Patents by Inventor Huizhen ZHAO

Huizhen ZHAO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Genetically modified non-human animals with humanized immunoglobulin locus
    Patent number: 11730151
    Abstract: The present disclosure relates to genetically modified animals and cells with humanized heavy chain immunoglobulin locus and/or humanized light chain immunoglobulin locus.
    Type: Grant
    Filed: October 12, 2022
    Date of Patent: August 22, 2023
    Assignee: Biocytogen Pharmaceuticals (Beijing) Co., Ltd.
    Inventors: Yuelei Shen, Jiawei Yao, Huizhen Zhao, Yabo Zhang, Lili Liu, Hui Lu, Shuwen Huang
  • GENETICALLY MODIFIED NON-HUMAN ANIMALS WITH COMMON LIGHT CHAIN IMMUNOGLOBULIN LOCUS
    Publication number: 20230128645
    Abstract: This disclosure relates to genetically modified animals and cells with humanized light chain immunoglobulin locus and/or humanized heavy chain immunoglobulin locus. In one aspect, the endogenous light chain immunoglobulin locus comprises a limit number of human IGKV genes and human IGKJ genes.
    Type: Application
    Filed: October 19, 2022
    Publication date: April 27, 2023
    Inventors: Yabo Zhang, Hui LU, Huizhen ZHAO, Jiawei Yao, Yi Yang, Yuelei Shen
  • GENETICALLY MODIFIED NON-HUMAN ANIMALS WITH HUMANIZED IMMUNOGLOBULIN LOCUS
    Publication number: 20230064196
    Abstract: The present disclosure relates to genetically modified animals and cells with humanized heavy chain immunoglobulin locus and/or humanized light chain immunoglobulin locus.
    Type: Application
    Filed: October 12, 2022
    Publication date: March 2, 2023
    Inventors: Yuelei Shen, Jiawei Yao, Huizhen ZHAO, Yabo ZHANG, Lili Liu, Hui LU, Shuwen HUANG
  • GENETICALLY MODIFIED NON-HUMAN ANIMALS WITH HUMANIZED IMMUNOGLOBULIN LOCUS
    Publication number: 20200390073
    Abstract: The present disclosure relates to genetically modified animals and cells with humanized heavy chain immunoglobulin locus and/or humanized light chain immunoglobulin locus.
    Type: Application
    Filed: September 2, 2020
    Publication date: December 17, 2020
    Inventors: Yuelei Shen, Jiawei Yao, Huizhen ZHAO, Yabo ZHANG, Lili Liu, Hui LU, Shuwen HUANG