Abstract: Systems and methods of the present disclosure are configured to determine relevance associated with one or more diseases, conditions and treatments. Based on condition-related criteria and condition-related criteria logic rules derived therefrom, each cardiac patient may be assessed for the relevance of cardiac treatments based on each cardiac patient's EHR data. As such, the condition-related criteria logic rules encode criteria for the applicability of each cardiac treatment based on patient health data, tests, metrics or other factors or any combination thereof. One or more parsers are configured according to the condition-related criteria logic rules to determine a relevance indicator of each cardiac treatment to each cardiac patient. Based on the relevance indicators, a patient list for each cardiac treatment may be updated with the cardiac patients for which the cardiac treatment is relevant.