Patents by Inventor Hui Y. Yang

Hui Y. Yang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for solid phase combinatorial synthesis of integrin inhibitors
    Patent number: 6586187
    Abstract: Compounds of the formula are useful in the treatment of various disorders including, but not limited to, cancer (tumor metathesis, tumorgenesis/tumor growth), angiogenesis (as in cancer, diabetic retinopathy, rheumatoid arthritis), restenosis (following balloon angioplasty or stent implantation), inflammation (as in rheumatoid arthritis, psoriasis), bone diseases (osteopenia induced by bone metastases, immobilization and glucocortocoid treatment, periodontal disease, hyperparathyroidism and rheumatoid arthritis), and as antiviral agents. Novel method of making compounds of formula I are also provided.
    Type: Grant
    Filed: April 13, 2000
    Date of Patent: July 1, 2003
    Assignee: Wyeth
    Inventors: Ariamala Gopalsamy, Hui Y. Yang
  • Methods for the solid phase synthesis of 2-amino-4(H)-quinazolinone derivatives
    Patent number: 6525061
    Abstract: The present invention relates to solid phase synthesis of substituted 2-amino-4(H)-quinazolinone compounds of formula (I): having pharmacological activity, to processes for their preparation, to a combinatorial library and solid phase methods for preparing libraries of the compounds, to utilizing libraries of the compounds for drug discovery, and to pharmaceutical compositions thereof.
    Type: Grant
    Filed: November 10, 2000
    Date of Patent: February 25, 2003
    Assignee: Wyeth
    Inventors: Ariamala Gopalsamy, Hui Y. Yang
  • 6-amino-2,4-dioxo-3,4-dihydro-1,3,5-triazine derivatives and methods for the solid phase synthesis thereof
    Publication number: 20020049320
    Abstract: The present invention relates to substituted 6-amino-2,4-dioxo-3,4-dihydro-1,3,5-triazine compounds of formula (I) 1
    Type: Application
    Filed: April 4, 2001
    Publication date: April 25, 2002
    Applicant: American Cyanamid Company
    Inventors: Ariamala Gopalsamy, Hui Y. Yang