Abstract: The present invention relates to a perforated plate microstructure module, and more particularly, to a perforated plate microstructure module which can be used to deliver a drug into the skin.

Abstract: A microneedle applicator is provided. A microneedle applicator according to an embodiment of the present invention comprises: a microneedle array; an operation member disposed on the upper portion of the microneedle array and operating such that a user applies an external force so as to insert a microneedle into skin; a housing for accommodating the microneedle array and the operation member; a first guide member disposed in at least one position on a lateral portion of the operation member or on a lateral portion of an interworking member of the operation member; and a second guide member which is disposed on the inner surface of the housing in a position corresponding to the first guide member so as to be engaged with the first guide member, and allows the first guide member to slide so as to prevent the microneedle array from rotating or horizontally distorting when the microneedle array uniformly vertically descends due to the external force.

Abstract: A microneedle applicator is provided. A microneedle applicator according to an embodiment of the present invention comprises: a microneedle array; an operation member disposed on the upper portion of the microneedle array and operating such that a user applies an external force so as to insert a microneedle into skin; a housing for accommodating the microneedle array and the operation member; a first guide member disposed in at least one position on a lateral portion of the operation member or on a lateral portion of an interworking member of the operation member; and a second guide member which is disposed on the inner surface of the housing in a position corresponding to the first guide member so as to be engaged with the first guide member, and allows the first guide member to slide so as to prevent the microneedle array from rotating or horizontally distorting when the microneedle array uniformly vertically descends due to the external force.

Abstract: The present invention relates to a microneedle array and a method for manufacturing the same, the microneedle array comprising: a support; and a plurality of microneedles loaded with a solid-phase formulation which protrude from the upper portion of the support, wherein a liquid-phase formulation is applied or added dropwise onto an area of the upper portion of the support in which the microneedles are not formed, or in a case where one or more holes are formed in the support, the liquid-phase formulation is released, through the holes, onto the area of the upper portion of the support in which the microneedles are not formed.

Abstract: The present invention relates to a method of manufacturing a microstructure, including: (a) forming a solid on a substrate; (b) fluidizing the solid by adding a solvent thereto; and (c) shaping the fluidized solid, and a microstructure manufactured using the method.

Abstract: Provided is a rotating assembly. The rotating assembly is for forming a microstructure, and comprises: a rotating body rotatable about a rotary shaft; a first support member installed on the rotating body so as to be spaced apart from the rotational shaft and having a predetermined viscous composition disposed on an outer surface thereof; and a fluid communicating portion for communicating the inside and the outside of the rotating body, wherein when the rotating body rotates, the viscous composition is pulled in a radially outward direction of the rotary shaft, and the pulled viscous composition is cured through the fluid communicating portion, thereby forming a microstructure.

Abstract: The present invention relates to a perforated plate microstructure module, and more particularly, to a perforated plate microstructure module which can be used to deliver a drug into the skin.

Abstract: Provided is a rotating assembly. The rotating assembly is for forming a microstructure, and comprises: a rotating body rotatable about a rotary shaft; a first support member installed on the rotating body so as to be spaced apart from the rotational shaft and having a predetermined viscous composition disposed on an outer surface thereof; and a fluid communicating portion for communicating the inside and the outside of the rotating body, wherein when the rotating body rotates, the viscous composition is pulled in a radially outward direction of the rotary shaft, and the pulled viscous composition is cured through the fluid communicating portion, thereby forming a microstructure.

Abstract: The present invention relates to a microneedle array and a method for manufacturing the same, the microneedle array comprising: a support; and a plurality of microneedles loaded with a solid-phase formulation which protrude from the upper portion of the support, wherein a liquid-phase formulation is applied or added dropwise onto an area of the upper portion of the support in which the microneedles are not formed, or in a case where one or more holes are formed in the support, the liquid-phase formulation is released, through the holes, onto the area of the upper portion of the support in which the microneedles are not formed.

Abstract: The present invention relates to a microcontainer microstructure including a microcontainer film structure having a sharp tip portion and a method of manufacturing the same.

Abstract: The present invention relates to a method for manufacturing a microstructure, the method comprising the steps of: (a) preparing a viscous composition on a lower substrate; and (b) applying centrifugal force to the viscous composition to induce extension of the viscous composition, thereby manufacturing a microstructure. According to the present invention, (i) a microstructure having a micro-unit diameter and sufficient effective length and hardness is provided; (ii) any process that may destroy activation of a drug or cosmetic component, such as high-temperature treatment, organic solvent treatment, etc., is avoided; (iii) loss resulting from contact and separation is reduced; (iv) the limitation of aspect ratio of the manufactured microstructure is overcome; (v) the limitation of yield resulting from flatness is overcome; and (vi) microstructures of various shapes can be manufactured.

Abstract: The present invention relates to a method of manufacturing a microstructure, including: (a) forming a solid on a substrate; (b) fluidizing the solid by adding a solvent thereto; and (c) shaping the fluidized solid, and a microstructure manufactured using the method.

Abstract: A microneedle applicator for infiltrating microneedles into skin and delivering a drug into the skin is disclosed. The microneedle applicator includes an application portion configured to press the microneedles and has, at one side thereof, a curved surface extending in a direction of applying the microneedles to the skin, a coupler having the microneedles disposed toward the skin at one surface thereof and having the other surface thereof at the curved surface, and a presser extending toward the other side of the application portion and configured to provide a pressing force to the application portion. The application portion is rolled on the skin so that the microneedles are sequentially applied to the skin in a longitudinal direction of the curved surface, and the microneedles are detached from the coupler and applied to the skin.

Abstract: The present invention is directed to a method for manufacturing a microstructure, the method comprising: (a) placing a viscous composition on a substrate; and (b) applying negative pressure to the viscous composition to induce an extension of the viscous composition, thereby forming a microstructure, and a microstructure manufactured therefor. According to the present invention, a microstructure can be formed without performing a heat treatment by applying a negative pressure. Consequently, it is possible to mount on a microstructure various materials that are sensitive to heat and easily damaged or degenerated. According to the present invention, a microstructure can be manufactured in a non-contacting manner, that is, without being contacted with conventionally used another structure such as a mold or filler.

Abstract: Disclosed are a microstructure-based drug delivery system comprising a microporous structure and a method for manufacturing the same, and more specifically, a detachable microstructure-based drug delivery system using a microporous structure layer and a method for manufacturing the same, thereby skipping a drying step which is essential for the manufacturing process of the existing biodegradable microneedle, and solving the problem in that the hardness of the microneedle is reduced when the microneedle contains drugs, failing to penetrate the skin. Here, the microstructure is implantable in the body through the insertion into the body and detachment from the microporous structure, and the detachable microstructure can be applied to wrinkled (skin movement) and corrugated parts through a detachment function thereof.

Abstract: Disclosed are a microstructure-based drug delivery system comprising a microporous structure and a method for manufacturing the same, and more specifically, a detachable microstructure-based drug delivery system using a microporous structure layer and a method for manufacturing the same, thereby skipping a drying step which is essential for the manufacturing process of the existing biodegradable microneedle, and solving the problem in that the hardness of the microneedle is reduced when the microneedle contains drugs, failing to penetrate the skin. Here, the microstructure is implantable in the body through the insertion into the body and detachment from the microporous structure, and the detachable microstructure can be applied to wrinkled (skin movement) and corrugated parts through a detachment function thereof.

Abstract: Provided is a structure for transdermal delivery to deliver a material to a body. The structure for transdermal delivery includes a pillar which is a first dermal infiltration part, a microstructure which is connected to an end of one side of the pillar and serves as a second dermal infiltration part. The microstructure includes a body part formed of a biodegradable viscous composition, and a connection part which includes a first contact surface having viscosity generated by a viscous composition to allow the body part to be connected to the pillar and disposed opposite the end of the one side of the pillar.

Abstract: The present invention relates to a microcontainer microstructure including a microcontainer film structure having a sharp tip portion and a method of manufacturing the same.

Abstract: The present invention relates to a method for manufacturing a microstructure, the method comprising the steps of: (a) preparing a viscous composition on a lower substrate; and (b) applying centrifugal force to the viscous composition to induce extension of the viscous composition, thereby manufacturing a microstructure. According to the present invention, (i) a microstructure having a micro-unit diameter and sufficient effective length and hardness is provided; (ii) any process that may destroy activation of a drug or cosmetic component, such as high-temperature treatment, organic solvent treatment, etc., is avoided; (iii) loss resulting from contact and separation is reduced; (iv) the limitation of aspect ratio of the manufactured microstructure is overcome; (v) the limitation of yield resulting from flatness is overcome; and (vi) microstructures of various shapes can be manufactured.

Abstract: Disclosed are a microstructure-based drug delivery system comprising a microporous structure and a method for manufacturing the same, and more specifically, a detachable microstructure-based drug delivery system using a microporous structure layer and a method for manufacturing the same, thereby skipping a drying step which is essential for the manufacturing process of the existing biodegradable microneedle, and solving the problem in that the hardness of the microneedle is reduced when the microneedle contains drugs, failing to penetrate the skin. Here, the microstructure is implantable in the body through the insertion into the body and detachment from the microporous structure, and the detachable microstructure can be applied to wrinkled (skin movement) and corrugated parts through a detachment function thereof.