Patents by Inventor Hui Ting TOH

Hui Ting TOH has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CO-CRYSTALS OF NURR1-LBD IN COMPLEX WITH A CYCLOPENTENONE PROSTAGLANDIN AND MODULATORS OF NURR1
    Publication number: 20220331271
    Abstract: Co-crystals comprising the Nuclear receptor related 1 protein-ligand binding domain (Nurr1-LBD) and a cyclopentenone prostaglandin are provided. Also provided are methods of identifying or designing Nurr1-modulating ligands and compounds based on the crystal structures described herein as well as the applications of said ligands and compounds as Nurr1 modulators or medicaments.
    Type: Application
    Filed: June 27, 2022
    Publication date: October 20, 2022
    Inventors: Ho Sup YOON, Sreekanth Rajan, Hui Ting Toh, Xuewei Liu, Hui Yao
  • Co-crystals of Nurr1-LBD in complex with a cyclopentenone prostaglandin and modulators of Nurr1
    Patent number: 11406610
    Abstract: Co-crystals comprising the Nuclear receptor related 1 protein-ligand binding domain (Nurr1-LBD) and a cyclopentenone prostaglandin are provided. Also provided are methods of identifying or designing Nurr1-modulating ligands and compounds based on the crystal structures described herein as well as the applications of said ligands and compounds as Nurr1 modulators or medicaments.
    Type: Grant
    Filed: September 20, 2017
    Date of Patent: August 9, 2022
    Assignee: Nanyang Technological University
    Inventors: Ho Sup Yoon, Sreekanth Rajan, Hui Ting Toh, Xuewei Liu, Hui Yao
  • CO-CRYSTALS OF NURR1-LBD IN COMPLEX WITH A CYCLOPENTENONE PROSTAGLANDIN AND MODULATORS OF NURR1
    Publication number: 20200038352
    Abstract: Co-crystals comprising the Nuclear receptor related 1 protein-ligand binding domain (Nurr1-LBD) and a cyclopentenone prostaglandin are provided. Also provided are methods of identifying or designing Nurr1-modulating ligands and compounds based on the crystal structures described herein as well as the applications of said ligands and compounds as Nurr1 modulators or medicaments.
    Type: Application
    Filed: September 20, 2017
    Publication date: February 6, 2020
    Inventors: Ho Sup YOON, Sreekanth RAJAN, Hui Ting TOH, Xuewei LIU, Hui YAO