Abstract: The present specification discloses a method capable of automatically recognizing an accurate wound boundary and a method of generating a 3D wound model based on the recognized wound boundary. The method of automatically recognizing a wound boundary according to the present specification is a method of automatically recognizing a wound boundary based on artificial intelligence, and may photograph several frames of the wound to be recognized with an RGB-D camera, separating measurement information in an image, amplifying image data for learning, and passing the amplified image data through an artificial neural network. The method may include generating a three-dimensional (3D) model by performing boundary recognition post-processing on the data passing through the artificial neural network to match a two-dimensional (2D) image with the 3D model.

Abstract: An active noise control system selects one reference sensor providing a reference signal with the largest coherence to a noise signal, among a plurality of available reference sensors, as a first entry of a reference sensor set. After selecting the first entry, the active noise control system repeats a process in which a sensor capable of providing the largest information quantity to a current reference sensor set among remaining sensors is selected as a new entry of a reference sensor set, until a desired number of sensors is reached or a desired control level is reached. When the reference sensor set is determined, the active noise control system utilizes the entries of the reference sensor set to generates a noise control signal suitable for canceling the noise signal.

Abstract: A method of controlling a three-dimensional (3D) bioprinter includes a nozzle end aligning operation (S100) that includes an operation (a) in which a nozzle end alignment sensor is installed at a predetermined position on a bed in a printing chamber and a sensing point of the nozzle end alignment sensor is positioned at an origin position of the bed, an operation (b) in which the bed is moved toward one side in an X-axis direction and the sensing point of the nozzle end alignment sensor is positioned under a nozzle of a first print module, an operation (c) in which the first print module is moved downward and a Z value of a nozzle end of the first print module is measured, an operation (d) in which the first print module is positioned at an original position and the bed is moved toward the other side in the X-axis direction to position the sensing point of the nozzle end alignment sensor under a syringe, which is disposed at a printing position, of a second print module, an operation (e) in which the second p

Abstract: A three-dimensional (3D) bioprinter includes: a case, a printing chamber surrounded by wall surfaces, a moving unit including a horizontal moving unit installed in a space under a bottom surface of the printing chamber and a vertical moving unit installed outside a side surface of the printing chamber, a bed disposed above a bottom surface opening of the bottom surface of the printing chamber, a first bellows which covers a space between the bed and an inner circumferential surface of the bottom surface opening, a first print module provided in the printing chamber and installed to be vertically movable by the vertical moving unit in a Z-axis direction, a second print module provided at one side of the first print module in the printing chamber and installed to be vertically movable by the vertical moving unit in the Z-axis direction, and a controller.

Abstract: A polythiol composition according to exemplary embodiments includes: a polythiol-based compound; and a benzyl halide-based reaction regulator in an amount of 10 ppm to 2,000 ppm based on a weight of the polythiol-based compound. The reaction rate of the polythiol-based compound and an isocyanate-based compound may be controlled through the reaction regulator to inhibit a generation of stria phenomenon.

Abstract: The present disclosure relates to a method for feeding back reliable downlink channel state information from a receiver to a transmitter in a multi-user massive MIMO system based on a reconfigurable intelligent surface, and more particularly, to a method for the receiver to transform acquired downlink channel state information into downlink channel state information in an angle domain and compress the downlink channel state information through a compressed-sensing scheme, and then feed the compressed result back to the transmitter, and for the transmitter to acquire the reliable downlink channel state information through a recovery algorithm. According to the present disclosure, the downlink channel state information is compressed according to a compression and recovery algorithm in an mmWave environment, and only a codeword index suitable for the compressed result is fed back to the transmitter to obtain the effect of reduction in feedback overhead in the entire communication system.

Abstract: The present invention method for manufacturing a tissue regeneration patch includes: A) preparing a micronized adipose tissue extract; B) injecting the micronized adipose tissue extract into a mold of a predetermined shape; C) cooling the mold into which the adipose tissue extract is injected at a temperature between ?25° C. and ?10° C.; and D) removing the mold to obtain a tissue regeneration patch.

Abstract: A polythiol composition according to exemplary embodiments includes a first polythiol compound which provides a maximum peak in a high performance liquid chromatography (HPLC) analysis graph obtained at a wavelength of 230 nm, and a second polythiol compound having a molecular weight greater than that of the first polythiol compound and represented by C9H20S6. A ratio of a peak area of the second polythiol compound to a peak area of the first polythiol compound, which are measured through the HPLC analysis graph at the wavelength of 230 nm, is 0.05 to 5.0%.

Abstract: A xylylene diisocyanate composition according to exemplary embodiments includes xylylene diisocyanate (XDI) and chloromethylbenzyl isocyanate (CBI), and may satisfy a predetermined relationship between an acidity and a content of CBI. Thereby, an optical lens having a high transmittance and improved optical uniformity can be manufactured by controlling a polymerization reaction rate.

Abstract: A polythiol composition according to exemplary embodiments includes a main polythiol compound and a sub-compound having a molecular weight higher than that of the main polythiol compound. A peak area (%) at retention times ranging from 34 to 40 minutes in the high performance liquid chromatography (HPLC) analysis graph obtained at a wavelength of 230 nm, which corresponds to the sub-compound, is 2.5% or less. An optical product having improved transmittance and optical properties may be manufactured through fine adjustment of the sub-compound.

Abstract: The present disclosure relates to a method for feeding back reliable downlink channel state information from a receiver to a transmitter in a multi-user massive MIMO system based on a reconfigurable intelligent surface, and more particularly, to a method for the receiver to transform acquired downlink channel state information into downlink channel state information in an angle domain and compress the downlink channel state information through a compressed-sensing scheme, and then feed the compressed result back to the transmitter, and for the transmitter to acquire the reliable downlink channel state information through a recovery algorithm. According to the present disclosure, the downlink channel state information is compressed according to a compression and recovery algorithm in an mmWave environment, and only a codeword index suitable for the compressed result is fed back to the transmitter to obtain the effect of reduction in feedback overhead in the entire communication system.

Abstract: The present invention relates to a monomeric streptavidin-expressing gene construct and a host cell into which a recombinant vector comprising the gene construct has been introduced. The gene construct according to the present invention, after injected in vivo through a strain, may express streptavidin, thereby making it possible not only to monitor in real time the location of the strain or a cancer tissue pre-targeted by the strain by using a biotinylated diagnostic agent, but also to increase the cancer targeting efficiency of a biotinylated anticancer agent.

Abstract: The present invention relates to host cells expressing monomeric streptavidin. The host cells according to the present invention may express streptavidin in vivo, making it possible to visualize and monitor in real time the biodistribution of cancer tissue, pre-targeted by the host cell, with a biotinylated diagnostic agent, as well as to increase the cancer-targeting efficiency of biotinylated anticancer drugs.

Abstract: An eco-friendly biodegradable polyester resin composition, including: a polyester resin including a diol, an aromatic dicarboxylic acid and an aliphatic dicarboxylic acid, wherein a soft segment ratio of the polyester resin is 0.21 to 0.29, and wherein the soft segment ratio is a ratio of a diol, bonded between the aliphatic dicarboxylic acid and the aliphatic dicarboxylic acid, among the diols.

Abstract: A polythiol composition according to exemplary embodiments includes at least two different polythiol-based compounds, wherein a peak area (%) of the polythiol compound represented by C8H18S6, which is measured through a high performance liquid chromatographic (HPLC) analysis graph obtained at a wavelength of 230 nm, ranges from 0.90% to 1.30%. By controlling the sub-polythiol compound, an optical product having excellent transmittance and optical properties can be manufactured.

Abstract: The present invention relates to a Salmonella strain that selectively acts on cancer for the treatment of cancer, and a composition for preventing or treating cancer containing the same. In particular, the Salmonella strain according to the present invention has a tumor-suppressing effect, but has a significantly low viability in normal organs, and thus may have a significant anticancer effect compared to conventional inventions.

Abstract: The present disclosure relates to a bio printer to which a biomaterial freeze-hardening method is applied and a freeze-hardening method thereof.

Abstract: A polythiol composition according to exemplary examples includes a tetrafunctional polythiol compound, and a sub-polythiol compound including a compound represented by C13H28S9 and a compound represented by C15H32S10. A ratio of the sub-polythiol compound measured through a high performance liquid chromatography (HPLC) analysis graph is 1% to 5%. By adjusting the content of the sub-polythiol compound, it is possible to manufacture an optical product having excellent transmittance and optical properties.

Abstract: The present invention relates to a 3D bioprinter. The 3D bioprinter, according to the present invention, comprises: a case inside of which a work space is provided; a printing plate installed inside of the case so as slide in the forward, backward, left, and right directions; a first nozzle installed inside the case for dispensing a biomaterial in a solid state on the printing plate; a second nozzle installed inside the case for dispensing a biomaterial in a liquid state on the printing plate; and a control unit for controlling the dispensing by the first nozzle and the second nozzle, wherein the first nozzle and the second nozzle are used to print a single structure by stacking the biomaterial in the solid state and the biomaterial in the liquid state.

Abstract: A drug screening platform simulating hyperthermic intraperitoneal chemotherapy including a dielectrophoresis system, a microfluidic chip and a heating system is disclosed. The dielectrophoresis system is used to provide a dielectrophoresis force. The microfluidic chip includes a cell culture array and observation module and a drug mixing module. The cell culture array and observation module are used to arrange the cells into a three-dimensional structure through the dielectrophoresis force to construct a three-dimensional tumor microenvironment. The drug mixing module is coupled to the cell culture array and observation module and used to automatically split and mix the inputted drugs and output the drug combinations into the cell culture array and observation module.