Patents by Inventor Hui Yu Yang

Hui Yu Yang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DENDRITIC CELL-BASED CANCER VACCINES AND PREPARATION METHOD THEREOF
    Publication number: 20220233603
    Abstract: The present invention is directed to methods for preparing a recombinant cell and a fusion cell for a dendritic cell-based cancer vaccine, wherein the recombinant cell and the fusion cell comprise DNA of a cancer cell. The present invention is also directed to the fusion cells comprising genomic DNA of a tumor cell, a method for fusing human dendritic cells and fibroblast cells, a pharmaceutical composition comprising the fusion cell, and a method of preventing cancer comprising administering to a cancer patient an effective amount of the fusion cells.
    Type: Application
    Filed: May 27, 2019
    Publication date: July 28, 2022
    Inventors: Sadatoshi SAKUMA, Michiyo OSONO, Futoshi ISHIKAWA, Toshiki UOZUMI, Eriko OKA, Hiroki MURATA, Hui Yu YANG
  • Spliceostatin analogs and methods for their preparation
    Patent number: 9764040
    Abstract: The present invention is directed to novel cytotoxic spliceostatin analogs and derivatives, to antibody drug conjugates thereof, and to methods for using the same to treat medical conditions including cancer.
    Type: Grant
    Filed: September 29, 2016
    Date of Patent: September 19, 2017
    Assignee: Pfizer Inc.
    Inventors: Chakrapani Subramanyam, Frank Erich Koehn, Kenneth John Dirico, Alessandra S. Eustaquio, Michael Eric Green, Haiyin He, Min He, Christopher John O'Donnell, Sujiet Puthenveetil, Anokha Ratnayake, Jesse Alexander Teske, Hui Yu Yang
  • SPLICEOSTATIN ANALOGS AND METHOS FOR THEIR PREPARATION
    Publication number: 20170014523
    Abstract: The present invention is directed to novel cytotoxic spliceostatin analogs and derivatives, to antibody drug conjugates thereof, and to methods for using the same to treat medical conditions including cancer.
    Type: Application
    Filed: September 29, 2016
    Publication date: January 19, 2017
    Inventors: Chakrapani SUBRAMANYAM, Frank Erich KOEHN, Kenneth John DIRICO, Alessandra S. EUSTAQUIO, Michael Eric GREEN, Haiyin HE, Min HE, Christopher John O'DONNELL, Sujiet PUTHENVEETIL, Anokha RATNAYAKE, Jesse Alexander TESKE, Hui Yu YANG
  • Spliceostatin analogs and methods for their preparation
    Patent number: 9504669
    Abstract: The present invention is directed to novel cytotoxic spliceostatin analogs and derivatives, to antibody drug conjugates thereof, and to methods for using the same to treat medical conditions including cancer.
    Type: Grant
    Filed: August 5, 2015
    Date of Patent: November 29, 2016
    Assignee: Pfizer Inc.
    Inventors: Chakrapani Subramanyam, Frank Erich Koehn, Kenneth John Dirico, Alessandra S. Eustaquio, Michael Eric Green, Haiyin He, Min He, Christopher John O'Donnell, Sujiet Puthenveetil, Anokha Ratnayake, Jesse Alexander Teske, Hui Yu Yang
  • SPLICEOSTATIN ANALOGS AND METHODS FOR THEIR PREPARATION
    Publication number: 20160022626
    Abstract: The present invention is directed to novel cytotoxic spliceostatin analogs and derivatives, to antibody drug conjugates thereof, and to methods for using the same to treat medical conditions including cancer.
    Type: Application
    Filed: August 5, 2015
    Publication date: January 28, 2016
    Inventors: Chakrapani SUBRAMANYAM, Frank Erich Koehn, Kenneth John Dirico, Alessandra S. Eustaquio, Michael Eric Green, Haiyin He, Min He, Christopher John O'Donnell, Sujiet Puthenveetil, Anokha Ratnayake, Jesse Alexander Teske, Hui Yu Yang
  • Spliceostatin analogs and methods for their preparation
    Patent number: 9169264
    Abstract: The present invention is directed to novel cytotoxic spliceostatin analogs and derivatives, to antibody drug conjugates thereof, and to methods for using the same to treat medical conditions including cancer.
    Type: Grant
    Filed: October 31, 2013
    Date of Patent: October 27, 2015
    Assignee: Pfizer Inc.
    Inventors: Chakrapani Subramanyam, Frank Erich Koehn, Kenneth John Dirico, Alessandra S. Eustaquio, Michael Eric Green, Haiyin He, Min He, Christopher John O'Donnell, Sujiet Puthenveetil, Anokha Ratnayake, Jesse Alexander Teske, Hui Yu Yang
  • SPLICEOSTATIN ANALOGS AND METHODS FOR THEIR PREPARATION
    Publication number: 20140134193
    Abstract: The present invention is directed to novel cytotoxic spliceostatin analogs and derivatives, to antibody drug conjugates thereof, and to methods for using the same to treat medical conditions including cancer.
    Type: Application
    Filed: October 31, 2013
    Publication date: May 15, 2014
    Applicant: PFIZER INC.
    Inventors: Chakrapani SUBRAMANYAM, Frank Erich KOEHN, Kenneth John DIRICO, Alessandra S. EUSTAQUIO, Michael Eric GREEN, Haiyin HE, Min HE, Christopher John O'DONNELL, Sujiet PUTHENVEETIL, Anokha RATNAYAKE, Jesse Alexander TESKE, Hui Yu YANG
  • Antibiotic P175-A and semisynthetic derivatives thereof
    Patent number: 7211417
    Abstract: This invention relates to a new antibiotic designated P175-A, to production of fermentation of Micromonospora echinospora NRRL 30633, to methods for recovery and concentration from the crude solutions, and to a process for purification and to semisynthetic esters and ethers of P175-A.
    Type: Grant
    Filed: April 28, 2004
    Date of Patent: May 1, 2007
    Assignee: Wyeth Holdings Corporation
    Inventors: Haiyin He, Hui Yu Yang, Scott William Luckman, Valerie S. Bernan
  • Antibiotic P175-A and semisynthetic derivatives thereof
    Publication number: 20040220195
    Abstract: This invention relates to a new antibiotic designated P175-A, to production of fermentation of Micromonospora echinospora NRRL 30633, to methods for recovery and concentration from the crude solutions, and to a process for purification and to semisynthetic esters and ethers of P175-A.
    Type: Application
    Filed: April 28, 2004
    Publication date: November 4, 2004
    Applicant: Wyeth Holdings Corporation
    Inventors: Haiyin He, Hui Yu Yang, Scott William Luckman, Valerie S. Bernan