Patents by Inventor Hui Shi

Hui Shi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12274998
    Abstract: The present disclosure provides a three-dimensional alkynyl-containing porous aromatic framework polymer and a preparation method and use thereof. The polymer has a structure represented by Formula I: The preparation method includes: under a protective atmosphere, mixing tetrakis(p-bromophenyl)methane, 1,3,5-triethynyl benzene, a catalyst and an amine solvent, and subjecting to a Sonogashira-Hagihara coupling reaction to obtain the three-dimensional alkynyl-containing porous aromatic framework polymer having the structure represented by Formula I.
    Type: Grant
    Filed: June 13, 2022
    Date of Patent: April 15, 2025
    Assignee: Nanchang Hangkong University
    Inventors: Xubiao Luo, Xuan Ding, Hui Shi, Xin Sheng, Deng You, Mingming Peng, Penghui Shao, Liming Yang
  • Patent number: 12169491
    Abstract: Dynamic plan interpretation may be implemented to perform queries. A query is received at a database system. A plan to perform the query is generated. For at least a portion of the plan to perform the query, a domain-specific language may be applied to interpret and execute the portion of the plan to perform the query using one or more previously compiled executors instead of generating and compiling code to execute the portion of the plan. Returning a result of the query according to the execution of the plan.
    Type: Grant
    Filed: September 28, 2022
    Date of Patent: December 17, 2024
    Assignee: Amazon Technologies, Inc.
    Inventors: Nemanja Boric, Venkatraman Govindaraju, Demala Palliye Gurunnanselage Shermal Ruwantha Fernando, Naresh Chainani, Ippokratis Pandis, Kiran Kumar Chinta, Hui Shi, Hanna Loboda
  • Patent number: 12159154
    Abstract: The technology of this application relates to a memory management method and apparatus. When garbage collection is performed by using the method, stored information about a first reference cycle is first obtained, where the first reference cycle is a cyclic reference formed by a plurality of objects, and the information about the first reference cycle includes the plurality of objects in the first reference cycle and a reference relationship between the plurality of objects. The method further includes determining that a second reference cycle exists, where information about the second reference cycle matches the information about the first reference cycle, and the information about the second reference cycle includes a plurality of objects in the second reference cycle and a reference relationship between the plurality of objects. The method further includes reclaiming memory occupied by the plurality of objects in the second reference cycle.
    Type: Grant
    Filed: September 24, 2021
    Date of Patent: December 3, 2024
    Assignee: HUAWEI TECHNOLOGIES CO., LTD.
    Inventors: Hui Shi, Yang Ding, Kui Zhang, Chengyuan Wang, Chao Wang
  • Publication number: 20240382533
    Abstract: The present disclosure provides use of a human umbilical cord mesenchymal stem cell-derived small extracellular vesicle (hucMSC-sEV) in preparation of a drug for treating type 2 diabetes mellitus (T2DM), and belongs to the technical field of biomedicine. In the present disclosure, experiments have verified that the hucMSC-SEV can effectively reduce blood glucose in a db/db mouse model, improve a morphological disorder of pancreatic islets, and increase a number of ? cells. Moreover, the hucMSC-sEV can also remodel pancreatic ? cells by reversing apoptosis and dedifferentiation of the ? cells. It is confirmed that the hucMSC-sEV is an effective pharmaceutical ingredient that improves pancreatic islet functions, and can effectively ameliorate T2DM, regulate glucose homeostasis, improve a pancreatic islet structure, and increase a quality of the pancreatic islet ? cells, thereby achieving therapeutic effects from a root cause of the disease.
    Type: Application
    Filed: March 9, 2024
    Publication date: November 21, 2024
    Inventors: Hui QIAN, Yuntong SUN, Fengtian SUN, Wenrong XU, Cheng JI, Hui SHI, Zixuan SUN
  • Publication number: 20240382596
    Abstract: The present invention relates to the technical field of medicine, and in particular, relates to a composition of vancomycin aqueous solution. The pharmaceutical composition contains vancomycin or a pharmaceutically acceptable salt thereof, N-methylalanine, and water. The stability of vancomycin in the state of an aqueous solution can be improved by using N-methylalanine.
    Type: Application
    Filed: June 21, 2022
    Publication date: November 21, 2024
    Applicants: HAINAN POLY PHARM. CO., LTD., ZHEJIANG POLY PHARMACEUTICAL CO., LTD.
    Inventors: Yifan ZHU, Minhua FAN, Ping LU, Zhenkun ZHAO, Cangsu XU, Hui SHI, Le SHEN
  • Publication number: 20240376126
    Abstract: Provided is a class of compounds with methyltransferase inhibitory activity. Specifically, provided is a class of compounds with PRMT5 inhibitory activity. The compounds can be used for preparing a pharmaceutical composition for treating PRMT5 activity-related diseases.
    Type: Application
    Filed: January 2, 2024
    Publication date: November 14, 2024
    Inventors: Long WANG, Haiping WU, Yuan MI, Yilin LIU, Xingnian FU, Meng WANG, Hui SHI, Jiannan GUO
  • Patent number: 12123818
    Abstract: The invention discloses a method for correcting differential pressure values of a fire extinguishing agent concentration analyzer in the engine compartment of an aircraft, the analyzer, and a readable storage media thereof. The method includes: correcting theoretical differential pressure values of the analyzer; measuring actual differential pressure values of the analyzer under different pressure; obtaining a series of corrected viscosity coefficients accordingly; obtaining a relation accordingly; setting a corrected model to replace the original model of the analyzer. It is solved for the problem that the noise influence caused by the pressure of flight environment cannot be overcome in the test of extinguishing agent concentration in aircraft engine compartment.
    Type: Grant
    Filed: May 7, 2024
    Date of Patent: October 22, 2024
    Assignee: UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA
    Inventors: Song Lu, Hui Shi, Weitong Ma, Heping Zhang
  • Publication number: 20240339914
    Abstract: A photovoltaic inverter may include a magnetic ring, a leakage current detection winding, a modulation wave circuit, a filter circuit, and a first direct current power supply. The modulation wave circuit includes a first push-pull circuit, a comparator, a second direct current power supply, and a leakage current sampling resistor. The first push-pull circuit includes a first switching transistor and a second switching transistor. The first switching transistor is turned on when the comparator outputs a first level signal. The second switching transistor is turned on when the comparator outputs a second level signal. The comparator outputs a carrier signal. When the leakage current detection winding is in a charging saturation status, a level signal output by the comparator is inverted.
    Type: Application
    Filed: June 19, 2024
    Publication date: October 10, 2024
    Inventors: Tianqi Hu, Hui Shi, Libin Hui, Chengfei Sun, Yufang Xiao
  • Publication number: 20240307409
    Abstract: Provided are an arginine methyltransferase inhibitor and a use thereof. Specifically, provided are a compound that can be used as an I-type PRMT inhibitor, a preparation method therefor, and a use thereof in the treatment of related diseases. The structure of said compound is as represented by formula (I).
    Type: Application
    Filed: May 18, 2022
    Publication date: September 19, 2024
    Inventors: Xingnian FU, Haiping WU, Meng WANG, Yuan MI, Hui SHI, Jiannan GUO
  • Publication number: 20240230719
    Abstract: Provided is an electrical signal sampling device. The electrical signal sampling device includes a pulse signal source, a first sampling module, and a signal delay module. The pulse signal source is configured to generate a pulse signal. The first sampling module is connected to the pulse signal source through a coupler. The coupler is configured to fan-out the pulse signal to generate a test input signal and a sampling incidence signal. The test input signal is input into a tested device from the coupler and then is coupled to form a test output signal. The first sampling module is configured to collect the sampling incidence signal and the test output signal through the coupler. The signal delay module generates N excitation signals through a preset delay.
    Type: Application
    Filed: February 23, 2022
    Publication date: July 11, 2024
    Inventors: Hui SHI, Yue WANG
  • Publication number: 20240223105
    Abstract: This application provides a photovoltaic inverter and a power control method. The photovoltaic inverter includes an inverter circuit, a plurality of voltage conversion circuits, a plurality of acquisition circuits, and a control circuit. The control circuit is configured to: when an input current of the target voltage conversion circuit is greater than or equal to the current threshold of the target voltage conversion circuit, control turn-on or turn-off of the switch in the target voltage conversion circuit to reduce a current or input power of the target voltage conversion circuit. According to this application, when the input current of the target voltage conversion circuit is greater than or equal to the current threshold of the target voltage conversion circuit, the input power of the voltage conversion circuit can be reduced to ensure power supply safety and improve stability and power supply efficiency of the photovoltaic inverter.
    Type: Application
    Filed: July 13, 2023
    Publication date: July 4, 2024
    Inventors: Libin HUI, Hui SHI, Tianqi HU, Xiaojin TAN, Hu CHEN
  • Publication number: 20240133922
    Abstract: Provided is an electrical signal sampling device. The electrical signal sampling device includes a pulse signal source, a first sampling module, and a signal delay module. The pulse signal source is configured to generate a pulse signal. The first sampling module is connected to the pulse signal source through a coupler. The coupler is configured to fan-out the pulse signal to generate a test input signal and a sampling incidence signal. The test input signal is input into a tested device from the coupler and then is coupled to form a test output signal. The first sampling module is configured to collect the sampling incidence signal and the test output signal through the coupler. The signal delay module generates N excitation signals through a preset delay.
    Type: Application
    Filed: February 23, 2022
    Publication date: April 25, 2024
    Inventors: Hui SHI, Yue WANG
  • Publication number: 20240077631
    Abstract: The present disclosure relates to a seismic imaging free gas structure identification method and system, The method includes: acquiring a seismic imaging dataset, and annotating free gas structures in the seismic imaging sample data set to obtain a training dataset; using a generative adversarial network (GAN) to expand the training dataset for network training, wherein the GAN includes a generative network and a discrimination network; conducting domain conversion on original label data of the free gas training samples to obtain annotating labels: training a Bayesian neural network according to the free gas training datasets and labels, to obtain a free gas structure identification model; acquiring actual seismic imaging data of a target work area; and conducting, according to the actual seismic imaging data, identification by using the free gas structure identification model.
    Type: Application
    Filed: January 18, 2023
    Publication date: March 7, 2024
    Applicant: Institute of Geomechanics, Chinese Academy of Geological Sciences
    Inventors: Hao ZHANG, Chongyuan ZHANG, Xingqiang FENG, Hui SHI
  • Patent number: 11899148
    Abstract: The present disclosure relates to a seismic imaging free gas structure identification method and system. The method includes: acquiring a seismic imaging dataset, and annotating free gas structures in the seismic imaging sample data set to obtain a training dataset; using a generative adversarial network (GAN) to expand the training dataset for network training, wherein the GAN includes a generative network and a discrimination network; conducting domain conversion on original label data of the free gas training samples to obtain annotating labels; training a Bayesian neural network according to the free gas training datasets and labels, to obtain a free gas structure identification model; acquiring actual seismic imaging data of a target work area; and conducting, according to the actual seismic imaging data, identification by using the free gas structure identification model.
    Type: Grant
    Filed: January 18, 2023
    Date of Patent: February 13, 2024
    Assignee: Institute of Geomechanics, Chinese Academy of Geological Sciences
    Inventors: Hao Zhang, Chongyuan Zhang, Xingqiang Feng, Hui Shi
  • Publication number: 20230339936
    Abstract: The present invention provides compounds having kinase inhibitory activity. Specifically, the present invention provides compounds having a structure represented by the following formula (II). The compound of the present invention has good inhibitory activity for a variety of kinases (e.g. ALK, AXL, EGFR, and FLT3), and therefore can be used for preparing a pharmaceutical composition for treating kinase activity-related diseases (e.g. acute myeloid leukemia, etc.).
    Type: Application
    Filed: July 22, 2021
    Publication date: October 26, 2023
    Inventors: Haiping WU, Meng WANG, Yuan MI, Xingnian FU, Hui SHI, Jiannan GUO
  • Patent number: 11784309
    Abstract: A lithium cobalt metal oxide powder is disclosed in the present disclosure. The lithium cobalt metal oxide powder has a coating structure. The lithium cobalt metal oxide powder includes a lithium cobalt metal oxide matrix. The lithium cobalt metal oxide powder further includes a Co3O4 coating layer. A general formula of the lithium cobalt metal oxide powder is LiaCo1-x-yMxNyO2·rCo3O4, wherein 0.002<r?0.05, 1?a?1.1, 0<x?0.02, 0?y?0.005, and a<1+3r; M is a doping element; and N is a coating element. A method for making the lithium cobalt metal oxide powder as described above and a method for determining a content of Co3O4 therein are further provided. The material made in the present disclosure has an excellent electrochemical performance.
    Type: Grant
    Filed: April 26, 2018
    Date of Patent: October 10, 2023
    Assignee: BASF SHANSHAN BATTERY MATERIALS CO., LTD.
    Inventors: Yongchang Li, Hong Dong, Xuyao Hu, Hui Shi, Shuang Chen, Xiangkang Jiang, Xu Li, Zhihua Li
  • Publication number: 20230270880
    Abstract: The present disclosure provides a superparamagnetism-modified and neutrophil exosome biomimetic vesicle-based biological preparation for drug delivery, and a preparation method thereof, belonging to the technical field of engineered nanovesicle drug loading systems. The superparamagnetism-modified and neutrophil exosome biomimetic vesicle-based biological preparation for drug delivery prepared by the preparation method acts on tumor cell lines. It is found that the superparamagnetism-modified and neutrophil exosome biomimetic vesicle-based biological preparation for drug delivery can specifically target tumor cells, induce tumor cell apoptosis, and inhibit tumor growth. The biological preparation significantly extends a survival time of mice and improves an efficacy of drugs against cancers.
    Type: Application
    Filed: April 26, 2021
    Publication date: August 31, 2023
    Applicant: JIANGSU UNIVERSITY
    Inventors: Xu ZHANG, Jiahui ZHANG, Cheng JI, Hui SHI, Wenrong XU, Hui QIAN
  • Publication number: 20230234027
    Abstract: The present disclosure provides a three-dimensional alkynyl-containing porous aromatic framework polymer and a preparation method and use thereof. The polymer has a structure represented by Formula I: The preparation method includes: under a protective atmosphere, mixing tetrakis(p-bromophenyl)methane, 1,3,5-triethynyl benzene, a catalyst and an amine solvent, and subjecting to a Sonogashira-Hagihara coupling reaction to obtain the three-dimensional alkynyl-containing porous aromatic framework polymer having the structure represented by Formula I.
    Type: Application
    Filed: June 13, 2022
    Publication date: July 27, 2023
    Inventors: Xubiao Luo, Xuan Ding, Hui Shi, Xin Sheng, Deng You, Mingming Peng, Penghui Shao, Liming Yang
  • Publication number: 20230168035
    Abstract: An energy-saving portable dryer for digestive endoscope is disclosed, including a box and a top cover. The box is a hollow shell structure, and the top cover covers the upper port of the box to form a sealed environment. The upper end of the top cover is provided with a controller to control the operation of the device. The box is internally provided with heating tubes. The box is provided with a water inlet and drainage mechanism. The bottom end of the box is provided with a liquid heater to heat the disinfection solution in the box to generate hot vapor. The top cover and the box are installed and disassembled through a fixed mechanism. The energy-saving portable dryer for digestive endoscope has the characteristics of energy saving and high efficiency. And its effect of disinfection and sterilization is better, which increases the practicability.
    Type: Application
    Filed: January 17, 2023
    Publication date: June 1, 2023
    Applicant: The Second Medical Center?Chinese PLA General Hospital
    Inventors: Ming WANG, Shiping XU, Hui SHI, Hailan ZHU
  • Publication number: 20230068479
    Abstract: The present disclosure discloses a cathode composite material for a lithium-ion battery (LIB), and a preparation method thereof. The cathode composite material for an LIB is composed of a lithium-containing matrix and a three-layer coating layer coated on a surface of the matrix, where the three-layer coating layer includes a lithium-deficient matrix material layer, a lithium-deficient lithium cobalt phosphate (LCP) layer, and a cobalt phosphate layer in sequence from inside to outside. The cathode composite material of the present disclosure can reduce the oxidation of a highly-delithiated cathode material to an electrolyte under high voltage, and has a high energy density.
    Type: Application
    Filed: October 21, 2020
    Publication date: March 2, 2023
    Applicant: BASF Shanshan Battery Materials Co., Ltd.
    Inventors: Hong DONG, Xiangkang JIANG, Hui SHI, Mengqing WANG, Xiaofei BIE, Bo LI, Jin HU