Patents by Inventor Huimei ZHENG

Huimei ZHENG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • USE OF CCDC157 GENE AND MUTANT GENES THEREOF AS MOLECULAR MARKERS IN DIAGNOSIS OF MALE INFERTILITY DISEASES
    Publication number: 20230050804
    Abstract: The present application provides use of a CCDC157 gene and mutant genes thereof as molecular markers in diagnosis of male infertility diseases. Experiments have shown that the CCDC157-MIF515 mutant gene/protein causes male infertility, spermatogenesis disorder, sperm dysfunction, reduced sperm count, reduced sperm motility, abnormal sperm morphology, abnormal sperm head, etc. The CCDC157-MIF515 mutant gene/protein of the present application can be used as target genes for diagnosing male infertility. Meanwhile, the expression level of the CCDC157 of CCDC157 gene/protein is significantly reduced in NOA patients and SCOS patients, and the male infertility can be prevented and/or treated by increasing the activity and/or expression of the CCDC157 protein.
    Type: Application
    Filed: July 18, 2022
    Publication date: February 16, 2023
    Inventors: Yongmei XI, Huimei ZHENG, Chen LI, Xiaohang YANG, Jingping LI, Fengbin ZHANG, Zhongyan LIANG, Jinggen WU, Xin YUAN, Jiaru HOU, Xinhai ZHU, Huan DENG