Patents by Inventor Huibert Adriaan Pols

Huibert Adriaan Pols has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Estrogen receptor alleles that are predictive of increased susceptibility to bone fracture
    Publication number: 20050202435
    Abstract: In one aspect, the present invention provides methods of determining susceptibility to bone fracture in a mammalian subject, wherein the methods comprise analyzing nucleic acid molecules obtained from the mammalian subject to determine which of the P, p X, and x alleles of the estrogen receptor ? gene are present, wherein the presence of a haplotype comprising the p and x alleles is indicative of an increased susceptibility to bone fracture. The present invention also provides kits for determining susceptibility to bone fracture in a mammalian subject.
    Type: Application
    Filed: June 19, 2003
    Publication date: September 15, 2005
    Inventors: Andreas Uitterlinden, Johannes Petrus Maria Van Leeuwen, Huibert Adriaan Pols