Patents by Inventor Huiping Xu

Huiping Xu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • LPA receptor agonists and antagonists and methods of use
    Publication number: 20050261252
    Abstract: The present invention relates to compounds according to formula (I) as disclosed herein as well as pharmaceutical compositions which include those compounds. Also disclosed are methods of using such compounds, which have activity as agonists or as antagonists of LPA receptors; such methods including inhibiting LPA activity on an LPA receptor, modulating LPA receptor activity, treating cancer, enhancing cell proliferation, and treating a wound.
    Type: Application
    Filed: February 28, 2005
    Publication date: November 24, 2005
    Inventors: Duane Miller, Gabor Tigyi, James Dalton, Vineet Sardar, Don Elrod, Huiping Xu, Daniel Baker, Dean Wang, Karoly Liliom, David Fischer, Tamas Virag, Nora Nusser
  • Haloacetamide and azide substituted compounds and methods of use thereof
    Publication number: 20050137172
    Abstract: The present invention relates to a novel class of anti-cancer compounds, which contain a haloacetamide or azide moiety and are, in one embodiment, alkylating agents. These agents, either alone or in a composition, are useful for treating cancer, preventing cancer, delaying the progression of cancer, treating and/or preventing the recurrence of cancer, suppressing, inhibiting or reducing the incidence of cancer, or inducing apoptosis in a cancer cell.
    Type: Application
    Filed: October 14, 2004
    Publication date: June 23, 2005
    Inventors: James Dalton, Duane Miller, Vipin Nair, Huiping Xu
  • Haloacetamide and azide substituted compounds and methods of use thereof
    Publication number: 20050085449
    Abstract: The present invention relates to a novel class of anti-cancer compounds, which contain a haloacetamide or azide moiety and are, in one embodiment, alkylating agents. These agents, either alone or in a composition, are useful for treating cancer, preventing cancer, delaying the progression of cancer, treating and/or preventing the recurrence of cancer, suppressing, inhibiting or reducing the incidence of cancer, or inducing apoptosis in a cancer cell.
    Type: Application
    Filed: October 15, 2003
    Publication date: April 21, 2005
    Inventors: James Dalton, Duane Miller, Huiping Xu, Vipin Nair
  • LPA receptor agonists and antagonists and methods of use
    Patent number: 6875757
    Abstract: The present invention relates to compounds according to formula (I) as disclosed herein as well as pharmaceutical compositions which include those compounds. Also disclosed are methods of using such compounds, which have activity as agonists or as antagonists of LPA receptors; such methods including inhibiting LPA activity on an LPA receptor, modulating LPA receptor activity, treating cancer, enhancing cell proliferation, and treating a wound.
    Type: Grant
    Filed: March 19, 2001
    Date of Patent: April 5, 2005
    Assignee: University of Tennessee Research Foundation
    Inventors: Duane D. Miller, Gabor Tigyi, James T. Dalton, Vineet M. Sardar, Don B. Elrod, Huiping Xu, Daniel L. Baker, Dean Wang, Karoly Liliom, David J. Fischer, Tamas Virag, Nora Nusser
  • Haloacetamide and azide substituted compounds and methods of use thereof
    Publication number: 20040167103
    Abstract: The present invention relates to a novel class of androgen receptor targeting agents (ARTA), which contain a haloacetamide or azide moiety and are alkylating agents.
    Type: Application
    Filed: July 10, 2003
    Publication date: August 26, 2004
    Inventors: James T. Dalton, Duane D. Miller, Huiping Xu, Vipin Nair
  • LPA receptor agonists and antagonists and methods of use
    Publication number: 20030130237
    Abstract: The present invention relates to compounds according to formula (I) as disclosed herein as well as pharmaceutical compositions which include those compounds. Also disclosed are methods of using such compounds, which have activity as agonists or as antagonists of LPA receptors; such methods including inhibiting LPA activity on an LPA receptor, modulating LPA receptor activity, treating cancer, enhancing cell proliferation, treating a wound, treating apoptosis or preserving or restoring function in a cell, tissue, or organ, culturing cells, preserving organ or tissue function, and treating a dermatological condition.
    Type: Application
    Filed: September 18, 2001
    Publication date: July 10, 2003
    Inventors: Duane D. Miller, Gabor Tigyi, James T. Dalton, Vineet M. Sardar, Don B. Elrod, Huiping Xu, Daniel L. Baker, Dean Wang, Karoly Liliom, David J. Fischer, Tamas Virag, Nora Nusser
  • LPA receptor agonists and antagonists and methods of use
    Publication number: 20030027800
    Abstract: The present invention relates to compounds according to formula (I) as disclosed herein as well as pharmaceutical compositions which include those compounds. Also disclosed are methods of using such compounds, which have activity as agonists or as antagonists of LPA receptors; such methods including inhibiting LPA activity on an LPA receptor, modulating LPA receptor activity, treating cancer, enhancing cell proliferation, and treating a wound.
    Type: Application
    Filed: March 19, 2001
    Publication date: February 6, 2003
    Inventors: Duane D. Miller, Gabor Tigyi, James T. Dalton, Vineet M. Sardar, Don B. Elrod, Huiping Xu, Daniel L. Baker, Dean Wang, Karoly Liliom, David J. Fischer, Tamas Virag, Nora Nusser