Patents by Inventor Hui-Ting Chen

Hui-Ting Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240247032
    Abstract: A method for preparing amphiphiles with dendrimeric skeletons by a solid phase linker approach.
    Type: Application
    Filed: August 23, 2021
    Publication date: July 25, 2024
    Applicant: KAOHSIUNG MEDICAL UNIVERSITY
    Inventors: Chai-Lin Kao, Hui-Ting Chen, Vijayasimha Molakaseema, Anand Selvaraj
  • Patent number: 11344548
    Abstract: A method for treating low bone mineral density associated with osteopenia, osteoporosis, and other diseases is disclosed. The method comprises administrating a composition comprising a 3,5-dihydroxypentanoic acid derivative according to Formula I to a mammal. A compound of 3,5-dihydroxypentanoic acid derivative having a structure according to Formula I or Formula II is also disclosed.
    Type: Grant
    Filed: October 8, 2015
    Date of Patent: May 31, 2022
    Assignee: KAOHSIUNG MEDICAL UNIVERSITY
    Inventors: Hui-Ting Chen, Kuang-Chan Hsieh, Chai-Lin Kao, Je-Ken Chang, Mei-Ling Ho
  • Publication number: 20210322411
    Abstract: A method for treating low bone mineral density associated with osteopenia, osteoporosis, and other diseases is disclosed. The method comprises administrating a composition comprising a 3,5-dihydroxypentanoic acid derivative according to Formula I to a mammal. A compound of 3,5-dihydroxypentanoic acid derivative having a structure according to Formula I or Formula II is also disclosed.
    Type: Application
    Filed: October 8, 2015
    Publication date: October 21, 2021
    Applicant: KAOHSIUNG MEDICAL UNIVERSITY
    Inventors: Hui-Ting Chen, Kuang-Chan Hsieh, Chai-Lin Kao, Je-Ken Chang, Mei-Ling Ho
  • Publication number: 20210015967
    Abstract: A method for preparing hyaluronic acid hydrogel microparticles and a use thereof in repairing articular cartilage defects, the method for preparing hyaluronic acid hydrogel microparticles includes: (a) reacting hyaluronic acid with methacrylic anhydride to synthesize a methacrylated hyaluronic acid conjugate; (b) mixing the methacrylated hyaluronic acid conjugate with a photoinitiator, and irradiating ultraviolet light to carry out a photopolymerization reaction so as to obtain a hyaluronic acid hydrogel; and (c) passing the hyaluronic acid hydrogel through a sieve to obtain hyaluronic acid hydrogel microparticles.
    Type: Application
    Filed: March 23, 2018
    Publication date: January 21, 2021
    Applicant: KAOHSIUNG MEDICAL UNIVERSITY
    Inventors: Mei-Ling HO, Je-Ken CHANG, Chung-Hwan CHEN, Hui-Ting CHEN, Shun Cheng WU, Benjamin TEONG
  • Patent number: 9415114
    Abstract: A series of peptides with divergent confirmations including structures of formula (1A), (1B), (2) and (3) are provided. In the formula, wherein U, G, A, B, R1, R2 and T are as defined in the specification. The divergent peptides disclosed in the present invention are characterized in a mineral binding affinity function.
    Type: Grant
    Filed: July 22, 2015
    Date of Patent: August 16, 2016
    Assignee: Kaohsiung Medical University
    Inventors: Hui-Ting Chen, Kuang-Chan Hsieh, Je-Ken Chang, Gwo-Jaw Wang, Yin-Chih Fu, Mei-Ling Ho, Cherng-Chyi Tzeng
  • Patent number: 9314533
    Abstract: A series of peptides with divergent confirmations including structures of formula (1A), (1B), (2) and (3) are provided. In the formula, wherein U, G, A, B, R1, R2 and T are as defined in the specification. The divergent peptides disclosed in the present invention are characterized in a mineral binding affinity function.
    Type: Grant
    Filed: June 27, 2014
    Date of Patent: April 19, 2016
    Assignee: KAOHSIUNG MEDICAL UNIVERSITY
    Inventors: Hui-Ting Chen, Kuang-Chan Hsieh, Je-Ken Chang, Gwo-Jaw Wang, Yin-Chih Fu, Mei-Ling Ho, Cherng-Chyi Tzeng
  • Publication number: 20150320876
    Abstract: A series of peptides with divergent confirmations including structures of formula (1A), (1B), (2) and (3) are provided. In the formula, wherein U, G, A, B, R1, R2 and T are as defined in the specification. The divergent peptides disclosed in the present invention are characterized in a mineral binding affinity function.
    Type: Application
    Filed: July 22, 2015
    Publication date: November 12, 2015
    Applicant: KAOHSIUNG MEDICAL UNIVERSITY
    Inventors: Hui-Ting Chen, Kuang-Chan Hsieh, Je-Ken Chang, Gwo-Jaw Wang, Yin-Chih Fu, Mei-Ling Ho, Cherng-Chyi Tzeng
  • Publication number: 20140377212
    Abstract: A series of peptides with divergent confirmations including structures of formula (1A), (1B), (2) and (3) are provided. In the formula, wherein U, G, A, B, R1, R2 and T are as defined in the specification. The divergent peptides disclosed in the present invention are characterized in a mineral binding affinity function.
    Type: Application
    Filed: June 27, 2014
    Publication date: December 25, 2014
    Applicant: Kaohsiung Medical University
    Inventors: Hui-Ting Chen, Kuang-Chan Hsieh, Je-Ken Chang, Gwo-Jaw Wang, Yin-Chih Fu, Mei-Ling Ho, Cherng-Chyi Tzeng
  • Patent number: 8889828
    Abstract: A series of peptides with divergent confirmations including structures of formula (1A), (1B), (2) and (3) are provided. In the formula, wherein U, G, A, B, R1, R2 and T are as defined in the specification. The divergent peptides disclosed in the present invention are characterized in a mineral binding affinity function.
    Type: Grant
    Filed: October 21, 2011
    Date of Patent: November 18, 2014
    Assignee: Kaohsiung Medical University
    Inventors: Hui-Ting Chen, Kuang-Chan Hsieh, Je-Ken Chang, Gwo-Jaw Wang, Yin-Chih Fu, Mei-Ling Ho, Cherng-Chyi Tzeng
  • Patent number: 8883862
    Abstract: A method for locally controlled release of an effective amount of PTH(1-34) by a hyaluronic acid based hydrogel that can injected intra-articularly for the treatment of osteoarthritis is provided.
    Type: Grant
    Filed: January 12, 2012
    Date of Patent: November 11, 2014
    Assignee: Kaohsiung Medical University
    Inventors: Mei-Ling Ho, Rajalakshmanan Eswaramoorthy, Shun-Cheng Wu, Gwo-Jaw Wang, Je-Ken Chang, Yin-Chih Fu, Cherng-Chyi Tzeng, Hui-Ting Chen, Yao-Hsien Wang
  • Patent number: 8663677
    Abstract: A controlled release system and manufacturing method is provided. The method comprises providing a first aqueous solution containing a hydrophilic drug and an alkaline agent, providing an organic solution containing a hydrophobic molecule, providing a second aqueous solution containing a hydrophilic surfactant, mixing the first hydrophilic solution with the organic solution to form a first emulsion, and mixing the first emulsion with a second aqueous solution to form a second emulsion containing delayed-release microsphere.
    Type: Grant
    Filed: August 12, 2011
    Date of Patent: March 4, 2014
    Assignee: Kaohsiung Medical University
    Inventors: Yin-Chih Fu, Chih-Kuang Wang, Gwo-Jaw Wang, Mei-Ling Ho, Hui-Ting Chen, Je-Ken Chang, Cherng-Chyi Tzeng
  • Patent number: 8614194
    Abstract: The disclosure provides a cell penetrating peptide. The cell penetrating peptide includes an amino acid sequence of Dn, in which D represents an aspartate residue and 2?n?15.
    Type: Grant
    Filed: July 25, 2012
    Date of Patent: December 24, 2013
    Assignee: Kaohsiung Medical University
    Inventors: Hui-Ting Chen, Hsin-Fang Chang, Yan-Hsiung Wang, Chai-Lin Kao
  • Publication number: 20130183349
    Abstract: A method for locally controlled release of an effective amount of PTH(1-34) by a hyaluronic acid based hydrogel that can injected intra-articularly for the treatment of osteoarthritis is provided.
    Type: Application
    Filed: January 12, 2012
    Publication date: July 18, 2013
    Applicant: KAOHSIUNG MEDICAL UNIVERSITY
    Inventors: Mei-Ling Ho, Rajalakshmanan Eswaramoorthy, Shun-Cheng Wu, Gwo-Jaw Wang, Je-Ken Chang, Yin-Chih Fu, Cherng-Chyi Tzeng, Hui-Ting Chen, Yao-Hsien Wang
  • Publication number: 20120270811
    Abstract: A series of peptides with divergent confirmations including structures of formula (1A), (1B), (2) and (3) are provided. In the formula, wherein U, G, A, B, R1, R2 and T are as defined in the specification. The divergent peptides disclosed in the present invention are characterized in a mineral binding affinity function.
    Type: Application
    Filed: October 21, 2011
    Publication date: October 25, 2012
    Applicant: KAOHSIUNG MEDICAL UNIVERSITY
    Inventors: Hui-Ting Chen, Kuang-Chan Hsieh, Je-Ken Chang, Gwo-Jaw Wang, Yin-Chih Fu, Mei-Ling Ho, Cherng-Chyi Tzeng
  • Publication number: 20110312885
    Abstract: A controlled release system and manufacturing method is provided. The method comprises providing a first aqueous solution containing a hydrophilic drug and an alkaline agent, providing an organic solution containing a hydrophobic molecule, providing a second aqueous solution containing a hydrophilic surfactant, mixing the first hydrophilic solution with the organic solution to form a first emulsion, and mixing the first emulsion with a second aqueous solution to form a second emulsion containing delayed-release microsphere.
    Type: Application
    Filed: August 12, 2011
    Publication date: December 22, 2011
    Applicant: Kaohsiung Medical University
    Inventors: Yin-Chih Fu, Chih-Kuang Wang, Gwo-Jaw Wang, Mei-Ling Ho, Hui-Ting Chen, Je-Ken Chang, Cherng-Chyi Tzeng
  • Publication number: 20080220070
    Abstract: A controlled release system and manufacturing method thereof. The method comprises providing a first aqueous solution containing a hydrophilic drug and an alkaline agent, providing an organic solution containing a hydrophobic molecule, providing a second aqueous solution containing a hydrophilic surfactant, mixing the first hydrophilic solution with the organic solution to form a first emulsion, and mixing the first emulsion with a second aqueous solution to form a second emulsion containing delayed-release microsphere.
    Type: Application
    Filed: September 20, 2007
    Publication date: September 11, 2008
    Inventors: Yin-Chih Fu, Chih-Kuang Wang, Gwo-Jaw Wang, Mei-Ling Ho, Hui-Ting Chen, Jen-Ken Chang, Cherng-Chyi Tzeng