Patents by Inventor Hussein M. Abou-Issa

Hussein M. Abou-Issa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5010107
    Abstract: The present invention describes a protocol for achieving a very high degree of anticarcinogenic (or chemopreventive or cancer preventative) activity through the combination of a low suboptimal dose of a D-glucarolactone-based dietary anticarcinogen (i.e., calcium glucarate or CGT) with a low suboptimal dose of retinoid-based anticarcinogen (4-hydroxyphenyl retinamide or HPR). Since synergism is obtained by this combination, these two anticarcinogens can be employed at dosages far below toxic levels and at dosages that are practical as a food supplement.
    Type: Grant
    Filed: November 13, 1989
    Date of Patent: April 23, 1991
    Assignee: Ohio State University Research Foundation
    Inventors: John P. Minton, Thomas E. Webb, Hussein M. Abou-Issa
  • Patent number: 5008291
    Abstract: The present invention describes a dietary supplement for achieving a very high degree of chemotherapeutic activity through the synergistic combination of a low suboptimal dose of a D-glucarolactone-based dietary anticarcinogen (calcium glucarate) with a low suboptimal dose of retinoid-based anticarcinogen (4-hydroxyphenyl retinamide).
    Type: Grant
    Filed: November 13, 1989
    Date of Patent: April 16, 1991
    Assignee: Ohio State University Research Foundation
    Inventors: John P. Minton, Thomas E. Webb, Hussein M. Abou-Issa
  • Patent number: 4997852
    Abstract: The present invention describes a protocol for achieving a very high degree of anticarcinogenic (chemopreventive and chemotherapeutic) activity through the combination of low suboptimal doses of a D-glucarolactone-based dietary anticarcinogen with low suboptimal doses of a retinoid-based anticarcinogen. Synergism is obtained by this combination and these two anticarcinogens can be employed at dosages far below toxic levels and at dosages that are practical as a food supplement.
    Type: Grant
    Filed: November 13, 1989
    Date of Patent: March 5, 1991
    Assignee: Ohio State University Research Foundation
    Inventors: John P. Minton, Thomas E. Webb, Hussein M. Abou-Issa