Patents by Inventor Hwan Keun Kim

Hwan Keun Kim has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS RELATED TO PROTEIN A (SPA) VARIANTS
    Publication number: 20150056240
    Abstract: The present invention concerns methods and compositions for treating or preventing a bacterial infection, particularly infection by a Staphylococcus bacterium. The invention provides methods and compositions for stimulating an immune response against the bacteria. In certain embodiments, the methods and compositions involve a non-toxigenic Protein A (SpA) variant.
    Type: Application
    Filed: August 22, 2014
    Publication date: February 26, 2015
    Inventors: Olaf SCHNEEWIND, Alice G. Cheng, Dominique M. Missiakas, Hwan Keun Kim
  • Methods and compositions involving protective staphylococcal antigens, such as EBH polypeptides
    Patent number: 8945588
    Abstract: The present invention concerns methods and compositions for treating or preventing a bacterial infection, particularly infection by a Staphylococcus bacterium. The invention provides methods and compositions for stimulating an immune response against the bacteria. In certain embodiments, the methods and compositions involve an Ebh antigen.
    Type: Grant
    Filed: May 7, 2012
    Date of Patent: February 3, 2015
    Assignee: The University of Chicago
    Inventors: Olaf Schneewind, Alice G. Cheng, Dominique M. Missiakas, Hwan Keun Kim
  • COMPOSITIONS AND METHODS RELATED TO PROTEIN A (SPA) ANTIBODIES AS AN ENHANCER OF IMMUNE RESPONSE
    Publication number: 20140335095
    Abstract: The present invention concerns methods and compositions for treating or preventing a bacterial infection, particularly infection by a Staphylococcus bacterium. The invention provides methods and compositions for stimulating an immune response against the bacteria. In certain embodiments, the methods and compositions involve a non-toxigenic Protein A (SpA) variant or an antibody directed thereto.
    Type: Application
    Filed: July 18, 2014
    Publication date: November 13, 2014
    Inventors: Olaf Schneewind, Alice Cheng, Dominique M. Missiakas, Hwan Keun Kim
  • METHODS AND COMPOSITIONS FOR INHIBITING STAPHYLOCOCCUS AGGLUTINATION IN BLOOD
    Publication number: 20140271649
    Abstract: Certain embodiments are directed to methods of inhibiting Staphylococcal infection comprising administering effective amounts of a ClfA inhibitor and a thrombin inhibitor to a patient.
    Type: Application
    Filed: July 13, 2012
    Publication date: September 18, 2014
    Applicant: The University of Chicago
    Inventors: Olaf Schneewind, Dominique Missiakas, Molly Mcadow, Hwan Keun Kim
  • Compositions and methods related to protein A (SpA) variants
    Patent number: 8821894
    Abstract: The present invention concerns methods and compositions for treating or preventing a bacterial infection, particularly infection by a Staphylococcus bacterium. The invention provides methods and compositions for stimulating an immune response against the bacteria. In certain embodiments, the methods and compositions involve a non-toxigenic Protein A (SpA) variant.
    Type: Grant
    Filed: July 1, 2011
    Date of Patent: September 2, 2014
    Assignee: The University of Chicago
    Inventors: Olaf Schneewind, Alice G. Cheng, Dominique M. Missiakas, Hwan Keun Kim
  • Compositions and methods related to protein A (SpA) antibodies as an enhancer of immune response
    Patent number: 8808699
    Abstract: The present invention concerns methods and compositions for treating or preventing a bacterial infection, particularly infection by a Staphylococcus bacterium. The invention provides methods and compositions for stimulating an immune response against the bacteria. In certain embodiments, the methods and compositions involve a non-toxigenic Protein A (SpA) variant or an antibody directed thereto.
    Type: Grant
    Filed: April 5, 2011
    Date of Patent: August 19, 2014
    Assignee: The University of Chicago
    Inventors: Olaf Schneewind, Alice Cheng, Dominique M. Missiakas, Hwan Keun Kim
  • COMPOSITIONS AND METHODS RELATED TO ANTIBODIES TO STAPHYLOCOCCAL PROTEIN A
    Publication number: 20140170134
    Abstract: Embodiments concern methods and compositions for treating or preventing a bacterial infection, particularly infection by a Staphylococcus bacterium. Aspects include methods and compositions for providing a passive immune response against the bacteria. In certain embodiments, the methods and compositions involve an antibody that binds Staphylococcal protein A (SpA).
    Type: Application
    Filed: August 15, 2012
    Publication date: June 19, 2014
    Applicant: The University of Chicago
    Inventors: Olaf Schneewind, Dominique M. Missiakas, Hwan Keun Kim, Carta Emolo, Andrea Dedent
  • COMPOSITIONS AND METHODS RELATED TO ANTIBODIES TO STAPHYLOCOCCAL PROTEINS ISDA OR ISDB
    Publication number: 20140037650
    Abstract: The present invention concerns methods and compositions for treating or preventing a bacterial infection, particularly infection by a Staphylococcus bacterium. The invention provides methods and compositions for providing a passive immune response against the bacteria. In certain embodiments, the methods and compositions involve an antibody, such as a recombinant antibody, that binds IsdA and/or IsdB polypeptides.
    Type: Application
    Filed: August 5, 2013
    Publication date: February 6, 2014
    Applicant: University of Chicago
    Inventors: Hwan Keun Kim, Andrea DeDent, Carla Emolo, Dominique M. Missaikas, Olaf Schneewind
  • COMPOSITIONS AND METHODS RELATED TO ATTENUATED STAPHYLOCOCCAL STRAINS
    Publication number: 20130236419
    Abstract: The present invention concerns methods and compositions for treating or preventing a bacterial infection, particularly infection by a Staphylococcus bacterium. The invention provides methods and compositions for stimulating an immune response against the bacteria. In certain embodiments, the methods and compositions involve attenuated S. aureus strains having deletions in their genome, such as in the srtA and saeR regions.
    Type: Application
    Filed: September 9, 2011
    Publication date: September 12, 2013
    Applicant: THE UNIVERSITY OF CHICAGO
    Inventors: Olaf Schneewind, Hye-Young Kim, Dominique M. Missiakas, Hwan Keun Kim
  • METHODS AND COMPOSITIONS INVOLVING PROTECTIVE STAPHYLOCOCCAL ANTIGENS
    Publication number: 20130230550
    Abstract: The present invention concerns methods and compositions for treating or preventing a bacterial infection, particularly infection by a Staphylococcus bacterium. The invention provides methods and compositions for stimulating an immune response against the bacteria. In certain embodiments, the methods and compositions involve a non-toxigenic Protein A (SpA) variant. In some embodiments, the methods and compositions involve SdrD, ClfA, and/or FnbpB polypeptides.
    Type: Application
    Filed: September 9, 2011
    Publication date: September 5, 2013
    Applicant: The University of Chicago
    Inventors: Olaf Schneewind, Alice G. Cheng, Dominique M. Missiakas, Hwan Keun Kim, Hye-Young Kim
  • COMPOSITIONS AND METHODS RELATED TO PROTEIN A (SpA) ANTIBODIES AS AN ENHANCER OF IMMUNE RESPONSE
    Publication number: 20130136746
    Abstract: The present invention concerns methods and compositions for treating or preventing a bacterial infection, particularly infection by a Staphylococcus bacterium. The invention provides methods and compositions for stimulating an immune response against the bacteria. In certain embodiments, the methods and compositions involve a non-toxigenic Protein A (SpA) variant or an antibody directed thereto.
    Type: Application
    Filed: April 5, 2011
    Publication date: May 30, 2013
    Applicant: The University of Chicago
    Inventors: Olaf Schneewind, Alice Cheng, Dominique M. Missiakas, Hwan Keun Kim
  • METHODS AND COMPOSITIONS INVOLVING PROTECTIVE STAPHYLOCOCCAL ANTIGENS, SUCH AS EBH POLYPEPTIDES
    Publication number: 20120282247
    Abstract: The present invention concerns methods and compositions for treating or preventing a bacterial infection, particularly infection by a Staphylococcus bacterium. The invention provides methods and compositions for stimulating an immune response against the bacteria. In certain embodiments, the methods and compositions involve an Ebh antigen.
    Type: Application
    Filed: May 7, 2012
    Publication date: November 8, 2012
    Inventors: Olaf Schneewind, Alice G. Cheng, Dominique M. Missiakas, Hwan Keun Kim
  • COMPOSITIONS AND METHODS RELATED TO PROTEIN A (SPA) VARIANTS
    Publication number: 20120114686
    Abstract: Disclosed are methods and compositions for treating or preventing a Staphylococcus bacterial infection using a non-toxigenic Protein A (SpA) variant.
    Type: Application
    Filed: April 5, 2010
    Publication date: May 10, 2012
    Applicant: UNIVERSITY OF CHICAGO
    Inventors: Olaf Schneewind, Alice Cheng, Dominique M. Missiakas, Hwan Keun Kim