Patents by Inventor Hunho Jo

Hunho Jo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ASSAY METHOD FOR POINT OF CARE QUANTIFICATION OF AN IMMUNOPHILIN-BINDING IMMUNOSUPPRESSANT DRUG
    Publication number: 20230333128
    Abstract: Methods and apparatuses, including assays, for detection and/or quantification of tacrolimus that utilize nucleic acid-based nanostructures linked to tacrolimus. In particular, described herein are biosensors having a sensing mechanism configured to react to a tacrolimus-specific binding agent, such as an aptamer or antibody that binds tacrolimus. In some variations, these methods and apparatuses may be configured to provide an electrochemical read-out in which the nucleic acid-based nanostructure is operated in conjunction with a tacrolimus-specific binding agent for sample quantification. A biosensor or a set of biosensors as described herein can be used as a standalone measurement system for tacrolimus and/or as part of a multiplexed cartridge for multiple analytes.
    Type: Application
    Filed: June 26, 2020
    Publication date: October 19, 2023
    Inventors: Subramaniam SOMASUNDARAM, Anup SINGH, Eshwar INAPURI, Christopher J. EASLEY, Hunho JO
  • DNA aptamer specifically binding to EN2 (engrailed-2) and use thereof
    Patent number: 9429575
    Abstract: The present invention relates to a DNA aptamer specifically binding to EN2 (Engrailed-2), a biosensor for diagnosing prostate cancer having the same, and a method of diagnosing prostate cancer. A strong binding force and excellent specificity of the DNA aptamer of the present invention and the biosensor using the same with respect to EN2 proteins were identified. A detection specificity problem of a prostate-specific antigen (PSA) test used for prostate cancer diagnosis of the related art was addressed. Therefore, the present invention is expected to be beneficially used for early diagnosis of prostate cancer more effectively and increase diagnostic accuracy.
    Type: Grant
    Filed: November 5, 2015
    Date of Patent: August 30, 2016
    Assignee: Postech Academy-Industry Foundation
    Inventors: Changill Ban, Yoon-Keun Kim, Hunho Jo, Seonghwan Lee, Hyung Jun Youn
  • DNA Aptamer Specifically Binding to EN2 (Engrailed-2) and Use Thereof
    Publication number: 20160187342
    Abstract: The present invention relates to a DNA aptamer specifically binding to EN2 (Engrailed-2), a biosensor for diagnosing prostate cancer having the same, and a method of diagnosing prostate cancer. A strong binding force and excellent specificity of the DNA aptamer of the present invention and the biosensor using the same with respect to EN2 proteins were identified. A detection specificity problem of a prostate-specific antigen (PSA) test used for prostate cancer diagnosis of the related art was addressed. Therefore, the present invention is expected to be beneficially used for early diagnosis of prostate cancer more effectively and increase diagnostic accuracy.
    Type: Application
    Filed: November 5, 2015
    Publication date: June 30, 2016
    Inventors: Changill Ban, Yoon-Keun Kim, Hunho Jo, Seonghwan Lee, Hyung Jun Youn