Patents by Inventor Huiru Wang
Huiru Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240239829Abstract: Provided are compositions or products comprising analogs or derivatives of N-acetylneuraminic acid with a particular pH range. The compositions or products are effective for treating or preventing highly pathogenic viral infections such as COVID-19 infection, the serious adverse reactions of vaccines, and infection-relating autoimmune diseases including COVID-19 long haulers. More specifically, the present disclosure relates to the methods of preparing the compositions or the products. Products can be implemented as a therapeutic product, a nutritional supplement, a food, a feed, a food additive, a feed additive, a rehydration salt, or a rehydration solution.Type: ApplicationFiled: April 15, 2022Publication date: July 18, 2024Applicant: B & H Biotechnologies, LLCInventor: Huiru WANG
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Publication number: 20240238410Abstract: The invention provides safer vaccines that induce less adverse reactions particular the serious adverse reactions in a host. Also provided are compositions including these safer vaccines, as well as polynucleotides, vectors, host cells, methods, and kits related thereto. Further provided are methods and kits for preventing or treating infectious diseases, infection-relating diseases, and adverse reactions of vaccines in an individual by administering to the individual a safer vaccine that induce less adverse reactions, or by administering to the individual a pathogenic antigen that neutralize pathogenic antibodies. Yet further provided are methods for identification of the presence of pathogenic antibodies inducible by a pathogen or the vaccines relating to the pathogen.Type: ApplicationFiled: May 21, 2021Publication date: July 18, 2024Inventor: Huiru Wang
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Patent number: 11919968Abstract: The invention provides antibodies that specifically bind to an epitope containing N-acetylglucosamine and specifically bind to an epitope comprising N-acetyl-galactosamine expressed by a cancer cell or an inflammatory cell. Further provided are methods for treating gastrointestinal diseases characterized by inflammatory cells in the intestines or colon in an individual by administering to the individual an antibody that specifically binds to an epitope containing N-acetylglucosamine and specifically binds to an epitope comprising N-acetyl-galactosamine.Type: GrantFiled: July 13, 2022Date of Patent: March 5, 2024Assignee: B & H Biotechnologies, LLCInventor: Huiru Wang
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Patent number: 11903956Abstract: Composition and methods for treating infectious and inflammatory diseases using saccharide based products and therapies. Products can be implemented as a nutritional supplement, a food, a feed, a food additive, a feed additive, a therapeutic product, a rehydration salt, or a rehydration solution. The present disclosure relates generally to the fields of compositions and products containing the compositions, and the use of the compositions or the products for preventing and/or treating infectious or inflammatory diseases or conditions in particular gastrointestinal and respiratory diseases (diarrhea and influenza infections) or inflammatory.Type: GrantFiled: January 10, 2022Date of Patent: February 20, 2024Assignee: B&H BIOTECHNOLOGIES, LLCInventor: Huiru Wang
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Publication number: 20240043509Abstract: The present invention discloses products and the methods of uses of the products for preventing and treating infectious diseases and the disorders or conditions inducible by harmful antibodies. The harmful antibodies are induced during infection, or vaccination, or use of therapeutic antibodies. The products of the present disclosure comprise immunoglobulin products, scrum or plasma, specific antibodies to viral pathogens.Type: ApplicationFiled: August 10, 2023Publication date: February 8, 2024Inventor: Huiru WANG
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Patent number: 11767357Abstract: The present invention discloses products and the methods of uses of the products for preventing and treating infectious diseases and the disorders or conditions inducible by harmful antibodies. The harmful antibodies are induced during infection, or vaccination, or use of therapeutic antibodies. The products of the present disclosure comprise immunoglobulin products, serum or plasma, specific antibodies to viral pathogens.Type: GrantFiled: January 7, 2019Date of Patent: September 26, 2023Assignee: B & H Biotechnologies, LLCInventor: Huiru Wang
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Publication number: 20230138529Abstract: The invention provides antibodies that specifically bind to an epitope containing N-acetylglucosamine or N-acetyl-galactosamine expressed by a cancer cell or an inflammatory cell. Also provided are compositions including these antibodies, as well as polynucleotides, vectors, host cells, and methods useful for production thereof. Further provided are methods and kits for treating or preventing cancer in an individual by administering to the individual an antibody that specifically binds to an epitope containing N-acetylglucosamine or N-acetyl-galactosamine, optionally in combination with another anti-cancer agent. Still further provided are methods and kits for treating or preventing gastrointestinal disease in an individual by administering to the individual an antibody that specifically binds to an epitope containing N-acetylglucosamine or N-acetyl-galactosamine.Type: ApplicationFiled: July 13, 2022Publication date: May 4, 2023Inventor: Huiru WANG
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Publication number: 20230065536Abstract: It provides antibodies and chimeric antigen receptors (CARs) that specifically bind to an epitope containing N-acetyl-glucosamine and/or N-acetyl-galactosamine, e.g., expressed by a cancer cell or an inflammatory cell. Also provided are compositions including these antibodies and/or CARs, as well as polynucleotides, vectors, host cells, methods, and kits related thereto. Further provided are methods and kits for treating or preventing cancer in an individual by administering to the individual an antibody that specifically binds to an epitope containing N-acetylglucosamine or N-acetyl-galactosamine, or a T cell comprising a CAR that specifically binds to an epitope containing N-acetylglucosamine or N-acetyl-galactosamine, optionally in combination with another anticancer agent.Type: ApplicationFiled: August 12, 2022Publication date: March 2, 2023Inventor: Huiru WANG
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Patent number: 11446328Abstract: It provides antibodies and chimeric antigen receptors (CARs) that specifically bind to an epitope containing N-acetyl-glucosamine and/or N-acetyl-galactosamine, e.g., expressed by a cancer cell or an inflammatory cell. Also provided are compositions including these antibodies and/or CARs, as well as polynucleotides, vectors, host cells, methods, and kits related thereto. Further provided are methods and kits for treating or preventing cancer in an individual by administering to the individual an antibody that specifically binds to an epitope containing N-acetylglucosamine or N-acetyl-galactosamine, or a T cell comprising a CAR that specifically binds to an epitope containing N-acetylglucosamine or N-acetyl-galactosamine, optionally in combination with another anti-cancer agent.Type: GrantFiled: February 17, 2017Date of Patent: September 20, 2022Assignee: B & H BIOTECHNOLOGIES, LLCInventor: Huiru Wang
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Patent number: 11421039Abstract: The invention provides antibodies that specifically bind to an epitope containing N-acetylglucosamine or N-acetyl-galactosamine expressed by a cancer cell or an inflammatory cell. Also provided are compositions including these antibodies, as well as polynucleotides, vectors, host cells, and methods useful for production thereof. Further provided are methods and kits for treating or preventing cancer in an individual by administering to the individual an antibody that specifically binds to an epitope containing N-acetylglucosamine or N-acetyl-galactosamine, optionally in combination with another anti-cancer agent. Still further provided are methods and kits for treating or preventing gastrointestinal disease in an individual by administering to the individual an antibody that specifically binds to an epitope containing N-acetylglucosamine or N-acetyl-galactosamine.Type: GrantFiled: February 7, 2020Date of Patent: August 23, 2022Assignee: B & H Biotechnologies, LLCInventor: Huiru Wang
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Publication number: 20220211733Abstract: Composition and methods for treating infectious and inflammatory diseases using saccharide based products and therapies. Products can be implemented as a nutritional supplement, a food, a feed, a food additive, a feed additive, a therapeutic product, a rehydration salt, or a rehydration solution. The present disclosure relates generally to the fields of compositions and products containing the compositions, and the use of the compositions or the products for preventing and/or treating infectious or inflammatory diseases or conditions in particular gastrointestinal and respiratory diseases (diarrhea and influenza infections) or inflammatory.Type: ApplicationFiled: January 10, 2022Publication date: July 7, 2022Inventor: Huiru Wang
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Patent number: 11285166Abstract: The present disclosure discloses simple and efficient glycan- or carbohydrate-based processes or methods for the rapid identification of biological markers and therapeutic targets especially glycan-related targets of infectious diseases, cancers, autoimmune diseases, allergies, inflammation, toxicity, obesity and/or other disorders of humans, animals, plants and other organisms. Therefore, novel methods and products for the diagnosis, prevention, and treatment of such diseases obtainable based on these therapeutic targets can be developed.Type: GrantFiled: June 7, 2019Date of Patent: March 29, 2022Assignee: B&H BIOTECHNOLOGIES, LLCInventor: Huiru Wang
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Patent number: 11246878Abstract: Composition and methods for treating infectious and inflammatory diseases using saccharide based products and therapies. Products can be implemented as a nutritional supplement, a food, a feed, a food additive, a feed additive, a therapeutic product, a rehydration salt, or a rehydration solution. The present disclosure relates generally to the fields of compositions and products containing the compositions, and the use of the compositions or the products for preventing and/or treating infectious or inflammatory diseases or conditions in particular gastrointestinal and respiratory diseases (diarrhea and influenza infections) or inflammatory.Type: GrantFiled: March 13, 2014Date of Patent: February 15, 2022Assignee: B&H BIOTECHNOLOGIES, LLCInventor: Huiru Wang
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Publication number: 20200239591Abstract: The invention provides antibodies that specifically bind to an epitope containing N-acetylglucosamine or N-acetyl-galactosamine expressed by a cancer cell or an inflammatory cell. Also provided are compositions including these antibodies, as well as polynucleotides, vectors, host cells, and methods useful for production thereof. Further provided are methods and kits for treating or preventing cancer in an individual by administering to the individual an antibody that specifically binds to an epitope containing N-acetylglucosamine or N-acetyl-galactosamine, optionally in combination with another anti-cancer agent. Still further provided are methods and kits for treating or preventing gastrointestinal disease in an individual by administering to the individual an antibody that specifically binds to an epitope containing N-acetylglucosamine or N-acetyl-galactosamine.Type: ApplicationFiled: February 7, 2020Publication date: July 30, 2020Applicant: B & H Biotechnologies, LLCInventor: Huiru WANG
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Patent number: 10597461Abstract: Provided are antibodies that specifically bind to an epitope containing N-acetylglucosamine or N-acetyl-galactosamine expressed by a cancer cell or an inflammatory cell. Also provided are compositions including these antibodies, as well as polynucleotides, vectors, host cells, and methods useful for production thereof. Further provided are methods and kits for treating or preventing cancer in an individual by administering to the individual an antibody that specifically binds to an epitope containing N-acetylglucosamine or N-acetyl-galactosamine, optionally in combination with another anti-cancer agent. Still further provided are methods and kits for treating or preventing gastrointestinal disease in an individual by administering to the individual an antibody that specifically binds to an epitope containing N-acetylglucosamine or N-acetyl-galactosamine.Type: GrantFiled: August 21, 2015Date of Patent: March 24, 2020Assignee: B & H Biotechnologies, LLCInventor: Huiru Wang
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Publication number: 20190388447Abstract: The present disclosure discloses simple and efficient glycan- or carbohydrate-based processes or methods for the rapid identification of biological markers and therapeutic targets especially glycan-related targets of infectious diseases, cancers, autoimmune diseases, allergies, inflammation, toxicity, obesity and/or other disorders of humans, animals, plants and other organisms. Therefore, novel methods and products for the diagnosis, prevention, and treatment of such diseases obtainable based on these therapeutic targets can be developed.Type: ApplicationFiled: June 7, 2019Publication date: December 26, 2019Inventor: Huiru WANG
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Publication number: 20190270792Abstract: The present invention discloses products and the methods of uses of the products for preventing and treating infectious diseases and the disorders or conditions inducible by harmful antibodies. The harmful antibodies are induced during infection, or vaccination, or use of therapeutic antibodies. The products of the present disclosure comprise immunoglobulin products, serum or plasma, specific antibodies to viral pathogens.Type: ApplicationFiled: January 7, 2019Publication date: September 5, 2019Inventor: Huiru WANG
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Patent number: 10342812Abstract: The present disclosure discloses simple and efficient glycan- or carbohydrate-based processes or methods for the rapid identification of biological markers and therapeutic targets especially glycan-related targets of infectious diseases, cancers, autoimmune diseases, allergies, inflammation, toxicity, obesity and/or other disorders of humans, animals, plants and other organisms. Therefore, novel methods and products for the diagnosis, prevention, and treatment of such diseases obtainable based on these therapeutic targets can be developed.Type: GrantFiled: July 20, 2015Date of Patent: July 9, 2019Assignee: B&H BIOTECHNOLOGIES, LLCInventor: Huiru Wang
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Patent number: 10202439Abstract: The present invention discloses products and the methods of uses of the products for preventing and treating infectious diseases and the disorders or conditions inducible by harmful antibodies. The harmful antibodies are induced during infection, or vaccination, or use of therapeutic antibodies. The products of the present disclosure comprise immunoglobulin products, serum or plasma, specific antibodies to viral pathogens.Type: GrantFiled: March 13, 2014Date of Patent: February 12, 2019Assignee: B&H BIOTECHNOLOGIES, LLCInventor: Huiru Wang
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Patent number: D1027304Type: GrantFiled: June 3, 2022Date of Patent: May 14, 2024Inventor: Huiru Wang