Patents by Inventor Hui-Ping Tsai

Hui-Ping Tsai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230242501
    Abstract: The present invention provides a novel compound for effectively preventing nerve damage and protecting nerves, and a preparation method thereof. Besides, the present invention also provides a pharmaceutical composition comprising the novel compound, and a use of the novel compound for preventing nerve damage and protecting nerves.
    Type: Application
    Filed: January 28, 2022
    Publication date: August 3, 2023
    Inventors: LAIN-TZE LEE, HUI-PING TSAI, YI-WEN LIN, SHU-FEN HUANG, Shih-Hung LIU, Chin-Wei LIU, PI-TSAN HUANG, MEI-HUI CHEN
  • Patent number: 11311592
    Abstract: Disclosed herein is the novel use of use of a Bauhinia spp. extract, which may upregulate neprilysin, induce autophagy, protect neuron from amyloidopathy or tauopathy, and/or promote neurite outgrowth, thus the Bauhinia spp. extract of the present disclosure may be used as a dietary supplement for the prophylaxis or treatment of amyloid related neurodegenerative diseases so as to ameliorate or alleviate symptoms associated with the amyloid related neurodegenerative diseases.
    Type: Grant
    Filed: February 24, 2020
    Date of Patent: April 26, 2022
    Assignees: ACADEMIA SINICA, INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Chang-Jen Huang, Rita P.-Y. Chen, Yung-Feng Liao, Bo-Kai Wu, Po-Ting Chen, Hui-Ping Tsai, Yi-Cheng Cheng, Cheng-Li Fang, Hung-Chi Chien, Tien-Soung Tong, Ting-Shou Chen, Shu-Jiau Chiou
  • Publication number: 20220088002
    Abstract: Disclosed herein is a method against coronavirus infection, which includes administering to a subject in need thereof an effective amount of 6-bromo-2-[1-(2,5-dimethylphenyl)-5-methyl-1H-pyrazol-4-yl]-quinoline-4-carboxylic acid or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: May 28, 2021
    Publication date: March 24, 2022
    Inventors: Jim-Tong HORNG, Wen-Fang TANG, Hui-Ping TSAI, Chung-Fan HSIEH, Chia-Yi LIN, Guan-Hua LIN, Yu-Li CHEN, Po-Shiuan HSIEH, Tien-Yao CHANG, Yu-Hsiu CHANG
  • Publication number: 20220088105
    Abstract: Disclosed herein is a method against coronavirus infection, which includes administering to a subject in need thereof a composition containing a water-extracted product of Perilla frutescens.
    Type: Application
    Filed: March 30, 2021
    Publication date: March 24, 2022
    Inventors: Jim-Tong Horng, Wen-Fang Tang, Hui-Ping Tsai, Tien-Yao Chang, Po-Shiuan Hsieh, Yu-Hsiu Chang, Chung-Fan Hsieh, Chia-Yi Lin, Guan-Hua Lin, Yu-Li Chen
  • Publication number: 20220087974
    Abstract: Disclosed herein is a method against coronavirus infection, which includes administering to a subject in need thereof an effective amount of 8-benzoyl-4-methyl-9-phenyl-furo[2,3-h]chromen-2-one or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: May 28, 2021
    Publication date: March 24, 2022
    Inventors: Jim-Tong HORNG, Wen-Fang TANG, Hui-Ping TSAI, Chung-Fan HSIEH, Chia-Yi LIN, Guan-Hua LIN, Yu-Li CHEN, Po-Shiuan HSIEH, Tien-Yao CHANG, Yu-Hsiu CHANG
  • Patent number: 11124472
    Abstract: The present invention discloses a novel 3-aryl-2-propen-1-one series derivative and the synthesis processes thereof. Besides, the present invention also discloses the series derivative as a pharmaceutical composition and their use for promoting myocardial regeneration.
    Type: Grant
    Filed: April 8, 2019
    Date of Patent: September 21, 2021
    Assignee: GENHEALTH PHARMA CO., LTD.
    Inventors: Lain-Tze Lee, Hui-Ping Tsai, Shu-Fen Huang, Yi-Wen Lin, Pi-Tsan Huang, Ying-Ying Wu, Mei-Hui Chen, Li-Jie Hsu
  • Publication number: 20200317602
    Abstract: The present invention discloses a novel 3-aryl-2-propen-1-one series derivative and the synthesis processes thereof. Besides, the present invention also discloses the series derivative as a pharmaceutical composition and their use for promoting myocardial regeneration.
    Type: Application
    Filed: April 8, 2019
    Publication date: October 8, 2020
    Applicant: GENHEALTH PHARMA CO., LTD.
    Inventors: Lain-Tze LEE, Hui-Ping TSAI, Shu-Fen HUANG, Yi-Wen LIN, Pi-Tsan HUANG, Ying-Ying WU, Mei-Hui CHEN, Li-Jie HSU
  • Publication number: 20200246410
    Abstract: Disclosed herein is the novel use of use of a Bauhinia spp. extract, which may upregulate neprilysin, induce autophagy, protect neuron from amyloidopathy or tauopathy, and/or promote neurite outgrowth, thus the Bauhinia spp. extract of the present disclosure may be used as a dietary supplement for the prophylaxis or treatment of amyloid related neurodegenerative diseases so as to ameliorate or alleviate symptoms associated with the amyloid related neurodegenerative diseases.
    Type: Application
    Filed: February 24, 2020
    Publication date: August 6, 2020
    Inventors: Chang-Jen HUANG, Rita P.-Y. CHEN, Yung-Feng LIAO, Bo-Kai WU, Po-Ting CHEN, Hui-Ping TSAI, Yi-Cheng CHENG, Cheng-Li FANG, Hung-Chi CHIEN, Tien-Soung TONG, Ting-Shou CHEN, Shu-Jiau CHIOU
  • Patent number: 10610557
    Abstract: Disclosed herein is the novel use of use of a Bauhinia spp. extract, which may upregulate neprilysin, induce autophagy, protect neuron from amyloidopathy or tauopathy, and/or promote neurite outgrowth, thus the Bauhinia spp. extract of the present disclosure may be used as a dietary supplement for the prophylaxis or treatment of amyloid related neurodegenerative diseases so as to ameliorate or alleviate symptoms associated with the amyloid related neurodegenerative diseases.
    Type: Grant
    Filed: November 3, 2016
    Date of Patent: April 7, 2020
    Assignees: ACADEMIA SINICA, INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Chang-Jen Huang, Rita P.-Y. Chen, Yung-Feng Liao, Bo-Kai Wu, Po-Ting Chen, Hui-Ping Tsai, Yi-Cheng Cheng, Cheng-Li Fang, Hung-Chi Chien, Tien-Soung Tong, Ting-Shou Chen, Shu-Jiau Chiou
  • Patent number: 10137159
    Abstract: A method for treating liver fibrosis. The method includes administering to a subject suffering from liver fibrosis a pharmaceutically active extract obtained from a Boehmeria species. Also disclosed is a method for regenerating liver tissue and a method for improving a liver function.
    Type: Grant
    Filed: November 22, 2013
    Date of Patent: November 27, 2018
    Assignee: Industrial Technology Research Institute
    Inventors: Lain-Tze Lee, Ying-Chu Shih, Hui-Ping Tsai, Meng-Nan Lin, Wan-Chun Liu
  • Publication number: 20180318371
    Abstract: Disclosed herein is the novel use of use of a Bauhinia spp. extract, which may upregulate neprilysin, induce autophagy, protect neuron from amyloidopathy or tauopathy, and/or promote neurite outgrowth, thus the Bauhinia spp. extract of the present disclosure may be used as a dietary supplement for the prophylaxis or treatment of amyloid related neurodegenerative diseases so as to ameliorate or alleviate symptoms associated with the amyloid related neurodegenerative diseases.
    Type: Application
    Filed: November 3, 2016
    Publication date: November 8, 2018
    Inventors: Chang-Jen HUANG, Rita P.-Y. CHEN, Yung-Feng LIAO, Bo-Kai WU, Po-Ting CHEN, Hui-Ping TSAI, Yi-Cheng CHENG, Cheng-Li FANG, Hung-Chi CHIEN, Tien-Soung TONG, Ting-Shou CHEN, Shu-Jiau CHIOU
  • Patent number: 9289443
    Abstract: A pharmaceutical composition for preventing or treating hepatitis C is provided, including oleanolic acid derivatives as an active ingredient and a pharmaceutically acceptable carrier. A method for preventing or treating hepatitis C in a subject in need thereof is also provided by administering the subject the pharmaceutical composition given above.
    Type: Grant
    Filed: October 26, 2011
    Date of Patent: March 22, 2016
    Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Lain-Tze Lee, Shau-Feng Chang, Zong-Keng Kuo, Hui-Ping Tsai
  • Patent number: 8815221
    Abstract: A composition used for skin whitening includes: an effective amount of spermidine derivative, wherein a structure of the spermidine derivative is shown as Structure (I): where R1-R5 individually includes H, OH, or OCH3 and at least one of R1-R5 is OH, and the spermidine derivative has tyrosinase inhibition activity; and a cosmetically or pharmaceutically acceptable vehicle, wherein the composition used for skin whitening whitens skin.
    Type: Grant
    Filed: August 5, 2010
    Date of Patent: August 26, 2014
    Assignee: Industrial Technology Research Institute
    Inventors: Lain-Tze Lee, Hui-Ping Tsai, Ling-Meei Tsay, Li-Syuan Jian, Chia-Mu Tu
  • Patent number: 8802662
    Abstract: The invention provides an anti-hepatitis C composition including: an effective amount of limonoid compound, wherein the structure of the limonoid compound is shown as Structure (I): where R1 comprises H or OAc and R2 comprises H or COCH(CH3)2; and a pharmaceutically acceptable carrier or salt, and the anti-hepatitis C composition is used for inhibiting hepatitis C virus or treating hepatitis C. The invention also provides a method for treating hepatitis C and a method for preparing a drug for inhibiting hepatitis C viruses or treating hepatitis C.
    Type: Grant
    Filed: October 4, 2009
    Date of Patent: August 12, 2014
    Assignee: Industrial Technology Research Institute
    Inventors: Lain-Tze Lee, Shau-Feng Chang, Hui-Ping Tsai, Zong-Keng Kuo, Chen-Fang Chung
  • Publication number: 20140079818
    Abstract: A method for treating liver fibrosis. The method includes administering to a subject suffering from liver fibrosis a pharmaceutically active extract obtained from a Boehmeria species. Also disclosed is a method for regenerating liver tissue and a method for improving a liver function.
    Type: Application
    Filed: November 22, 2013
    Publication date: March 20, 2014
    Applicant: Industrial Technology Research Institute
    Inventors: Lain-Tze Lee, Ying-Chu Shih, Hui-Ping Tsai, Meng-Nan Lin, Wan-Chun Liu
  • Publication number: 20120164241
    Abstract: A pharmaceutical composition prepared from a Boehmeria species. This composition can be used to improve liver function and treat liver disease, and promoting liver tissue regeneration.
    Type: Application
    Filed: December 27, 2010
    Publication date: June 28, 2012
    Applicant: Industrial Technology Research Institute(ITRI)
    Inventors: Lain-Tze Lee, Ying-Chu Shih, Hui-Ping Tsai, Meng-Nan Lin, Wan-Chun Liu
  • Publication number: 20120165279
    Abstract: A pharmaceutical composition for preventing or treating hepatitis C is provided, including oleanolic acid derivatives as an active ingredient and a pharmaceutically acceptable carrier. A method for preventing or treating hepatitis C in a subject in need thereof is also provided by administering the subject the pharmaceutical composition given above.
    Type: Application
    Filed: October 26, 2011
    Publication date: June 28, 2012
    Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Lain-Tze Lee, Shau-Feng Chang, Zong-Keng Kuo, Hui-Ping Tsai
  • Patent number: 8039076
    Abstract: The invention provides dyes for optical disc recoding media, having the general formula: wherein m, n is independently selected from integers 0-3; X represents oxygen, sulfur, C—R1, or N—R2R3; Y is oxygen or sulfur; each of R1, R2, and R3 can be the same or different; and Z? is a cation. The dyes have a maximum absorption in wavelength of 300-500 nm and can be used in recording layers of high density optical disc recording media.
    Type: Grant
    Filed: December 27, 2006
    Date of Patent: October 18, 2011
    Assignee: Industrial Technology Research Institute
    Inventors: Shin-Shin Wang, Wen-Ping Chu, Chien-Liang Huang, Wen-Yih Liao, Hui-Ping Tsai, Jong-Lieh Yang, An-Tse Lee
  • Publication number: 20110033403
    Abstract: A composition used for skin whitening includes: an effective amount of spermidine derivative, wherein a structure of the spermidine derivative is shown as Structure (I): where R1-R5 individually includes H, OH, or OCH3 and at least one of R1-R5 is OH, and the spermidine derivative has tyrosinase inhibition activity; and a cosmetically or pharmaceutically acceptable vehicle, wherein the composition used for skin whitening whitens skin.
    Type: Application
    Filed: August 5, 2010
    Publication date: February 10, 2011
    Inventors: Lain-Tze LEE, Hui-Ping TSAI, Ling- Meei TSAY, Li-Syuan JIAN, Chia-Mu TU
  • Publication number: 20100317637
    Abstract: The invention provides an anti-hepatitis C composition including: an effective amount of limonoid compound, wherein the structure of the limonoid compound is shown as Structure (I): where R1 comprises H or OAc and R2 comprises H or COCH(CH3)2; and a pharmaceutically acceptable carrier or salt, and the anti-hepatitis C composition is used for inhibiting hepatitis C virus or treating hepatitis C. The invention also provides a method for treating hepatitis C and a method for preparing a drug for inhibiting hepatitis C viruses or treating hepatitis C.
    Type: Application
    Filed: October 4, 2009
    Publication date: December 16, 2010
    Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Lain-Tze LEE, Shau-Feng CHANG, Hui-Ping TSAI, Zong-Keng KUO, Chen-Fang CHUNG