Patents by Inventor Huiyong MA

Huiyong MA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DNA-ENCODED COMPOUND LIBRARY AND SCREENING METHOD THEREOF
    Publication number: 20230295610
    Abstract: A synthesis and screening method of a DNA-encoded compound library. The DNA-encoded compound library consists of a DNA-encoded compound of formula (I). The screening method includes: incubating the DNA-encoded compound library with a protein target, followed by covalent cross-linking to obtain a covalently cross-linked complex; separating the covalently cross-linked complex from members in the library that do not bind to the protein target; and subjecting the covalently cross-linked complex to polymerase chain reaction (PCR) amplification and DNA sequencing.
    Type: Application
    Filed: May 26, 2023
    Publication date: September 21, 2023
    Inventors: Jin LI, Guansai LIU, Huadong LUO, Liu CHEN, Junyang ZHU, Huiyong MA, Chao SONG, Jinqiao WAN