Patents by Inventor Humera Jahan

Humera Jahan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Role of novel carbazole linked 1, 2, 3- triazole analogs in alleviating methylglyoxal-mediated late diabetic vascular complications
    Patent number: 11925622
    Abstract: The present intervention identifies the antiglycating inhibitors from a series of carbazole-linked 1,2,3 triazole derivatives through in vitro MGO-mediated glycating BSA model. Derivatives 12, and 13 established a remarkable antiglycation activity at the receptor level in human monocytes. These compounds were found non-toxic, and possess the potential to halt AGE-RAGE/ROS-mediated NF-kB-dependent COX-2, and its proinflammatory product, PGE2, production in monocytes. Hence, carbazole-linked 1,2,3 triazole derivatives provide treatment modalities to delay or prevent the onset of late diabetic micro- and macro-vascular complications in diabetic patients.
    Type: Grant
    Filed: August 20, 2021
    Date of Patent: March 12, 2024
    Inventors: Humera Jahan, Mohammad Iqbal Choudhary, Nimra Naz Siddiqui, Fatima Z. Basha, Shazia Iqbal
  • Role Of Novel Carbazole Linked 1, 2, 3- Triazole Analogs in Alleviating Methylglyoxal-Mediated Late Diabetic Vascular Complications
    Publication number: 20230054099
    Abstract: The present intervention identifies the antiglycating inhibitors from a series of carbazole-linked 1,2,3 triazole derivatives through in vitro MGO-mediated glycating BSA model. Derivatives 12, and 13 established a remarkable antiglycation activity at the receptor level in human monocytes. These compounds were found non-toxic, and possess the potential to halt AGE-RAGE/ROS- mediated NF- kB-dependent COX-2, and its proinflammatory product, PGE2, production in monocytes. Hence, carbazole-linked 1,2,3 triazole derivatives provide treatment modalities to delay or prevent the onset of late diabetic micro- and macro-vascular complications in diabetic patients.
    Type: Application
    Filed: August 20, 2021
    Publication date: February 23, 2023
    Inventors: Humera Jahan, Mohammad Iqbal Choudhary, Nimra Naz Siddiqui, Fatima Z. Basha, Shazia Iqbal
  • 2, 4-dinitroanilino-benzoic acid: novel insulinotropic agent for the treatment of diabetes
    Patent number: 10183000
    Abstract: The current study established that treatment of diabetes using compound 1(2,4-dinitroanilino-benzoic acid), an anthranilic acid derivative, by restoring the functional activities of the pancreas via its insulinotropic action.
    Type: Grant
    Filed: August 22, 2017
    Date of Patent: January 22, 2019
    Inventors: Humera Jahan, Muhammad Iqbal Choudhary, Mehwish Manzoor, Khalid M. Khan, Atta-ur Rahman
  • Inhibitors of advanced glycation end-products (ages)formation
    Patent number: 9387198
    Abstract: The invention relates to methods of inhibiting the protein glycation process and the associated formation of Advanced Glycation End products (AGEs) in hyperglycemia by administering 6-Nitrobenzimidazole derivatives. These derivatives were found to be effective not merely against the formation of AGE, but they can inhibit the action of AGEs at post-receptor levels.
    Type: Grant
    Filed: February 27, 2015
    Date of Patent: July 12, 2016
    Inventors: Humera Jahan, Muhammad Iqbal Choudhary, Zarbad Shah, Khalid M. Khan, Atta-ur Rahman
  • Anthranilic acid derivatives: novel inhibitors of advanced glycation end-products (AGEs) formation
    Patent number: 9381182
    Abstract: Anthranilic acid derivatives are used to inhibit the formation of advanced glycation end products to reduce complications in diabetes.
    Type: Grant
    Filed: August 15, 2013
    Date of Patent: July 5, 2016
    Inventors: Muhammad Iqbal Choudhary, Humera Jahan, Kahlid Mohammed Khan, Amber Atta, Atta-ur- Rahman
  • ANTHRANILIC ACID DERIVATIVES: NOVEL INHIBITORS OF ADVANCED GLYCATION END-PRODUCTS (AGES) FORMATION
    Publication number: 20150051286
    Abstract: Anthranilic acid derivatives are used to inhibit the formation of advanced glycation end products to reduce complications in diabetes.
    Type: Application
    Filed: August 15, 2013
    Publication date: February 19, 2015
    Inventors: Muhammad Iqbal Choudhary, Humera Jahan, Kahlid Mohammed Khan, Amber Atta, Atta-ur- Rahman