Patents by Inventor Hwai-En Ho

Hwai-En Ho has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Systems and methods for obtaining a droplet having a designated concentration of a substance-of-interest
    Patent number: 10450598
    Abstract: Method includes providing a droplet actuator having a droplet-operations gap and a plurality of electrodes positioned along the droplet-operations gap. The method also includes positioning an input droplet in the droplet-operations gap. The input droplet has a starting concentration of a substance-of-interest. The method also includes conducting droplet operations within the droplet-operations gap using the electrodes to generate discrete dilution droplets that are formed from the input droplet. The dilution droplets and a remainder of the input droplet form a droplet set. At least two of the dilution droplets in the droplet set having different concentrations of the substance-of-interest. The method also includes combining a select number of the droplets from the droplet set to form an output droplet having a modified concentration that is substantially equal to a designated target concentration.
    Type: Grant
    Filed: September 8, 2016
    Date of Patent: October 22, 2019
    Assignee: ILLUMINA, INC.
    Inventors: Hwai-En Ho, Gregory F. Smith, Rahul R. Dhopeshwarkar
  • SYSTEMS AND METHODS FOR OBTAINING A DROPLET HAVING A DESIGNATED CONCENTRATION OF A SUBSTANCE-OF-INTEREST
    Publication number: 20170073729
    Abstract: Method includes providing a droplet actuator having a droplet-operations gap and a plurality of electrodes positioned along the droplet-operations gap. The method also includes positioning an input droplet in the droplet-operations gap. The input droplet has a starting concentration of a substance-of-interest. The method also includes conducting droplet operations within the droplet-operations gap using the electrodes to generate discrete dilution droplets that are formed from the input droplet. The dilution droplets and a remainder of the input droplet form a droplet set. At least two of the dilution droplets in the droplet set having different concentrations of the substance-of-interest. The method also includes combining a select number of the droplets from the droplet set to form an output droplet having a modified concentration that is substantially equal to a designated target concentration.
    Type: Application
    Filed: September 8, 2016
    Publication date: March 16, 2017
    Inventors: Hwai-En Ho, Gregory F. Smith, Rahul R. Dhopeshwarkar