lens group, a linear magnetic driving mechanism, and a locking structure; the lens barrel extends in a front-to-rear direction; the lens group includes at least one mobile group movably provided in the lens barrel along the front-to-rear direction; the linear magnetic driving mechanism is provided in the lens barrel and drivenly connected to the mobile group; and the locking structure includes a locking member and a locking mechanism, the locking member includes a plurality of locking grooves, and the locking mechanism includes: a latch, an electromagnetic driving mechanism and a reset member; the latch is movably provided in a direction approaching and away from each locking groove, the latch has a locking position inserted into the locking groove and an unlocking position separated from the locking groove during a moving stroke.

Abstract: A text translation method is described that includes initially acquiring text. Thereafter, first text is determined in the initial text; and second text is determined according to the first text, where the second text is used for describing the first text. Additionally, initial text is translated to obtain initial translation text, and the second text is translated to obtain description translation text. Thereafter, the initial translation text is updated according to the description translation text to obtain target translation text of the initial text.

Abstract: Provided are a heterocyclic compound and an organic electroluminescent device comprising the same, which relate to the field of organic electroluminescent technologies. The heterocyclic compound has advantages of good film-forming property, good thermal stability, and relatively high glass-transition temperature, and the service life of the device can be prolonged when the heterocyclic compound is applied to an organic layer of the organic electroluminescent device; meanwhile, the structure has a deep HOMO energy level so that holes can be effectively prevented from diffusing from the emissive layer to the electron transport layer and the recombination probability of the holes and electrons in the emissive layer can be effectively improved; and when the heterocyclic compound is applied to the electron transport layer or hole blocking layer, the luminous efficiency of the device can be effectively improved.

Abstract: A module for an electric circuit and method of fabricating the module in which the module includes a substrate including electric circuitry, and a Direct Current (DC) power package arranged for providing DC power to the electric circuitry by being electrically connected to the substrate, the DC power package includes a first DC terminal and a second DC terminal, the second DC terminal being electrically isolated from the first DC terminal, the first DC terminal includes two planar electrical conductors and the second DC terminal includes one planar electrical conductor. The two planar electrical conductors of the first DC terminal and the one planar electrical conductor of the second DC terminal are planarly stacked with gaps between them, so that the one planar electrical conductor of the second DC terminal is sandwiched between the two planar electrical conductors of the first DC terminal reducing stray inductance in the module.

Abstract: The present disclosure relates to the antibodies specific targeting CD142, antibody-drug conjugates, preparations and uses thereof. The antibody or antigen-binding fragment thereof binding to CD142 is covalently linked to a cytotoxic payload through a linker. The antibody or antigen-binding fragment thereof binding to CD142 and the antibody-drug conjugate exhibit cytotoxic effects on tumor cells.

Abstract: Antibodies specific to MUC18 (a.k.a. MCAM or CD146) and uses thereof for therapeutic and diagnostic purposes are provided. Also provided herein are chimeric antigen receptors (CARs) comprising an extracellular antigen-binding fragment that binds MUC18 and immune cells expressing such.

Abstract: The present disclosure provides materials and methods for CUB domain-containing protein 1 (CDCP1)-targeted therapy.

Abstract: Antibodies specific to MUC18 (a.k.a. MCAM or CD146) and antibody-drug conjugates (ADCs) comprising such. Also provided herein are uses the the anti-MUC18 antibodies or ADCs for therapeutic and diagnostic purposes.

Abstract: The integrity of an end-to-end message sent from a source to a destination in a distributed data pipeline is improved by tracking the number of messages sent to and received by each of the intermediate components and sink components of the pipeline as the messages move through the distributed data pipeline.

Abstract: The present invention discloses a production method of enzymatic reaction using adenosine instead of ATP. The method comprises the following steps: (1) adding ATP regeneration enzyme, AK enzyme and adenosine in proportion to carry out an enzymatic reaction in an enzymatic reaction system; (2) separating the ATP regeneration enzyme and AK enzyme by either directly separating ATP regeneration enzyme and AK enzyme immobilized in a reaction tank, or separating free ATP regeneration enzyme and AK enzyme by an ultrafiltration membrane in a filter; and (3) separating and purifying the filtrate of step (2) to obtain a product. The disclosed method provides: greatly reduced industrial production costs; faster reaction rate; stable enzyme recovery system that is energy efficient and environmentally friendly; and capability of reusing the byproducts or collecting them for the production of ATP.

Abstract: A communication method, an apparatus, a UE, and a readable storage medium are disclosed. The communication method includes: after communication of a first Internet Protocol Multimedia Subsystem (IMS) service between a first User Equipment (UE) and a second UE is finished, initiating a session release process by the first UE in a case that a first condition is met, the session release process being used for releasing a first session, and the first session being used for transmitting the first IMS service; and initiating a session establishment process and an IMS registration process after the session release process is completed, the session establishment process being used for establishing a second session, and the second session being used for transmitting a second IMS service.

Abstract: Pre-initialization environments are generated on at least one hardware processor for running incoming applications. Resource usage of resources configured for the pre-initialization environments in running the incoming applications is monitored. Automatic tuning of a pre-initialization environment among the pre-initialization environments is deactivated, responsive to determining based on the resource usage of resources configured for the pre-initialization environment, that the pre-initialization environment is maintaining a threshold level of efficiency. Automatic tuning of the pre-initialization environment among the pre-initialization environments is activated, responsive to determining based on the resource usage of resources configured for the pre-initialization environment, that the pre-initialization environment is overloaded.

Abstract: Provided is a method for preparing fluralaner. The method includes: mixing 4-(5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydro-isoxazol-3-yl)-2-methyl-benzoic acid, a catalyst, an alcohol and an organic solvent to obtain a mixture, and subjecting the mixture to esterification to obtain an esterification solution containing 4-(5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydro-isoxazol-3-yl)-2-methyl-benzoate; and mixing the esterification solution with 2-amino-N-(2,2,2-trifluoroethyl)acetamide to obtain a mixed solution and subjecting the mixed solution to ester decomposition-amidation to obtain the fluralaner.

Abstract: An obstacle-surmounting walking device is provided, and belongs to the technical field of walking devices. The obstacle-surmounting walking device includes a contact wheel, a driving load-bearing wheel, a free climbing wheel, a climbing drive disc, a climbing drive disc driving disengagement leaf, and a driving device. Contact wheel climbing teeth are arranged on contact wheel rim on the contact wheel, and contact wheel spokes of the contact wheel deviates from a center of the contact wheel rim. The driving load-bearing wheel is fixed on a driving wheel axle, and a bottom end of the driving load-bearing wheel is in contact with an inner surface of the contact wheel rim. A bottom end of the free climbing wheel is engaged with the contact wheel climbing teeth, the free climbing wheel can freely rotate around the driving wheel axle.

Abstract: A flexible sensor and a method of detecting biaxial wrist joint motion and a robotic arm are provided; the flexible sensor of detecting biaxial wrist joint motion includes a light-proof sleeve, a protective layer, a strip-shaped transparent conductive hydrogel, a light intensity sensor, a light source, and a resistance detection module; the transparent conductive hydrogel is arranged in an inner cavity of the light-proof sleeve; the protective layer is arranged between an inner side wall of the light-proof sleeve and the transparent conductive hydrogel; the light intensity sensor and the light source are arranged at two ends of the strip-shaped transparent conductive hydrogel, respectively; the resistance detection module is connected to the two ends of the strip-shaped transparent conductive hydrogel; a longitudinal section of the strip-shaped transparent conductive hydrogel is in a form of a rectangle with unequal length and width.

Abstract: Provided is an air-cooled refrigerator with an evaporator at the bottom of a cabinet thereof. The air-cooled refrigerator includes: a cabinet with a bottom liner; a partition cover plate transversely arranged in the bottom liner to divide the bottom liner into a storage space and a cooling chamber below the storage space; a return air cover arranged at the front of the cooling chamber and provided with at least one front return air inlet; and an evaporator, which is in a flat cuboid shape and is mounted in the cooling chamber in a manner of inclining upwards from front to back, where a front portion of a top surface of the evaporator, the partition cover plate and the return air cover define a frost-accommodating space, such that some of the air that enters from the front return air inlet enters the evaporator from the frost-accommodating space.

Abstract: A method for scalable event driven auto-diagnosis systems includes obtaining a data packet configured for transmission across a network from a source address to a destination address. The method includes obtaining a list of changes to the network. The method also includes analyzing, based on a network model, the data packet using a plurality of analyzers. The method includes correlating the list of changes to the network and the analysis of the data packet. The method further includes determining, based on the correlation between the list of changes to the network and the analysis of the data packet, a configuration status of the network. The method also includes reporting the configuration status to a user.

Abstract: The present invention discloses a triazolone compound of formula (I) and pharmaceutical use thereof. Such compounds have a strong agonistic effect on PPAR? and PPAR?, so the compounds or the pharmaceutically acceptable salts, the tautomers, the mesomers, the racemates, the stereoisomers, the metabolites, the metabolic precursors, the prodrugs or the solvates thereof can be applied to the preparation of a PPAR?/? dual agonist for preventing or treating diseases mediated by PPAR? and/or PPAR?.

Abstract: A method for automatically setting addresses suitable for an RS485 system is provided. The RS485 system includes a host device and a plurality of slave devices. The method includes the following stages. The host device confirms that there are no addresses of the slave devices in a database. The slave devices are turned on in sequence. The slave devices calculate their own respective power-on times. The slave device enter an idle state during the period associated with the power-on time. Only one of the slave devices sends the power-on time to the host device when said slave device leaves the idle state. The host device sets the address of said slave device according to the power-on time when said slave device leaves the idle state.