Patents by Inventor Huzoor Akbar

Huzoor Akbar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GTPase inhibitors and use thereof for controlling platelet hyperactivity
    Patent number: 7612080
    Abstract: The preferred embodiments generally relate to methods and compositions that affect the GTP-binding activity of members of the Rho family GTPases, preferably Rac (Rac1, Rac2 and/or Rac3), such compositions include compounds that modulate the GTP/GDP exchange activity, along with uses for the compounds including screening for compounds which recognize Rac GTPase, and methods of treating pathological conditions associated or related to a Rho family GTPase, including Rac. The preferred embodiments also relate to methods of using such compounds, or derivatives thereof, e.g., in therapeutics, diagnostics, and as research tools.
    Type: Grant
    Filed: November 18, 2005
    Date of Patent: November 3, 2009
    Assignee: Cincinnati Children's Hospital Medical Center
    Inventors: Yi Zheng, Huzoor Akbar, David A. Williams, Wieslaw Adam Mazur
  • GTPase inhibitors and use thereof for controlling platelet hyperactivity
    Publication number: 20060135542
    Abstract: The preferred embodiments generally relate to methods and compositions that affect the GTP-binding activity of members of the Rho family GTPases, preferably Rac (Rac1, Rac2 and/or Rac3), such compositions include compounds that modulate the GTP/GDP exchange activity, along with uses for the compounds including screening for compounds which recognize Rac GTPase, and methods of treating pathological conditions associated or related to a Rho family GTPase, including Rac. The preferred embodiments also relate to methods of using such compounds, or derivatives thereof, e.g., in therapeutics, diagnostics, and as research tools.
    Type: Application
    Filed: November 18, 2005
    Publication date: June 22, 2006
    Inventors: Yi Zheng, Huzoor Akbar, David Williams, Wieslaw Mazur