Patents by Inventor Huong Dang
Huong Dang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9204882Abstract: A vasoocclusive coil is reinforced with a stretch resistant member to improve safety during retraction of the coil. The stretch resistant member is fixedly attached at one end to the vasoocclusive coil, and the other end of the stretch resistant member is detachably mounted to an elongated pusher member to allow for placement and release of the vasoocclusive coil within the patient's vasculature. The stretch resistant member may be formed from a therapeutic and/or bioactive non-metallic material to enhance the therapeutic properties of the vasoocclusive coil.Type: GrantFiled: August 21, 2013Date of Patent: December 8, 2015Assignee: DEPUY SYNTHES PRODUCTS, INC.Inventors: Peter Wilson, Eric W. Leopold, Rupesh K. Desai, Diane Mai-Huong Dang
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Patent number: 8673336Abstract: An implantable drug delivery device loaded with a beneficial agent is provided, wherein the beneficial agent is in two different forms, a first form having a higher solubility and a second form having a lower solubility, and wherein the two different forms are present in a proportion which is selected to achieve a desired release rate.Type: GrantFiled: December 17, 2010Date of Patent: March 18, 2014Assignee: Innovational Holdings LLCInventors: Theodore L. Parker, Stephen Hunter Diaz, John F. Shanley, Diane Mai Huong Dang, Thai Minh Nguyen
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Publication number: 20130338701Abstract: A vasoocclusive coil is reinforced with a stretch resistant member to improve safety during retraction of the coil. The stretch resistant member is fixedly attached at one end to the vasoocclusive coil, and the other end of the stretch resistant member is detachably mounted to an elongated pusher member to allow for placement and release of the vasoocclusive coil within the patient's vasculature. The stretch resistant member may be formed from a therapeutic and/or bioactive non-metallic material to enhance the therapeutic properties of the vasoocclusive coil.Type: ApplicationFiled: August 21, 2013Publication date: December 19, 2013Applicant: Micrus CorporationInventors: Peter Wilson, Eric W. Leopold, Rupesh K. Desai, Diane Mai-Huong Dang
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Patent number: 8540671Abstract: A vasoocclusive coil is reinforced with a stretch resistant member to improve safety during retraction of the coil. The stretch resistant member is fixedly attached at one end to the vasoocclusive coil, and the other end of the stretch resistant member is detachably mounted to an elongated pusher member to allow for placement and release of the vasoocclusive coil within the patient's vasculature. The stretch resistant member may be formed from a therapeutic and/or bioactive non-metallic material to enhance the therapeutic properties of the vasoocclusive coil.Type: GrantFiled: October 3, 2011Date of Patent: September 24, 2013Assignee: Micrus CorporationInventors: Peter Wilson, Eric W. Leopold, Rupesh K. Desai, Diane Mai-Huong Dang
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Publication number: 20120179194Abstract: A vasoocclusive coil is reinforced with a stretch resistant member to improve safety during retraction of the coil. The stretch resistant member is fixedly attached at one end to the vasoocclusive coil, and the other end of the stretch resistant member is detachably mounted to an elongated pusher member to allow for placement and release of the vasoocclusive coil within the patient's vasculature. The stretch resistant member may be formed from a therapeutic and/or bioactive non-metallic material to enhance the therapeutic properties of the vasoocclusive coil.Type: ApplicationFiled: October 3, 2011Publication date: July 12, 2012Applicant: MICRUS CORPORATIONInventors: Peter WILSON, Eric W. LEOPOLD, Rupesh K. DESAI, Diane Mai-Huong DANG
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Patent number: 8029464Abstract: A vasoocclusive coil is reinforced with a stretch resistant member to improve safety during retraction of the coil. The stretch resistant member is fixedly attached at one end to the vasoocclusive coil, and the other end of the stretch resistant member is detachably mounted to an elongated pusher member to allow for placement and release of the vasoocclusive coil within the patient's vasculature. The stretch resistant member may be formed from a therapeutic and/or bioactive non-metallic material to enhance the therapeutic properties of the vasoocclusive coil.Type: GrantFiled: May 16, 2006Date of Patent: October 4, 2011Assignee: Micrus CorporationInventors: Peter Wilson, Eric W. Leopold, Rupesh K. Desai, Diane Mai-Huong Dang
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Publication number: 20110086082Abstract: An implantable drug delivery device loaded with a beneficial agent is provided, wherein the beneficial agent is in two different forms, a first form having a higher solubility and a second form having a lower solubility, and wherein the two different forms are present in a proportion which is selected to achieve a desired release rate.Type: ApplicationFiled: December 17, 2010Publication date: April 14, 2011Applicant: Innovational Holdings, LLCInventors: Theodore L. PARKER, Stephen Hunter Diaz, John F. Shanley, Diane Mai Huong Dang, Thai Minh Nguyen
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Publication number: 20090287166Abstract: A system and method in accordance with the present invention provides a infusion catheter that is flexible, has such a smooth traction and a low profile to minimize break up of the obstruction when crossing it, can access distal vasculature quickly, is easy to use and readily to be implemented in the conventional PCI. Another object is to provide a method that can be performed within a short period of time and employs the catheter described herein to infuse a therapeutic agent distally to the obstruction before it is removed as a means of reducing reperfusion injury, protecting distal vasculature and microcirculation, preserving myocytes, reducing infarct size and ischemic damages in the heart, brain, lung, liver, kidney and limb. Another object is to provide complementary feature options to the infusion catheter and the aspiration catheter to improve the speed and quality of the vessel clearance.Type: ApplicationFiled: May 19, 2008Publication date: November 19, 2009Applicant: CNA Tek Inc.Inventor: Diane Mai Huong Dang
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Publication number: 20090226600Abstract: A multi-step method of forming a coating on a substrate, such as a stent or graft, is disclosed. The steps of the method include treating the surface with a plasma formed at or near atmospheric pressure to form one or more active species on the surface until a desired surface density of the active species is formed, and exposing the treated surface to a selected gas or liquid under conditions effective to convert the active species to a stable functional group. The exposed surface may be contacted with a surface-modifying group under conditions effective to covalently attach the surface-modifying group to the functional group. Also disclosed is a substrate having a bioactive/biocompatible coating and/or a drug-releasable coating prepared by the method.Type: ApplicationFiled: May 15, 2009Publication date: September 10, 2009Inventors: Mai Huong Dang, Phillip Chiu
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Publication number: 20090062899Abstract: A composite expandable stent for delivery into a vessel carrying blood comprising an expandable support frame having first and second end portions. A porous imprevious polymer sleeve having inner and outer surfaces extending over the support frame. A coating is disposed on at least one of the inner and outer surfaces of the polymer sleeve for enhancing endothelial cell growth on the device and polymer sleeve. The stent can be cylindrical or tapered.Type: ApplicationFiled: April 25, 2008Publication date: March 5, 2009Applicant: NFOCUS NEUROMEDICAL, INC.Inventors: Mai Huong DANG, Phillip CHIU, Leon V. RUDAKOV, Kevin T. LARKIN, Mir A. IMRAN
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Publication number: 20090043375Abstract: A composite expandable device for delivery into a vessel carrying blood comprising an expandable support frame having first and second end portions. An impervious polymer sleeve having inner and outer surfaces extending over the support frame. A coating is disposed on at least one of the inner and outer surfaces of the polymer sleeve for enhancing endothelial cell growth on the device and polymer sleeve.Type: ApplicationFiled: April 18, 2008Publication date: February 12, 2009Applicant: NFOCUS NEUROMEDICAL, INC.Inventors: Leon V. RUDAKOV, Mir A. IMRAN, Ara DAVIDIAN, Kevin T. LARKIN, Mai Huong DANG, Phillip CHIU
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Patent number: 7422569Abstract: A vasoocclusive coil is reinforced with a stretch resistant member to improve safety during retraction of the coil. The stretch resistant member is fixedly attached at one end to the vasoocclusive coil, and the other end of the stretch resistant member is detachably mounted to an elongated pusher member to allow for placement and release of the vasoocclusive coil within the patient's vasculature. The stretch resistant member may be formed from a therapeutic and/or bioactive non-metallic material to enhance the therapeutic properties of the vasoocclusive coil.Type: GrantFiled: September 30, 2003Date of Patent: September 9, 2008Assignee: Micrus Endovascular CorporationInventors: Peter Wilson, Eric W. Leopold, Rupesh K. Desai, Diane Mai-Huong Dang
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Publication number: 20070134764Abstract: The invention disclosed in this patent document relates to transmembrane receptors, more particularly to a human G protein-coupled receptor for which the endogenous ligand is unknown, and to mutated (non-endogenous) versions of the human GPCRs for evidence of constitutive activity.Type: ApplicationFiled: November 20, 2006Publication date: June 14, 2007Applicant: Arena Pharmaceuticals, Inc.Inventors: Ruoping Chen, Zhi Chu, Huong Dang, Kevin Lowitz, Cameron Pride
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Publication number: 20070122878Abstract: The invention disclosed in this patent document relates to transmembrane receptors, more particularly to endogenous, human orphan G protein-coupled receptors.Type: ApplicationFiled: May 4, 2006Publication date: May 31, 2007Inventors: Ruoping Chen, Huong Dang, Chen Liaw, I-Lin Lin
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Publication number: 20070079392Abstract: The present invention relates to methods of identifying whether a candidate compound is a modulator of a G protein-coupled receptor (GPCR). In preferred embodiments, the GPCR is human. In other preferred embodiments, the GPCR is coupled to Gi and lowers the level of intracellular cAMP. In other preferred embodiments, the GPCR is expressed endogenously by adipocytes. In further preferred embodiments, the GPCR inhibits intracellular lipolysis. In other further preferred embodiments, the GPCR is a nicotinic acid receptor. The present invention also relates to methods of using a modulator of said GPCR. Preferred modulator is agonist. Agonists of the invention are useful as therapeutic agents for the prevention or treatment of metabolic-related disorders, including dyslipidemia, atherosclerosis, coronary heart disease, stroke, insulin resistance, and type 2 diabetes.Type: ApplicationFiled: November 22, 2006Publication date: April 5, 2007Applicant: Arena Pharmaceuticals, Inc.Inventors: Chen Liaw, Dominic Behan, Derek Chalmers, Michael Lerner, Huong Dang, Bryan Choi, James Leonard, Yaron Hakak, Kevin Lowitz, David Unett, Ruoping Chen, Jeremy Richman, Daniel Connolly
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Publication number: 20070065917Abstract: The invention disclosed in this patent document relates to transmembrane receptors, more particularly to a human G protein-coupled receptor for which the endogenous ligand is unknown (“orphan GPCR receptors”), and most particularly to mutated (non-endogenous) versions of the human GPCRs for evidence of constitutive activity.Type: ApplicationFiled: November 22, 2006Publication date: March 22, 2007Applicant: Arena Pharmaceuticals, Inc.Inventors: Ruoping Chen, Huong Dang, Kevin Lowitz
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Publication number: 20060234350Abstract: The invention disclosed in this patent document relates to transmembrane receptors, more particularly to a human G protein-coupled receptor for which the endogenous ligand is unknown, and to mutated (non-endogenous) versions of the human GPCRs for evidence of constitutive activity.Type: ApplicationFiled: June 22, 2006Publication date: October 19, 2006Applicant: Arena Pharmaceuticals, Inc.Inventors: Ruoping Chen, Zhi Chu, Huong Dang, Kevin Lowitz, Cameron Pride
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Publication number: 20050154029Abstract: The present invention relates to methods of identifying whether a candidate compound is a modulator of a G protein-coupled receptor (GPCR). In preferred embodiments, the GPCR is human. In other preferred embodiments, the GPCR is coupled to Gi and lowers the level of intracellular cAMP. In other preferred embodiments, the GPCR is expressed endogenously by adipocytes. In further preferred embodiments, the GPCR inhibits intracellular lipolysis. In other further preferred embodiments, the GPCR is a nicotinic acid receptor. The present invention also relates to methods of using a modulator of said GPCR. Preferred modulator is agonist. Agonists of the invention are useful as therapeutic agents for the prevention or treatment of metabolic-related disorders, including dyslipidemia, atherosclerosis, coronary heart disease, stroke, insulin resistance, and type 2 diabetes.Type: ApplicationFiled: August 31, 2004Publication date: July 14, 2005Applicant: Arena Pharmaceuticals, Inc.Inventors: David Unett, Ruoping Chen, Jeremy Richman, Daniel Connolly, Huong Dang, Bryan Choi, James Leonard, Yaron Hakak, Chen Liaw, Dominic Behan, Derek Chalmers, Michael Lerner, Kevin Lowitz
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Publication number: 20050004178Abstract: The present invention relates to methods of identifying whether a candidate compound is a modulator of a G protein-coupled receptor (GPCR). In preferred embodiments, the GPCR is human. In other preferred embodiments, the GPCR is coupled to Gi and lowers the level of intracellular cAMP. In other preferred embodiments, the GPCR is expressed endogenously by adipocytes. In further preferred embodiments, the GPCR inhibits intracellular lipolysis. In other further preferred embodiments, the GPCR is a nicotinic acid receptor. The present invention also relates to methods of using a modulator of said GPCR. Preferred modulator is agonist. Agonists of the invention are useful as therapeutic agents for the prevention or treatment of metabolic-related disorders, including dyslipidemia, atherosclerosis, coronary heart disease, stroke, insulin resistance, and type 2 diabetes.Type: ApplicationFiled: July 23, 2004Publication date: January 6, 2005Applicant: Arena Pharmaceuticals, Inc.Inventors: David Unett, Ruoping Chen, Jeremy Richman, Daniel Connolly, Chen Liaw, Dominic Behan, Derek Chalmers, Michael Lerner, Huong Dang, Bryan Choi, James Leonard, Yaron Hakak, Kevin Lowitz
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Publication number: 20030113478Abstract: A multi-step method of forming a coating on a substrate, such as a stent or graft, is disclosed. The steps of the method include treating the surface with a plasma formed at or near atmospheric pressure to form one or more active species on the surface until a desired surface density of the active species is formed, and exposing the treated surface to a selected gas or liquid under conditions effective to convert the active species to a stable functional group. The exposed surface surface may be contacted with a surface-modifying group under conditions effective to covalently attach the surface-modifying group to the functional group. Also disclosed is a substrate having a to bioactive/biocompatible coating and/or a drug-releasable coating prepared by the method.Type: ApplicationFiled: December 12, 2001Publication date: June 19, 2003Inventors: Mai Huong Dang, Phillip Chiu