Patents by Inventor Huichun Zhu

Huichun Zhu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BENZIMIDAZOLE DERIVATIVES
    Publication number: 20120157471
    Abstract: The present invention relates to a compound of formula (I) or a pharmaceutically acceptable salt thereof, wherein R1A, R1B, R1C, R2, R3, R4, R5, RA, RB, RC and X are as defined herein. These novel benzimidazole derivatives are useful in therapy, in particular for treating diseases or conditions mediated by SMO, including the treatment of abnormal cell growth, such as cancer, in mammals. This invention also relates to a method of using such compounds in the treatment of abnormal cell growth in mammals, especially humans, and to pharmaceutical compositions containing such compounds.
    Type: Application
    Filed: August 11, 2010
    Publication date: June 21, 2012
    Applicant: PFIZER INC.
    Inventors: Sajiv Krishnan Nair, Simon Paul Planken, Michael Bruno Plewe, William Francois Vernier, Yi Yang, Huichun Zhu
  • INHIBITORS OF THE HIV INTEGRASE ENZYME
    Publication number: 20100137283
    Abstract: The present invention is directed to compounds of formula (I), and pharmaceutically acceptable salts and solvates thereof, their synthesis, and their use as modulators or inhibitors of the human immunodeficiency virus (“HIV”) integrase enzyme.
    Type: Application
    Filed: February 1, 2010
    Publication date: June 3, 2010
    Inventors: Klaus Ruprecht Dress, Qiyue Hu, Ted William Johnson, Michael Bruno Plewe, Steven Paul Tanis, Huichun Zhu, Junhu Zhang
  • Inhibitors of the HIV integrase enzyme
    Patent number: 7692014
    Abstract: The present invention is directed to compounds of formula (I), and pharmaceutically acceptable salts and solvates thereof, their synthesis, and their use as modulators or inhibitors of the human immunodeficiency virus (“HIV”) integrase enzyme.
    Type: Grant
    Filed: April 25, 2005
    Date of Patent: April 6, 2010
    Assignee: Pfizer, Inc.
    Inventors: Klaus Ruprecht Dress, Qiyue Hu, Ted William Johnson, Michael Bruno Plewe, Steven Paul Tanis, Huichun Zhu, Junhu Zhang
  • INHIBITORS OF THE HIV INTEGRASE ENZYME
    Publication number: 20070099915
    Abstract: The present invention is directed to compounds of formula (I), and pharmaceutically acceptable salts and solvates thereof, their synthesis, and their use as modulators or inhibitors of the human immunodeficiency virus (“HIV”) integrase enzyme.
    Type: Application
    Filed: October 6, 2006
    Publication date: May 3, 2007
    Inventors: Klaus Dress, Ted Johnson, Michael Plewe, Steven Tanis, Huichun Zhu
  • Inhibitors of the HIV integrase enzyme
    Publication number: 20050277661
    Abstract: The present invention is directed to compounds of formula (i), and pharmaceutically acceptable salts and solvates thereof, their synthesis, and their use as modulators or inhibitors of the human immunodeficiency virus (“HIV”) integrase enzyme.
    Type: Application
    Filed: April 25, 2005
    Publication date: December 15, 2005
    Inventors: Klaus Dress, Qiyue Hu, Ted Johnson, Michael Plewe, Steven Tanis, Huichun Zhu, Junhu Zhang