Abstract: The present invention relates to a heteroaryl derivative compound and a use thereof. Since the heteroaryl derivative of the present invention exhibits excellent inhibitory activity against EGFR, the heteroaryl derivative can be usefully used as a therapeutic agent for EGFR-associated diseases.

Abstract: The present disclosure relates to SH3YL1 monoclonal antibodies and compositions comprising the SH3YL1 monoclonal antibodies. The disclosure also relates to isolated nucleic acid molecules encoding the SH3YL1 antibodies, vectors comprising the nucleic acid molecules, and host cells comprising the vectors. Also disclosed are methods of modulating an immune response, methods of treating diabetic nephropathy, and methods of treating non-alcoholic steatosis hepatitis comprising administering the SH3YL1 antibodies. Also disclosed are methods of treating acute kidney injury and methods of treating inflammatory bowel disease comprising administering the SH3YL1 antibodies.

Abstract: Proposed is a three-dimensional chiral metal nanoparticle, comprising a heterometal nanoparticle including: a seed region formed of a first metal; and a heterogeneous region disposed on an external side of the seed region to enclose the seed region and formed of a second metal. The first metal is gold (Au), and the second metal is palladium (Pd). In a rectangular parallelepiped structure, a rectangular band shape rotates in a clockwise direction or a counterclockwise direction on each surface and protrudes towards a center of the surface.

Abstract: A three-dimensional chiral nanostructure according to an embodiment of the present invention comprises: metal nanoparticles having a chiral structure: and a coating layer enclosing the metal nanoparticles. The metal nanoparticle is formed in a polyhedral structure having an R region and an S region in which atoms are arranged clockwise and counterclockwise, respectively, in the order of (111), (100), and (110) crystal faces on the basis of the chiral center, wherein at least a portion of the edges form a curve tilting and extending from the R or S region so that the metal nanoparticle has a chiral structure.

Abstract: The present disclosure relates to SH3YL1 monoclonal antibodies and compositions comprising the SH3YL1 monoclonal antibodies. The disclosure also relates to isolated nucleic acid molecules encoding the SH3YL1 antibodies, vectors comprising the nucleic acid molecules, and host cells comprising the vectors. Also disclosed are methods of modulating an immune response, methods of treating diabetic nephropathy, and methods of treating non-alcoholic steatosis hepatitis comprising administering the SH3YL1 antibodies. Also disclosed are methods of treating acute kidney injury and methods of treating inflammatory bowel disease comprising administering the SH3YL1 antibodies.

Abstract: Disclosed is a method of providing biological data. The method includes the following steps performed by a data processing device: selecting a biological data set from a biological data pool; encrypting biological data included in the biological data set to produce encrypted biological data; transferring the encrypted biological data to a user; receiving a result of analysis on the encrypted biological data from the user; and transferring information on the encrypted biological data included in the result of the analysis to the user. The data processing device encrypts the biological data with a key determined according to a combination of biological data constituting the biological data set.

Abstract: The present disclosure relates to an encoding method and a decoding method using a chiral metal nanostructure. The encoding method according to an aspect of the present disclosure includes preparing a plurality of metal nanostructures having a chiral structure; obtaining the optical data of the plurality of metal nanostructures, and preparing a security medium including the plurality of metal.

Abstract: A three-dimensional chiral nanostructure according to an embodiment of the present invention comprises: metal nanoparticles having a chiral structure: and a coating layer enclosing the metal nanoparticles. The metal nanoparticle is formed in a polyhedral structure having an R region and an S region in which atoms are arranged clockwise and counterclockwise, respectively, in the order of (111), (100), and (110) crystal faces on the basis of the chiral center, wherein at least a portion of the edges form a curve tilting and extending from the R or S region so that the metal nanoparticle has a chiral structure.

Abstract: Disclosed is a method of providing biological data. The method includes the following steps performed by a data processing device: selecting a biological data set from a biological data pool; encrypting biological data included in the biological data set to produce encrypted biological data; transferring the encrypted biological data to a user; receiving a result of analysis on the encrypted biological data from the user; and transferring information on the encrypted biological data included in the result of the analysis to the user. The data processing device encrypts the biological data with a key determined according to a combination of biological data constituting the biological data set.

Abstract: The present disclosure relates to an encoding method and a decoding method using a chiral metal nanostructure. The encoding method according to an aspect of the present disclosure includes preparing a plurality of metal nanostructures having a chiral structure; obtaining the optical data of the plurality of metal nanostructures, and preparing a security medium including the plurality of metal.

Abstract: A method for operating an electronic device is provided, including: obtaining music information associated with music that is being played by the electronic device; and outputting a visual effect through a display of the electronic device based on the music information. According to another aspect of the disclosure, an electronic device is provided including a display and a processor configured to: obtain music information associated with music that is being played by the electronic device; and output a visual effect through the display based on the music information.

Abstract: Provided is a nanoprobe based on a self-replicating biological material. The nanoprobe includes a binding agent existing in a first region of the biological material and capable of binding specifically to a target analyte, and nanoparticles existing in a second region of the biological material and providing an optical detection signal. The use of the nanoprobe enables quantitative analysis and multiplexed analysis of a target. In addition, the nanoprobe is easy to fabricate on a large scale.

Abstract: A method for operating an electronic device is provided, including: obtaining music information associated with music that is being played by the electronic device; and outputting a visual effect through a display of the electronic device based on the music information. According to another aspect of the disclosure, an electronic device is provided including a display and a processor configured to: obtain music information associated with music that is being played by the electronic device; and output a visual effect through the display based on the music information.

Abstract: Provided is a nanoprobe based on a self-replicating biological material. The nanoprobe includes a binding agent existing in a first region of the biological material and capable of binding specifically to a target analyte, and nanoparticles existing in a second region of the biological material and providing an optical detection signal. The use of the nanoprobe enables quantitative analysis and multiplexed analysis of a target. In addition, the nanoprobe is easy to fabricate on a large scale.