Patents by Inventor Huiwen ZHENG

Huiwen ZHENG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12215358
    Abstract: Provided is a Coxsackievirus A6 (CVA6) strain CVA6-KM-J33 and use thereof, and belongs to the technical field of biomedicine. The present invention provides a CVA6 strain CVA6-KM-J33, which belongs to a CVA6 virus. In the present invention, the strain CVA6-KM-J33 is susceptible to KMB17 cells and can achieve a relatively high titer. The strain has strong virulence, high pathogenicity and lethality to suckling mice, and desirable immunogenicity, and is a highly effective virus strain for CVA6 vaccine development. This strain can be used for immunogenicity evaluation or protective evaluation of CVA6 vaccine to improve the accuracy and reproducibility of vaccine immunogenicity evaluation. This strain can also be used to prepare animal models of Coxsackievirus (CV) infection, and exhibits desirable application prospects.
    Type: Grant
    Filed: May 3, 2024
    Date of Patent: February 4, 2025
    Assignee: INSTITUTE OF MEDICAL BIOLOGY, CAMS
    Inventors: Longding Liu, Li Yu, Guorun Jiang, Dandan Li, Heng Zhao, Huiwen Zheng, Ying Zhang, Yun Liao, Haijing Shi, Xin Zhao, Heng Li
  • Patent number: 12060389
    Abstract: An enterovirus multi-antigen epitope fusion protein, a gene, a vaccine and a preparation method thereof are provided, relating to the field of vaccine preparation technologies. The amino acid sequence of the enterovirus multi-antigen epitope fusion protein is shown in SEQ ID NO: 4. The vaccine is prepared by adopting the preparation method of a genetically engineered protein vaccine, and the prepared vaccine has stronger specificity. After protein purification, there are fewer impure proteins and more specific antigen proteins, thus improving the effectiveness and safety of the combined vaccine.
    Type: Grant
    Filed: January 13, 2024
    Date of Patent: August 13, 2024
    Assignee: INSTITUTE OF MEDICAL BIOLOGY, CHINESE ACADEMY OF MEDICAL SCIENCES
    Inventors: Longding Liu, Huiwen Zheng, Heng Li, Xin Zhao, Li Yu, Guorun Jiang, Dandan Li, Heng Zhao, Ying Zhang, Yun Liao, Haijing Shi
  • Patent number: 11988270
    Abstract: The disclosure relates to the technical field of electric drive assemblies, and in particular provides an electric drive assembly for an electric vehicle, and an electric vehicle. The disclosure provides an electric drive assembly composed of an input shaft integrated with an electric motor rotor and a gearbox first-stage driving gear, three intermediate shafts each integrated with a gearbox first-stage driven gear and a second-stage driving gear, and a differential integrated with a second-stage driven gear. The three intermediate shafts are evenly disposed around the input shaft. The power of the electric motor is transmitted from the first-stage driving gear to the second-stage driven gear on the differential evenly through the three intermediate shafts.
    Type: Grant
    Filed: December 1, 2022
    Date of Patent: May 21, 2024
    Assignee: NIO TECHNOLOGY (ANHUI) CO., LTD
    Inventors: Xin Fan, Chuanwei Ren, Zhengcheng Huang, Xiaochao Chu, Yangpeng Shi, Huiwen Zheng
  • Publication number: 20230175579
    Abstract: The disclosure relates to the technical field of electric drive assemblies, and in particular provides an electric drive assembly for an electric vehicle, and an electric vehicle. The disclosure provides an electric drive assembly composed of an input shaft integrated with an electric motor rotor and a gearbox first-stage driving gear, three intermediate shafts each integrated with a gearbox first-stage driven gear and a second-stage driving gear, and a differential integrated with a second-stage driven gear. The three intermediate shafts are evenly disposed around the input shaft. The power of the electric motor is transmitted from the first-stage driving gear to the second-stage driven gear on the differential evenly through the three intermediate shafts.
    Type: Application
    Filed: December 1, 2022
    Publication date: June 8, 2023
    Inventors: Xin FAN, Chuanwei REN, Zhengcheng HUANG, Xiaochao CHU, Yangpeng SHI, Huiwen ZHENG