Patents by Inventor Humio Tamura

Humio Tamura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4938897
    Abstract: Disclosed herein are (1) a fluorescent substance represented by the formula (I), (2) a process for producing the fluorescent substance, and (3) a cell-discriminating agent containing the fluorescent substance as an active ingredient. ##STR1## (wherein n is an integer of 0, 1, 2 or 3 and R represents a residual radical of a fluorescent material.
    Type: Grant
    Filed: June 13, 1986
    Date of Patent: July 3, 1990
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Kiro Asano, Humio Tamura, Tsuyoshi Saito, Hisayuki Wada, Yoichi Suzuki
  • Patent number: 4921849
    Abstract: Disclosed herein is an injection containing 3-benzoyloxy-1,3,5(10)-estratriene-17-[4-{p-bis(2-chloroethyl)amino)phenyl }butanoyloxy]acetate, which has been known as an orally administrable anti-tumor substance, as an active ingredient and an ester of iodinated poppy oil fatty acid as a solvent.
    Type: Grant
    Filed: July 18, 1988
    Date of Patent: May 1, 1990
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Kiro Asano, Satoshi Mitsuhashi, Kenji Bannai, Hisayuki Wada, Humio Tamura
  • Patent number: 4885290
    Abstract: Disclosed herein is an immunoregulator comprising a derivative of estradiol represented by the formula (I), which immunoregulator has a small influence to the non-specific immunoreactions in general and gives a specific influence to the immunoreactions against an isoantibody.
    Type: Grant
    Filed: October 29, 1987
    Date of Patent: December 5, 1989
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Kiro Asano, Tadahiro Matsudaira, Humio Tamura, Toichi Suzuki, Hisayuki Wada
  • Patent number: 4360663
    Abstract: A process for producing a steroid hormone-antitumor derivative which selectively affects to tumor or cancer cells comprises reacting X group of a steroid hormone derivative having the formula ##STR1## wherein ST represents a steroid moiety having a cyclophenanthrene hydrocarbon skeleton of gonane, estrane or androstane which is bound to carboxyl group by esterifying OH group on D ring with carboxyl group; and R' represents a C.sub.1 -C.sub.
    Type: Grant
    Filed: December 2, 1980
    Date of Patent: November 23, 1982
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Kiro Asano, Humio Tamura, Hiromitsu Tanaka, Satoru Enomoto
  • Patent number: 4332797
    Abstract: The Chlorambucil derivatives are novel compounds having the formula (I). ##STR1## wherein R represents a hydrogen atom or an acyl group such as ##STR2## and n is 1 or 2. The Chlorambucil derivatives can be produced by binding Chlorambucil to hydroxyl group at 17-position of estradiol or its derivative in the presence of a binding agent selected from the group consisting of compounds having the formulaX(CH.sub.2).sub.n COOHX(CH.sub.2).sub.n COXHOOC(CH.sub.2).sub.n COOH andXOC(CH.sub.2).sub.n COXwherein n is 1 or 2 and X represents a halogen atom.
    Type: Grant
    Filed: September 12, 1980
    Date of Patent: June 1, 1982
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Kiro Asano, Humio Tamura, Hiromitsu Tanaka, Satoru Enomoto
  • Patent number: 4318908
    Abstract: Methylated prostaglandine derivatives are steroids derivatives having at 17 position, methylated prostaglandine group such as(Me).sub.2 --PGE.sub.2 --E(Me).sub.2 --PGE.sub.2 --E--2AC(Me).sub.2 --PGE.sub.2 --E--BA(Me).sub.2 --PGE.sub.2 --E--2AC--BA(Me)--PGF.sub.2 .alpha.--E(Me)--PGF.sub.2 .alpha.--E--3AC(Me)--PGF.sub.2 .alpha.--E--BA or(Me)--PGF.sub.2 .alpha.--E--3AC--BAor 600 mg/kg of the following active ingredient:(Me).sub.2 --PGE.sub.2 '--E(Me).sub.2 --PGE.sub.2 '--E--2AC(Me).sub.2 --PGE.sub.2 '--E--BA(Me).sub.2 --PGE.sub.2 '--E--2AC--BA(Me)--PGE.sub.2 --E(Me)--PGE.sub.2 --E--2AC(Me)--PGE.sub.2 --E--BA or(Me)--PGE.sub.2 --E--2AC--BA.
    Type: Grant
    Filed: May 27, 1980
    Date of Patent: March 9, 1982
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Satoru Enomoto, Kiro Asano, Humio Tamura, Hiromitsu Tanaka
  • Patent number: 4293533
    Abstract: Solid carbon material having extremely high flexural strength can be produced by introducing a sufficient amount of functional group to satisfy the undernoted general equation into a pitch having a H/C atomic ratio of 0.8 at most, thereby obtaining precursory carbon material; shaping said precursory carbon material into a desired article without using any binding material; and carbonizing or further graphitizing said article; wherein the general equation is ##EQU1## where, H/C is the hydrogen-to-carbon atomic ratio of the pitch, R is a numeral ranging from 0.2 to 0.3, and f is the percent by weight of at least one of oxygen, sulfur and halogen contained in the total functional groups introduced into the precursory carbon material on the basis of the weight thereof.
    Type: Grant
    Filed: January 12, 1977
    Date of Patent: October 6, 1981
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Kiro Asano, Humio Tamura, Yushi Nezu, Tsuyoshi Saito, Yoshio Kawai
  • Patent number: 4261910
    Abstract: The Chlorambucil derivatives are novel compounds having the formula (I). ##STR1## wherein R represents a hydrogen atom or an acyl group such as ##STR2## and n is 1 or 2. The Chlorambucil derivatives can be produced by binding Chlorambucil to hydroxyl group at 17-position of estradiol or its derivative in the presence of a binding agent selected from the group consisting of compounds having the formulaX(CH.sub.2).sub.n COOHX(CH.sub.2).sub.n COXHOOC(CH.sub.2).sub.n COOH andXOC(CH.sub.2).sub.n COXwherein n is 1 or 2 and X represents a halogen atom.
    Type: Grant
    Filed: August 1, 1979
    Date of Patent: April 14, 1981
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Kiro Asano, Humio Tamura, Hiromitsu Tanaka, Satoru Enomoto
  • Patent number: 4260736
    Abstract: A process for producing a steroid hormone-antitumor derivative which selectively affects to tumor or cancer cells comprises reacting X group of a steroid hormone derivative having the formula ##STR1## wherein ST represents a steroid moiety having a cyclophenanthrene hydrocarbon skeleton of gonane, estrane or androstane which is bound to carboxyl group by esterifying OH group on D ring with carboxyl group; and R' represents a C.sub.1 -C.sub.
    Type: Grant
    Filed: August 1, 1979
    Date of Patent: April 7, 1981
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Kiro Asano, Humio Tamura, Hiromitsu Tanaka, Satoru Enomotol
  • Patent number: 4198405
    Abstract: Prostaglandine derivatives are composed of a prostaglandine and a steriod hormone with or without a binding group.The prostaglandine derivatives have extraordinarily reduced side-effect and superior physiological activity, particularly effect of abortion in comparison with those of prostaglandines.
    Type: Grant
    Filed: January 5, 1979
    Date of Patent: April 15, 1980
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Satoru Enomoto, Kiro Asano, Humio Tamura, Hiromitsu Tanaka
  • Patent number: 4042486
    Abstract: Crystalloidal pitch is obtained by subjecting solid pitch particles measuring not more than 5 mm in cross-sectional equivalent diameter to a treatment to prevent cohesion and subsequently bringing the cohesion-proof solid pitch particles into contact with a non-oxidative gas at temperatures of from 350.degree. C to 550.degree. C while maintaining a gas flow rate sufficient to provide a suspension wherein the gas constitutes at least 30% by volume. The crystalloid pitch is useful as a precursor for various carbon products.
    Type: Grant
    Filed: March 10, 1976
    Date of Patent: August 16, 1977
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Kiro Asano, Humio Tamura, Tsuyoshi Saito, Yoshio Kawai