Patents by Inventor Hunter Champion

Hunter Champion has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PDE5 inhibitor compositions and methods for treating cardiac indications
    Patent number: 8299083
    Abstract: The invention features methods and compositions featuring a PDE5 inhibitor for treating or preventing a cardiac indication in a subject.
    Type: Grant
    Filed: August 17, 2005
    Date of Patent: October 30, 2012
    Assignee: The Johns Hopkins University
    Inventors: David Kass, Eiki Takimoto, Hunter Champion
  • COMPOSITIONS AND METHODS OF TREATING ENDOTHELIAL DISORDERS
    Publication number: 20120065165
    Abstract: Compositions and methods of treating endothelial disorders, including: asthma, erectile dysfunction, pulmonary hypertension, cardiovascular disorders, and other disorders, using a synergistic combination of at least one arginase inhibitor and at least one phosphodiesterase (PDE1), (PDE2) and/or (PDE5) inhibitor are described.
    Type: Application
    Filed: November 2, 2009
    Publication date: March 15, 2012
    Applicant: ARGINETIX, INC
    Inventors: Simon E. Aspland, Dan E. Berkowitz, Trinity Bivalacqua, Hunter Champion
  • Use of a Nitric Oxide Synthase Modulator for the Treatment of Cardiac Indications
    Publication number: 20100004248
    Abstract: The invention features compositions and methods for modulating NOS that are useful for the prevention and treatment of cardiac diseases and disorders, including cardiac hypertrophy and cardiac dilation. In particular, the invention provides compositions comprising tetrahydrobiopterin (BH4), alone or in combination with one or more additional compounds.
    Type: Application
    Filed: October 23, 2006
    Publication date: January 7, 2010
    Inventors: David Kass, Eiki Takimoto, Hunter Champion, Moens An
  • Arginase II: A Target treatment of aging heart and heart failure
    Publication number: 20090298912
    Abstract: The instant invention provides methods and compositions for the treatment of cardiac dysfunction. Specifically, the invention provides methods and compositions for modulating Arginase II for the treatment of cardiac dysfunction.
    Type: Application
    Filed: June 29, 2006
    Publication date: December 3, 2009
    Applicant: The Johns Hopkins University
    Inventors: Dan E. Berkowitz, Joshua M. Hare, Artin A. Shoukas, Hunter Champion, Jochen Steppan
  • Pde5 inhibitor compositions and methods for treating cardiac indications
    Publication number: 20090062313
    Abstract: The invention features methods and compositions featuring a PDE5 inhibitor for treating or preventing a cardiac indication in a subject.
    Type: Application
    Filed: August 17, 2005
    Publication date: March 5, 2009
    Applicant: THE JOHNS HOPKINS UNIVERSITY
    Inventors: David Kass, Eiki Takimoto, Hunter Champion
  • Methods to improve creatine kinase metabolism and contractile function in cardiac muscle for the treatment of heart failure
    Publication number: 20070265221
    Abstract: The present invention relates to novel treatments of mammalian and human heart failure directed at improving cardiac creatine kinase metabolism, the prime energy reserve of cardiac muscle. The invention also relates to novel treatments using gene transfer vectors to increase myocardial creatine kinase protein expression and/or creatine kinase activity, as well as flux through the creatine kinase reaction and to thereby improve cardiac contractile function and ameliorate remodeling in heart failure. The invention further relates to methods for screening and identifying compounds that increase creatine kinase expression and/or creatine kinase activity as potential pharmaceutical compositions for heart failure therapy.
    Type: Application
    Filed: May 8, 2007
    Publication date: November 15, 2007
    Inventors: Robert Weiss, Hunter Champion