Patents by Inventor Hye In YUM

Hye In YUM has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • STERIC EPITOPE OF CEACAM1, AND ANTI-CEACAM1 ANTIBODY, OR FRAGMENT THEREOF, THAT SPECIFICALLY BINDS TO SAME
    Publication number: 20220289819
    Abstract: A steric epitope of CEACAM1 is disclosed. An anti-CEACAM1 antibody or a fragment thereof, which specifically binds to CEACAM1 is disclosed. A steric epitope of CEACAM1 includes all amino acids in critical positions for specific binding to an anti-CEACAM1 antibody and maintains an appropriate three-dimensional structure, and thus can high affinity for an anti-CEACAM1 antibody. In addition, an antibody, or a fragment thereof, that specifically binds to a steric epitope can effectively suppress CEACAM1-CEACAM1 interaction and CEACAM1-CEACAM6 interaction.
    Type: Application
    Filed: November 7, 2019
    Publication date: September 15, 2022
    Applicants: GREEN CROSS CORPORATION, MOGAM INSTITUTE FOR BIOMEDICAL RESEARCH
    Inventors: Mi-Young OH, Jae-Chul LEE, Hye Young PARK, Hye In YUM, Dong-Sik KIM
  • ANTIBODY TO TIGIT AND USE THEREOF
    Publication number: 20220162310
    Abstract: The present invention relates to: an antibody to T cell Immunoreceptor with Ig and Tyrosine-Based Inhibitory Motif Domains (TIGIT), or an antigen-binding fragment thereof; a nucleic acid encoding same; a vector carrying the nucleic acid; a cell transformed with the vector; a method for producing the antibody or the antigen-binding fragment thereof; and a composition and a composition for combined administration, which comprise same and are for preventing or treating cancer.
    Type: Application
    Filed: May 22, 2020
    Publication date: May 26, 2022
    Inventors: Hye-Young PARK, Eun Jung SONG, Eun Hee LEE, Hye In YUM, Hye Mi NAM, Mun Kyung KIM, Jee Won LEE, Joong Hyuk SHEEN, Min Kyu HUR, So Jung LIM, Ok Jae LIM, Yang Mi LIM, Jong Hwa WON
  • Anti-CEACAM1 antibody and use thereof
    Patent number: 11332528
    Abstract: The present invention provides anti-CEACAM1 antibodies with improved binding abilities specific to CEACAM1, and a use thereof. Anti-CEACAM1 antibodies according to the present invention exhibit superior binding abilities specific to CEACAM1, and also activate the anti-cancer immune functions of cytotoxic T cells and natural killer cells, and thus, each one of them can be effectively used as an anti-cancer agent and a composition for treating cancer.
    Type: Grant
    Filed: March 23, 2018
    Date of Patent: May 17, 2022
    Assignees: MOGAM INSTITUTE FOR BIOMEDICAL RESEARCH, GREEN CROSS CORPORATION
    Inventors: So-Young Eun, Miyoung Oh, Hye-Young Park, Mijung Lee, Aerin Yoon, Hye In Yum, Hyemi Nam, Eunhee Lee, Jongwha Won
  • ANTI-CEACAM1 ANTIBODY AND USE THEREOF
    Publication number: 20200109196
    Abstract: The present invention provides anti-CEACAM1 antibodies with improved binding abilities specific to CEACAM1, and a use thereof. Anti-CEACAM1 antibodies according to the present invention exhibit superior binding abilities specific to CEACAM1, and also activate the anti-cancer immune functions of cytotoxic T cells and natural killer cells, and thus, each one of them can be effectively used as an anti-cancer agent and a composition for treating cancer.
    Type: Application
    Filed: March 23, 2018
    Publication date: April 9, 2020
    Applicants: MOGAM INSTITUTE FOR BIOMEDICAL RESEARCH, GREEN CROSS CORPORATION
    Inventors: So-Young EUN, Miyoung OH, Hye-Young PARK, Mijung LEE, Aerin YOON, Hye In YUM, Hyemi NAM, Eunhee LEE, Jongwha WON