Abstract: Disclosed is a method for manufacturing a 3D printing structure, the method including: producing a molded body by performing 3D printing on paste including printing powder in a coagulation bath including a hydrogel; hardening the molded body produced in the coagulation bath; and removing the hydrogel in the coagulation bath. A method for manufacturing a 3D printing structure, which is provided according to an aspect of the disclosure, does not require printing of a separate support, and thus it is possible to save time and costs. A post-processing process for removing a support is not required. Thus, a process is further simplified, and there is no risk of damage to a structure.

Abstract: The present invention relates to a composition for preparing an organic-inorganic complex hydrogel and a kit for preparing an organic-inorganic complex hydrogel comprising same, and specifically, to a composition for preparing an organic-inorganic complex hydrogel and a kit for preparing an organic-inorganic complex hydrogel comprising same, comprising: a biocompatible polymer having a photocrosslinkable functional group; and a calcium phosphate-based ceramic powder.

Abstract: A method for producing granules of a uniform size includes preparing an organic member solution, uniformly dispersing an inorganic member in the organic member solution at a weight ratio of 1 to 10 based on an organic member to form an organic-inorganic composite solution, spraying the organic-inorganic composite solution in an electrostatic charge manner, and polymerizing the sprayed organic-inorganic composite solution to form a hydrogel phase. The granules having a uniform size may be mass-produced in a short time and may be produced at a high yield. The method may be applied to a variety of fields, such as a pharmaceutical field, a medical field, a cosmetics field, and a food field and may replace a conventional spray drying method.

Abstract: The present invention relates to a method for manufacturing a support for regenerating core-shell structured hard tissue and a support for regenerating core-shell structured hard tissue manufactured thereby, wherein the support may further comprise bio-functional materials, such as cells, in a core-shell structure. The method for manufacturing a support for regenerating core-shell structured hard tissue according to the present invention has an effect of manufacturing a support for regenerating core-shell structured hard tissue by a method by which a 3-dimensional structure is prepared by a layer manufacturing process through an extrusion container having a double nozzle. In addition, the support can be manufactured at room temperature, thereby having an effect of containing cells or various bio-functional materials.

Abstract: Disclosed is a method for manufacturing a 3D printing structure, the method including: producing a molded body by performing 3D printing on paste including printing powder in a coagulation bath including a hydrogel; hardening the molded body produced in the coagulation bath; and removing the hydrogel in the coagulation bath. A method for manufacturing a 3D printing structure, which is provided according to an aspect of the disclosure, does not require printing of a separate support, and thus it is possible to save time and costs. A post-processing process for removing a support is not required. Thus, a process is further simplified, and there is no risk of damage to a structure.

Abstract: The present invention relates to a 3D printer wherein a printing material is placed and hardened on a transparent film and a 3D printing method using the same. The 3D printer of the present invention is composed of the film supplying part to provide a transparent film; the material supplying part to provide a printing material on the transparent film; the photo-hardening part to solidify the printing material provided onto the transparent film as a designed form; and the film collecting part to collect the transparent film and the remaining printing material after the printing material has been hardened by the photo-hardening part.

Abstract: The present invention is intended to provide a cleaning apparatus for a 3-dimensional (3D) printing structure and a cleaning method for a 3D printing structure. To this end, the present invention provides a cleaning apparatus for a 3D printing structure, the cleaning apparatus including a hygroscopic paper supply part supplying a hygroscopic paper while the wound film-type hygroscopic paper is unwound, a hygroscopic paper collecting part winding and collecting the film-type hygroscopic paper, a film-type hygroscopic paper moving in a direction from the supply part to the collecting part between the supply part and the collecting part according to a mutual operation of the supply part and the collecting part, and a support part disposed on an opposite surface of a hygroscopic paper surface, on which the 3D printing structure is disposed, with respect to the film-type hygroscopic paper, and a cleaning method for a 3D printing structure, and a cleaning method for a 3D printing structure.

Abstract: The present invention relates to a 3D printing device for multiple materials comprising: a material transfer unit comprising at least two lines; a material supply unit to supply at least one type of printing material on each line of the material transfer unit; a thickness control unit to control a thickness of a material supplied by the material supply unit; a 3D printing module to solidify the material controlled with the thickness by the thickness control unit to a predefined shape to solidify the material on one line and to move to the other line so as to solidify the material on the other line; a material processing module to perform washing or drying for the material solidified by the 3D printing module; and a collecting module to collect the printing material unused during the printing.

Abstract: The purpose of the present invention is to provide a method for producing granules of having a uniform size. To this end, the present invention provides a method for producing granules, the method characterized by including preparing an organic member solution, uniformly dispersing an inorganic member in the organic member solution at a weight ratio of 1 to 10 based on an organic member to form an organic-inorganic composite solution, spraying the organic-inorganic composite solution in an electrostatic charge manner, and polymerizing the sprayed organic-inorganic composite solution to form a hydrogel phase. The production method of the present invention has advantages in that granules having a uniform size may be mass-produced in a short time and the granules may be produced at a high yield.

Abstract: The present invention relates to a 3D printing device for multiple materials comprising: a material transfer unit comprising at least two lines; a material supply unit to supply at least one type of printing material on each line of the material transfer unit; a thickness control unit to control a thickness of a material supplied by the material supply unit; a 3D printing module to solidify the material controlled with the thickness by the thickness control unit to a predefined shape to solidify the material on one line and to move to the other line so as to solidify the material on the other line; a material processing module to perform washing or drying for the material solidified by the 3D printing module; and a collecting module to collect the printing material unused during the printing.

Abstract: The present invention relates to a 3D printer wherein a printing material is placed and hardened on a transparent film and a 3D printing method using the same. The 3D printer of the present invention is composed of the film supplying part to provide a transparent film; the material supplying part to provide a printing material on the transparent film; the photo-hardening part to solidify the printing material provided onto the transparent film as a designed form; and the film collecting part to collect the transparent film and the remaining printing material after the printing material has been hardened by the photo-hardening part.

Abstract: A scaffold for hard tissue regeneration comprising an active ingredient for treating osteoporosis and a preparation method thereof. The scaffold for hard tissue regeneration is prepared by the steps of mixing a polyphenol-based natural substance containing Quercetein or Genistein involved in the activation of osteoblasts and osteoclasts and the biofunctional analog thereof with a ceramic scaffold material and molding the mixture at room temperature into a three-dimensional scaffold. The biofunctional material included in the scaffold above may be sustain-released slowly over the long period of time so that the osteoblast activity is directly improved and at the same time the osteoclast activity is suppressed in the course of bone regeneration, to have the effect of improving bone regeneration.

Abstract: The present invention relates to a method for manufacturing a support for regenerating core-shell structured hard tissue and a support for regenerating core-shell structured hard tissue manufactured thereby, wherein the support may further comprise bio-functional materials, such as cells, in a core-shell structure. The method for manufacturing a support for regenerating core-shell structured hard tissue according to the present invention has an effect of manufacturing a support for regenerating core-shell structured hard tissue by a method by which a 3-dimensional structure is prepared by a layer manufacturing process through an extrusion container having a double nozzle. In addition, the support can be manufactured at room temperature, thereby having an effect of containing cells or various bio-functional materials.

Abstract: A scaffold for hard tissue regeneration comprising an active ingredient for treating osteoporosis and a preparation method thereof. The scaffold for hard tissue regeneration is prepared by the steps of mixing a polyphenol-based natural substance containing Quercetein or Genistein involved in the activation of osteoblasts and osteoclasts and the biofunctional analogue thereof with a ceramic scaffold material and molding the mixture at room temperature into a three-dimensional scaffold. The biofunctional material included in the scaffold above may be sustain-released slowly over the long period of time so that the osteoblast activity is directly improved and at the same time the osteoclast activity is suppressed in the course of bone regeneration, to have the effect of improving bone regeneration.

Abstract: Disclosed are porous material having hierarchical pore structure and preparation method thereof. A method of synthesizing a nanoporous material having high functionality as a support for bioactive material is combined with a three-dimensional rapid prototyping technique. Thereby, the porous material of the invention has interconnected pores of respective size regions and uneven surface corresponding to each size region, and thus conditions favorable for adhesion, division, proliferation, movement, and differentiation of cells are provided, thereby exhibiting efficient applications in various fields, in addition to bone fillers, restorative materials, and scaffolds.

Abstract: Disclosed are porous material having hierarchical pore structure and preparation method thereof. A method of synthesizing a nanoporous material having high functionality as a support for bioactive material is combined with a three-dimensional rapid prototyping technique. Thereby, the porous material of the invention has interconnected pores of respective size regions and uneven surface corresponding to each size region, and thus conditions favorable for adhesion, division, proliferation, movement, and differentiation of cells are provided, thereby exhibiting efficient applications in various fields, in addition to bone fillers, restorative materials, and scaffolds.