Abstract: The present invention provides a linker for preparing antibody-drug conjugates and antibody-drug conjugates prepared by the linker, as well as use of the antibody-drug conjugates in a medicament for treating tumor. The linker is capable of coupling simultaneously with the thiol group or amino group on the antibody or functional fragment of the antibody, especially it is capable of coupling with 2, 3 or 4 thiol groups on the antibody or functional fragment of the antibody. A coupled product is uniform and structurally stable.

Abstract: Example embodiments of the present disclosure relate to devices, methods, apparatuses and computer readable storage media for dynamic communication configuration for subnetworks. In example embodiments, a device receives, from a plurality of subnetworks, a plurality of received signal strength indications. Then, the device updates, at least in part based on the plurality of received signal strength indications, a plurality of communication configuration models for the plurality of subnetworks. Further, the device transmits, to the plurality of subnetworks, a plurality of sets of parameters associated with the plurality of communication configuration models to enable respective communication configurations to be determined in the plurality of subnetworks.

Abstract: A cerium-zirconium-aluminum-based composite material, a cGPF catalyst and a preparation method thereof are provided. The cerium-zirconium-aluminum-based composite material adopts a stepwise precipitation method, firstly preparing an aluminum-based pre-treated material, then coprecipitating the aluminum-based pre-treated material with zirconium and cerium sol, and finally roasting at high temperature to obtain the cerium-zirconium-aluminum-based composite material. The cerium-zirconium-aluminum-based composite material has better compactness and higher density, and when it is used in cGPF catalyst, it occupies a smaller volume of pores on the catalyst carrier, such that cGPF catalyst has lower back pressure and better ash accumulation resistance, which is beneficial to large-scale application of cGPF catalyst.

Abstract: The present invention discloses an antibody drug conjugate that targets MSLN. The present invention also disclosed a method of making the antibody drug conjugate (ADC). The present invention further discloses a novel MSLN antibody or a functional fragment thereof comprising engineered heavy and light chains.

Abstract: This application discloses a method for Internet key exchange protocol (IKE) authentication using a certificate. The method includes: A first device parses a certificate to obtain signature information in the certificate. The first device fills an AUTH payload field in an IKE identity authentication (AUTH) message based on the signature information in the certificate, where signature information indicated by the AUTH payload field matches the signature information in the certificate. The first device sends the IKE AUTH message to a second device. In the method for Internet key exchange protocol IKE authentication using a certificate provided in this application, the first device may automatically parse the signature information in the certificate, and fill the related field of the IKE AUTH message based on the signature information. Therefore, user configuration is simplified and product usability is improved.

Abstract: One or more devices, systems, methods and/or non-transitory, machine-readable mediums are described herein for specifying one or more events in an augmented reality (AR) environment relative to a real-world (RW) environment. A system can comprise a memory that stores executable components, and a processor, coupled to the memory, that executes or facilitates execution of the executable components. The executable components can comprise a visual component that analyzes captured visual content of a RW environment, an interface component that integrates the visual content of the RW environment with AR content of an AR environment overlaying the RW environment, and a design component that facilitates in-situ placement of the AR content in the AR environment based on the visual content being overlayed, wherein the AR content comprises a specification of an event to be executed in the RW environment that triggers a virtual asset in the AR environment.

Abstract: The present invention provides a linker for preparing antibody-drug conjugates and antibody-drug conjugates prepared by the linker, as well as use of the antibody-drug conjugates in a medicament for treating tumor. The linker is capable of coupling simultaneously with the thiol group or amino group on the antibody or functional fragment of the antibody, especially it is capable of coupling with 2, 3 or 4 thiol groups on the antibody or functional fragment of the antibody. A coupled product is uniform and structurally stable.

Abstract: The present invention discloses an antibody drug conjugate that targets MSLN. The present invention also disclosed a method of making the antibody drug conjugate (ADC). The present invention further discloses a novel MSLN antibody or a functional fragment thereof comprising engineered heavy and light chains.

Abstract: One or more devices, systems, methods and/or non-transitory, machine-readable mediums are described herein for prototyping applications of spatially aware smart objects using augmented reality (AR). In an embodiment, a system can comprise a memory that stores computer-executable components, and a processor that executes the computer-executable components stored in the memory. The computer-executable components comprise a spatial detection component that determines and tracks spatial positions and orientations of one or more objects in association with moving the one or more objects within a real-world environment, and an interface component comprising a visual programming user interface that facilitates prototyping spatial events and corresponding effects associated with the moving of one or more objects based on the relative spatial positions.

Abstract: Separator and electrolyte composites include a porous self-supporting separator film between or adjacent one or two electrolyte films. The electrolyte films may contain a glyme or mixture of glymes, LiX salt and complexing agent, such as PEO. The porous self-supporting separator film may be used dry or wetted with a liquid electrolyte composition. Solid state batteries and electrochemical cells are disclosed that include the described separator and electrolyte composites in combination with an anode and a cathode.

Abstract: Disclosed is a lifting structure for a treadmill, including a first unit mounted at a bottom of a treadmill frame and a second unit rotatably connected to the first unit. The first unit includes first walls and second walls, and the second unit includes a third wall and fourth walls, the third wall abutting against the first walls when the second unit is in a folded state, and the fourth walls abutting against the second walls when the second unit is in an unfolded state.

Abstract: Memory systems and devices (and associated methods) with improved active performance loss (APL) completion detection are described herein. In one embodiment, a memory device comprises nonvolatile memory and logic configured to (i) write a first value to a first location in the nonvolatile memory, (ii) detect a power loss event corresponding to the memory device, and (iii) before powering down the memory device based at least in part on the detected power loss event, write a second value to a second location in the nonvolatile memory different from the first location. The first value and/or the second value can correspond to a current power cycle number of the memory device. After power is subsequently restored to the memory device, the logic can compare the first and second values and proceed with reconstructing the memory device using APL management data when the first value matches the second value.

Abstract: An integrated pressure condensing boiler is provided which relates to the technical field of boilers. The integrated pressure condensing boiler includes a pressure-bearing housing, a heat-exchange furnace arranged in the pressure-bearing housing, a combustion chamber communicating with the heat-exchange furnace and cooling tube groups fixed in the heat-exchange furnace. Heat-exchange medium flows from bottom to top in the pressure-bearing housing and in the cooling tube groups, and exchanges heat with high-temperature flue gas flowing from top to bottom in the heat-exchange furnace, thus achieving a counterflow heat exchanging. The heat-exchange furnace includes a multi-stage heat-exchange chamber with each heat-exchange chamber being cylindrical. The heat-exchange chambers are arranged in sequence from top to bottom to achieve a flue gas diffusing manner that high-temperature flue gas diffuses from center part to periphery and then gathers from periphery to center part.

Abstract: Examples of the disclosure relate to communication methods and apparatuses, an access point, stations and a computer readable medium. An embodiment of the method comprises: determining, at an access point and based on determining that a direct link between stations based sensing procedure is triggered, a first station and a second station associated with the sensing procedure; and transmitting, to at least one of the first station and the second station, a sensing performing request for performing the sensing procedure. In this way, target sensing between non-access-point stations is achieved, such that sensing coverage is extended and a sensing effect is improved.

Abstract: A semiconductor package includes a lead frame, a low side field-effect transistor (FET), a high side FET, a metal clip, and a molding encapsulation. The low side FET is flipped and is attached to a first die paddle of the lead frame. The lead frame comprises one or more voltage input (Vin) leads; a gate lead; one or more switching node (Lx) leads; a first die paddle; a second die paddle; and an end paddle. Each of an exposed bottom surface of the one or more Lx leads is directly connected to an exposed bottom surface of the end paddle. A longitudinal direction of an exposed bottom surface of the gate lead is perpendicular to a longitudinal direction of each of the exposed bottom surface of the one or more Lx leads. An entirely of each of the one or more Vin leads is of the full thickness.

Abstract: A rechargeable lithium-ion battery includes a positive electrode enabling fast charging. A negative electrode has a first active material including Li4Ti5O12. A positive electrode includes a second active material including LiCoO2. The positive electrode further includes a carbon conductive agent and a binder. A weight ratio of the carbon conductive agent to the binder is in a range of about 2:3 to about 3:2.

Abstract: A vibration isolation/damping satellite mount of a chopped carbon fiber reinforced thermoplastic composite material mainly includes two parts, and the two parts are connected through bolts. Considering the limitation of the molding process, the mount configuration is further optimized, and the mount structure is prepared by using the injection molding process. Furthermore, the vibration isolation/damping satellite mount of the chopped carbon fiber reinforced thermoplastic composite material prepared in the present invention can be used for large loads and complex working conditions, and the connectivity, overall strength stability, vibration isolation performance and service life of the mount all meet the design requirements.

Abstract: One or more devices, systems, methods and/or non-transitory, machine-readable mediums are described herein for specifying one or more events in an augmented reality (AR) environment relative to a real-world (RW) environment. A system can comprise a memory that stores executable components, and a processor, coupled to the memory, that executes or facilitates execution of the executable components. The executable components can comprise a visual component that analyzes captured visual content of a RW environment, an interface component that integrates the visual content of the RW environment with AR content of an AR environment overlaying the RW environment, and a design component that facilitates in-situ placement of the AR content in the AR environment based on the visual content being overlayed, wherein the AR content comprises a specification of an event to be executed in the RW environment that triggers a virtual asset in the AR environment.