Patents by Inventor Huifang Dong

Huifang Dong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TRANSCRIPTIONAL REGULATORY ELEMENT AND ITS USE IN ENHANCING THE EXPRESSION OF HETEROLOGOUS PROTEIN
    Publication number: 20220127637
    Abstract: Provided is a polynucleotide the polynucleotide can be used as a WXRE transcriptional regulatory element used to increase the protein expression level of a protein expression system. A protein expression vector or a protein expression systems comprising the above-mentioned WXRE transcriptional regulatory element as well as the use thereof are also provided. The use of the WXRE transcriptional regulatory element can increase the expression level of a heterologous protein greatly with its biological activity unchanged.
    Type: Application
    Filed: January 10, 2022
    Publication date: April 28, 2022
    Inventors: Zheng Zhang, Xiaolu Li, Yuchen Zhang, Yarong Li, Huifang Dong, Jill Cai, Weichang Zhou, Chris Chen, Lili Mu, Chuanlong Tang
  • Transcriptional regulatory element and its use in enhancing the expression of heterologous protein
    Patent number: 11254952
    Abstract: Provided is a polynucleotide, the polynucleotide can be used as a WXRE transcriptional regulatory element used to increase the protein expression level of a protein expression system. A protein expression vector or a protein expression system comprising the above-mentioned WXRE transcriptional regulatory element as well as the use thereof are also provided. The use of the WXRE transcriptional regulatory element can increase the expression level of a heterologous protein greatly with its biological activity unchanged.
    Type: Grant
    Filed: August 14, 2019
    Date of Patent: February 22, 2022
    Assignee: WuXi Biologies Ireland Limited
    Inventors: Zheng Zhang, Xiaolu Li, Yuchen Zhang, Yarong Li, Huifang Dong, Jill Cai, Weichang Zhou, Chris Chen, Lili Mu, Chuanlong Tang
  • TRANSCRIPTIONAL REGULATORY ELEMENT AND ITS USE IN ENHANCING THE EXPRESSION OF HETEROLOGOUS PROTEIN
    Publication number: 20210254100
    Abstract: Provided is a polynucleotide, the polynucleotide can be used as a WXRE transcriptional regulatory element used to increase the protein expression level of a protein expression system. A protein expression vector or a protein expression system comprising the above-mentioned WXRE transcriptional regulatory element as well as the use thereof are also provided. The use of the WXRE transcriptional regulatory element can increase the expression level of a heterologous protein greatly with its biological activity unchanged.
    Type: Application
    Filed: August 14, 2019
    Publication date: August 19, 2021
    Inventors: Zheng Zhang, Xiaolu Li, Yuchen Zhang, Yarong Li, Huifang Dong, Jill Cai, Weichang Zhou, Chris Chen, Lili Mu, Chuanlong Tang