Abstract: Provided are transaminase mutants and uses thereof. The transaminase mutant is obtained by one or more amino acid mutations occurring in SEQ ID NO: 2 or is a mutant with a conserved amino acid mutation obtained by taking the sequence SEQ ID NO: 1 of a wild-type CvTA transaminase as a reference. Compared with wild-type transaminases, the catalytic activity of the mutant is improved to different degrees, so that the production efficiency of chiral amine compound synthesis may be improved.

Abstract: The present application describes compartmentalized arrays of printed linker molecules with physical barriers on the surface, the physical barriers forming one or more compartments surrounding and separating at least a portion of the plurality of distinct regions. The present application also describes a method of fabrication and uses of the compartmentalized arrays.

Abstract: A polarizing device and a method for manufacturing the polarizing device, a display panel and a display device are provided. The polarizing device comprises a first polarizing layer and at least two second polarizing layers, wherein each of two sides of the first polarizing layer is provided with respective at least one of the second polarizing layers; a light transmission axis of the first polarizing layer is parallel to the first polarizing layer, a phase delay axis of the second polarizing layer is parallel to the second polarizing layer, an orthographic projection of the light transmission axis onto the first polarizing layer intersects with an orthographic projection of the phase delay axis onto the first polarizing layer to form an included angle, the included angle is configured to convert linear polarized light incident on the polarization assembly into polarized light emitted from the polarization assembly.

Abstract: A curved display module and a display device, where the curved display module includes a back plate, a display panel and a display panel circuit board. The back plate includes a bottom plate and a side plate, where the side plate is at an outer periphery of the bottom plate, the bottom plate and the side plate together define an accommodating space to accommodate a backlight assembly, the display panel is on a side of the backlight assembly away from the bottom plate, the display panel circuit board is electrically connected to the display parcel through a flexible circuit board, and the display panel circuit board is at an outer side of the side plate.

Abstract: Disclosed are a curved backlight module and a display device. The curved backlight module includes: an optical film and a lamp board which are oppositely provided, the distance between the optical film and the lamp board being referred to as an optical cavity height; the lamp board is provided with a plurality of lamp bars which extend in a first direction and are arranged in a second direction, a plurality of lamp beads distributed in an array are provided on each of the lamp bars, and the distribution parameters of the lamp beads on each of the lamp bars are the same; and on each of the lamp bars, there is a first distance between two adjacent lamp beads in the first direction, and there is a second distance between two adjacent lamp beads in the second direction.

Abstract: A curved display module and a curved display device. The curved display module can be bent along a long-side direction, and comprises a display panel (1), a backlight module (2), a front frame (3), a back plate (4), an XPCB (6), and an FPC (5); the FPC (5) is provided at a first long-side edge of the display panel (1) and is configured to connect the binding region of the first long-side edge of the display panel (1) to the XPCB (6); the first long-side edge of the back plate (4) is in the shape of staircase, and comprises a back surface (41), a slope surface (42), and a step surface (43) that are sequentially connected from the direction distant from the first long-side edge to the direction close to the first long-side edge.

Abstract: A backlight unit includes: a back plate including a bottom wall and a side wall around a periphery of the bottom wall; a lamp strip including a substrate and lamp beads on the substrate; a light guide plate on a side of the bottom wall provided with the side wall, the lamp strip being on a first side wall of the side wall, and light emitting surfaces of the lamp beads being opposite to a side surface of the light guide plate; and a position limiting and fixing structure between the light guide plate and each of the back plate and the lamp strip, for limiting and fixing a position of the lamp strip relative to the light guide plate to keep a gap between the light emitting surfaces of the lamp beads and a light incident surface of the light guide plate unchanged during turn-over of the backlight unit.

Abstract: A backlight assembly includes a first sub-optical film with first edge portions, and a supporting frame including a first supporting portion which includes rims. At least one rim includes a first positioning groove and second positioning grooves, the first edge portion includes a first positioning portion in the first positioning groove and second positioning portions in the second positioning grooves; a difference between sizes of the first positioning groove and the first positioning portion is a first space, a difference between a size of each second positioning groove and that of the second positioning portion is a second space greater than the first space; the first edge portions include a first sub-edge portion, the first positioning portion is located at a midpoint of the first sub-edge portion, and the second positioning portions are distributed on both sides of the first positioning portion.

Abstract: Disclosed are a curved backlight module and a display device. The curved backlight module includes: an optical film and a lamp board which are oppositely provided, the distance between the optical film and the lamp board being referred to as an optical cavity height; the lamp board is provided with a plurality of lamp bars which extend in a first direction and are arranged in a second direction, a plurality of lamp beads distributed in an array are provided on each of the lamp bars, and the distribution parameters of the lamp beads on each of the lamp bars are the same; and on each of the lamp bars, there is a first distance between two adjacent lamp beads in the first direction, and there is a second distance between two adjacent lamp beads in the second direction.

Abstract: An obtaining method for image coordinates of a position invisible to a camera, a calibration method and a system are disclosed. A first color image and corresponding depth image of a position to be measured invisible to a main camera are obtained from a depth camera. The depth camera is positioned so that the position to be measured is within a field of view of the depth camera. Three-dimensional coordinates of the position to be measured are extracted from the first color image and corresponding depth image. And the three-dimensional coordinates of the position to be measured are converted into the required image coordinates of the position to be measured by a translation matrix and a rotation matrix for converting a depth camera coordinate system into a main camera coordinate system. The translation matrix and the rotation matrix are determined by calibration between the main camera and the depth camera.

Abstract: A backlight unit includes: a back plate including a bottom wall and a side wall around a periphery of the bottom wall; a lamp strip including a substrate and lamp beads on the substrate; a light guide plate on a side of the bottom wall provided with the side wall, the lamp strip being on a first side wall of the side wall, and light emitting surfaces of the lamp beads being opposite to a side surface of the light guide plate; and a position limiting and fixing structure between the light guide plate and each of the back plate and the lamp strip, for limiting and fixing a position of the lamp strip relative to the light guide plate to keep a gap between the light emitting surfaces of the lamp beads and a light incident surface of the light guide plate unchanged during turn-over of the backlight unit.

Abstract: A polarizing device and a method for manufacturing the polarizing device, a display panel and a display device are provided. The polarizing device comprises a first polarizing layer and at least two second polarizing layers, wherein each of two sides of the first polarizing layer is provided with respective at least one of the second polarizing layers; a light transmission axis of the first polarizing layer is parallel to the first polarizing layer, a phase delay axis of the second polarizing layer is parallel to the second polarizing layer, an orthographic projection of the light transmission axis onto the first polarizing layer intersects with an orthographic projection of the phase delay axis onto the first polarizing layer to form an included angle, the included angle is configured to convert linear polarized light incident on the polarization assembly into polarized light emitted from the polarization assembly.

Abstract: A backlight driving board includes a main circuit board, and a photosensitive device, a backlight controller and a first port that are disposed on the main circuit board. The photosensitive device is configured to sense brightness and color temperature of a light source, and output brightness data and color temperature data. The backlight controller is coupled to the photosensitive device, and configured to receive the brightness data and adjust light-emitting brightness of the light source according to the brightness data. The first port is coupled to the photosensitive device, and configured to be coupled to a system board, receive the color temperature data, and transmit the color temperature data to the system board, such that the system board adjusts color temperature of a picture displayed by a display panel according to the color temperature data.

Abstract: A backlight assembly and a display device are provided. The backlight assembly includes a first sub-optical film including first edge portions and a supporting frame including a first supporting portion which includes rims. The rim includes a first positioning groove and second positioning grooves, the first edge portion includes a first positioning portion in the first positioning groove and second positioning portions in the second positioning grooves; a difference between sizes of the first positioning groove and the first positioning portion is a first space, a difference between a size of each second positioning groove and that of the second positioning portion is a second space greater than the first space; the first edge portions include a first sub-edge portion, the first positioning portion is located at a midpoint of the first sub-edge portion, and the second positioning portions are distributed on both sides of the first positioning portion.

Abstract: A curved surface display device includes a display panel, a first middle frame located on a side of the display panel and configured to support the display panel, a backlight assembly located at a side of the first middle frame away from the display panel and having an optical film and a second middle frame, and a back plate located at a side of the backlight assembly away from the display panel. The back plate includes a bottom plate and a side plate disposed on an edge of the bottom plate; the second middle frame is located at a side of the optical film away from the display panel, and is connected to the bottom plate.

Abstract: A curved surface display device, a vehicle and a backlight assembly are provided. The curved surface display device includes a display panel, a first middle frame, a backlight assembly and a back plate. The first middle frame is located on a non-display side of the display panel and configured to support the display panel; the backlight assembly is located at a side of the first middle frame away from the display panel and includes an optical film and a second middle frame, the second middle frame is located at a side of the optical film away from the display panel; the back plate is located at a side of the backlight assembly away from the display panel. The back plate includes a bottom plate and a side plate disposed on an edge of the bottom plate, and the second middle frame is connected to the bottom plate.

Abstract: Rapid and specific detection of biological cells and biomolecules is important to biological assays across diverse fields including genomics, proteomics, diagnoses, and pathological studies. Microarrays and microfluidics increasingly dominate such detection techniques due to the ability to perform significant numbers of tests with limited sample volumes. A snap chip assembly is provided for the transfer of a microarray of reagents within semi-spherical liquid droplets on a transfer chip to a target assay microarray on an assay chip following assembly of the two chips and physical contact of the droplets with the target array. Reagents in nanoliter quantities are spotted on both chips and selectively transferred as liquid droplets between transfer chip and assay chip within the contact areas. Using the snap chip structure the inventors performed immunoassays with colocalization of capture and detection antibodies with 10 targets and bead-in-gel droplet microarrays with 9 targets in the low pg/ml regime.

Abstract: Disclosed is a use of the CUEDC2 protein in the preparation of diagnostic agents for prognostic determination of the endocrinology therapy for the breast cancer patients and for the diagnosis of tumor such as breast cancer and ovarian cancer. The diagnostic agent comprises an antibody against the CUEDC2 protein, wherein the antibody is a monoclonal or polyclonal antibody against the CUEDC2 protein. Provided is a kit or a composition for prognostic determination of endocrinology therapy for the breast cancer patients and for the diagnosis of tumors such as breast cancer and ovarian cancer. The kit or composition comprises an antibody against the CUEDC2 protein. Further disclosed is a use of the CUEDC2 gene or protein in preparation of drugs for treating tumors, that is, small molecular substances and specific antibodies that specifically inhibit the expression or activity of the CUEDC2 gene\protein are used as a therapeutic agent to restore the sensitivity of drug-resistant tumors to drug treatment.

Abstract: Disclosed is a use of the CUEDC2 protein in the preparation of diagnostic agents for prognostic determination of the endocrinology therapy for the breast cancer patients and for the diagnosis of tumor such as breast cancer and ovarian cancer. The diagnostic agent comprises an antibody against the CUEDC2 protein, wherein the antibody is a monoclonal or polyclonal antibody against the CUEDC2 protein. Provided is a kit or a composition for prognostic determination of endocrinology therapy for the breast cancer patients and for the diagnosis of tumors such as breast cancer and ovarian cancer. The kit or composition comprises an antibody against the CUEDC2 protein. Further disclosed is a use of the CUEDC2 gene or protein in preparation of drugs for treating tumors, that is, small molecular substances and specific antibodies that specifically inhibit the expression or activity of the CUEDC2 gene\protein are used as a therapeutic agent to restore the sensitivity of drug-resistant tumors to drug treatment.

Abstract: Rapid and specific detection of biological cells and biomolecules is important to biological assays across diverse fields including genomics, proteomics, diagnoses, and pathological studies. Microarrays and microfluidics increasingly dominate such detection techniques due to the ability to perform significant numbers of tests with limited sample volumes. A snap chip assembly is provided for the transfer of a microarray of reagents within semi-spherical liquid droplets on a transfer chip to a target assay microarray on an assay chip following assembly of the two chips and physical contact of the droplets with the target array. Reagents in nanolitre quantities are spotted on both chips and selectively transferred as liquid droplets between transfer chip and assay chip within the contact areas. Using the snap chip structure the inventors performed immunoassays with colocalization of capture and detection antibodies with 10 targets and bead-in-gel droplet microarrays with 9 targets in the low pg/ml regime.