Abstract: A device for the storage, mixing and discharge of liquid and pulverulent materials for medical use has a mixing cylinder (1), a perforated mixing plunger (8), which is axially and rotatably movable in the mixing cylinder (1) by means of an actuation rod (9), an axially displaceable discharge plunger (4), a sealable discharge aperture (3) in the mixing cylinder (1) and means for actuation of the discharge plunger (4). The discharge plunger (4) has in its interior a sealable storage chamber (14) for the accommodation of one of the materials to be mixed, so that pre-packaged amounts of the materials to be mixed can be introduced separately into the device, even without packaging, and stored over an extended period. The discharge plunger (4) engages with the mixing cylinder (1) via an actuation thread, so that rotation of the discharge plunger (4) relative to the mixing cylinder (1) enables discharge of the mixed materials.