Patents by Inventor Hye-Ja Lee

Hye-Ja Lee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200330350
    Abstract: Provided are a novel pseudoceramide compound and uses thereof. The pseudoceramide has antioxidant, anti-inflammatory, skin whitening, and moisturizing effects. In addition, the pseudoceramide can be synthesized in a simple and economically advantageous manner and is free from problems associated with the preparation of cosmetic formulations resulting from low hydrophilicity, thus being suitable for use in cosmetic applications.
    Type: Application
    Filed: November 22, 2017
    Publication date: October 22, 2020
    Inventors: Jin Oh PARK, Ji Won LEE, Seong Hyeon JEON, Jae Young LEE, Hye Ja LEE, Bo Kyung KWON
  • Publication number: 20200237848
    Abstract: The present invention relates to cosmetic and pharmaceutical compositions each containing a composite extract. More specifically, the present invention provides cosmetic and pharmaceutical compositions, each of which contains, as an active ingredient, a composite extract of an aloe extract and an upland rice extract, leading to excellent moisturizing, anti-inflammatory, and atopy alleviating effects, and thus can be favorably used for prevention, alleviation, and treatment of a skin disease.
    Type: Application
    Filed: October 1, 2018
    Publication date: July 30, 2020
    Inventors: Jin-Oh Park, Ji-Won Lee, Hye-Ja Lee, Ji-Hye Kim, Won-Bo Oh
  • Patent number: 10696623
    Abstract: The present invention relates to a novel phenolic acid derivative compound with whitening and antioxidant activities and use thereof. The phenolic acid derivative compound is a compound represented by Formula 1, which is described in the specification, an isomer thereof or a salt thereof. The compound of the present invention has skin whitening activity to inhibit tyrosinase, thus being suitable for use in a pharmaceutical composition or cosmetic product for skin whitening. In addition, the compound of the present invention is suitable for the prevention or treatment of oxidation-derived skin abnormality or disease such as skin aging due to its antioxidant activity.
    Type: Grant
    Filed: December 9, 2016
    Date of Patent: June 30, 2020
    Assignee: DAEBONG LS, LTD
    Inventors: Jin Oh Park, Ji Won Lee, Jae Young Lee, Hye Ja Lee, Bo kyung Kwon
  • Publication number: 20180362448
    Abstract: The present invention relates to a novel phenolic acid derivative compound with whitening and antioxidant activities and use thereof. The phenolic acid derivative compound is a compound represented by Formula 1, which is described in the specification, an isomer thereof or a salt thereof. The compound of the present invention has skin whitening activity to inhibit tyrosinase, thus being suitable for use in a pharmaceutical composition or cosmetic product for skin whitening. In addition, the compound of the present invention is suitable for the prevention or treatment of oxidation-derived skin abnormality or disease such as skin aging due to its antioxidant activity.
    Type: Application
    Filed: December 9, 2016
    Publication date: December 20, 2018
    Inventors: Jin Oh PARK, Ji Won LEE, Jae Young LEE, Hye Ja LEE, Bo kyung KWON
  • Patent number: 8372961
    Abstract: Disclosed are concatameric proteins comprising two soluble domains, in which the C-terminus of a soluble domain of a biologically active protein is linked to the N-terminus of an identical soluble domain or a distinct soluble domain of a biologically active protein. Also, the present invention discloses dimeric proteins formed by formation of intermolecular disulfide bonds at the hinge region of two monomeric proteins formed by linkage of a concatamer of two identical soluble extracellular regions of proteins involving immune response to an Fc fragment of an immunoglobulin molecule, their glycosylated proteins, DNA constructs encoding the monomeric proteins, recombinant expression plasmids containing the DNA construct, host cells transformed or transfected with the recombinant expression plasmids, and a method of preparing the dimeric proteins by culturing the host cells. Further, the present invention discloses pharmaceutical or diagnostic compositions comprising the dimeric protein or its glycosylated form.
    Type: Grant
    Filed: January 22, 2010
    Date of Patent: February 12, 2013
    Assignee: Medexgen Co., Ltd.
    Inventors: Yong-Hoon Chung, Ji-Woong Han, Hye-Ja Lee, Eun-Yong Choi, Jin-Mi Kim
  • Publication number: 20100278827
    Abstract: Disclosed are concatameric proteins comprising two soluble domains, in which the C-terminus of a soluble domain of a biologically active protein is linked to the N-terminus of an identical soluble domain or a distinct soluble domain of a biologically active protein. Also, the present invention discloses dimeric proteins formed by formation of intermolecular disulfide bonds at the hinge region of two monomeric proteins formed by linkage of a concatamer of two identical soluble extracellular regions of proteins involving immune response to an Fc fragment pf an immunoglobulin molecule, their glycosylated proteins, DNA constructs encoding the monomeric proteins, recombinant expression plasmids containing the DNA construct, host cells transformed or transfected with the recombinant expression plasmids, and a method of preparing the dimeric proteins by culturing the host cells. Further, the present invention discloses pharmaceutical or diagnostic compositions comprising the dimeric protein or its glycosylated form.
    Type: Application
    Filed: January 22, 2010
    Publication date: November 4, 2010
    Applicant: Medexgen Co., Ltd.
    Inventors: Yong-Hoon CHUNG, Ji-Woong Han, Hye-Ja Lee, Eun-Yong Choi, Jin-Mi Kim
  • Patent number: 7670602
    Abstract: Disclosed are concatameric proteins comprising two soluble domains, in which the C-terminus of a soluble domain of a biologically active protein is linked to the N-terminus of an identical soluble domain or a distinct soluble domain of a biologically active protein. Also, the present invention discloses dimeric proteins formed by formation of intermolecular disulfide bonds at the hinge region of two monomeric proteins formed by linkage of a concatamer of two identical soluble extracellular regions of proteins involving immune response to an Fc fragment of an immunoglobulin molecule, their glycosylated proteins, DNA constructs encoding the monomeric proteins, recombinant expression plasmids containing the DNA construct, host cells transformed or transfected with the recombinant expression plasmids, and a method of preparing the dimeric proteins by culturing the host cells. Further, the present invention discloses pharmaceutical or diagnostic compositions comprising the dimeric protein or its glycosylated form.
    Type: Grant
    Filed: April 24, 2007
    Date of Patent: March 2, 2010
    Assignee: Medexgen Co., Ltd
    Inventors: Yong-Hoon Chung, Ji-Woong Han, Hye-Ja Lee, Eun-Yong Choi, Jin-Mi Kim
  • Publication number: 20090011466
    Abstract: Disclosed are concatameric proteins comprising two soluble domains, in which the C-terminus of a soluble domain of a biologically active protein is linked to the N-terminus of an identical soluble domain or a distinct soluble domain of a biologically active protein. Also, the present invention discloses dimeric proteins formed by formation of intermolecular disulfide bonds at the hinge region of two monomeric proteins formed by linkage of a concatamer of two identical soluble extracellular regions of proteins involving immune response to an Fc fragment of an immunoglobulin molecule, their glycosylated proteins, DNA constructs encoding the monomeric proteins, recombinant expression plasmids containing the DNA construct, host cells transformed or transfected with the recombinant expression plasmids, and a method of preparing the dimeric proteins by culturing the host cells. Further, the present invention discloses pharmaceutical or diagnostic compositions comprising the dimeric protein or its glycosylated form.
    Type: Application
    Filed: April 24, 2007
    Publication date: January 8, 2009
    Applicant: MEDEXGEN CO., LTD.
    Inventors: Yong-Hoon CHUNG, Ji-Woong HAN, Hye-Ja LEE, Eun-Yong CHOI, Jin-Mi KIM
  • Patent number: 7229962
    Abstract: Disclosed are concatameric proteins comprising two soluble domains, in which the C-terminus of a soluble domain of a biologically active protein is linked to the N-terminus of an identical soluble domain or a distinct soluble domain of a biologically active protein. Also, the present invention discloses dimeric proteins formed by formation of intermolecular disulfide bonds at the hinge region of two monomeric proteins formed by linkage of a concatamer of two identical soluble extracellular regions of proteins involving immune response to an Fc fragment of an immunoglobulin molecule, their glycosylated proteins, DNA constructs encoding the monomeric proteins, recombinant expression plasmids containing the DNA construct, host cells transformed or transfected with the recombinant expression plasmids, and a method of preparing the dimeric proteins by culturing the host cells. Further, the present invention discloses pharmaceutical or diagnostic compositions comprising the dimeric protein or its glycosylated form.
    Type: Grant
    Filed: July 26, 2002
    Date of Patent: June 12, 2007
    Assignee: Medexgen Co., Ltd.
    Inventors: Yong-Hoon Chung, Ji-Woong Han, Hye-Ja Lee, Eun-Yong Choi, Jin-Mi Kim
  • Publication number: 20030195338
    Abstract: Disclosed are concatameric proteins comprising two soluble domains, in which the C-terminus of a soluble domain of a biologically active protein is linked to the N-terminus of an identical soluble domain or a distinct soluble domain of a biologically active protein. Also, the present invention discloses dimeric proteins formed by formation of intermolecular disulfide bonds at the hinge region of two monomeric proteins formed by linkage of a concatamer of two identical soluble extracellular regions of proteins involving immune response to an Fc fragment of an immunoglobulin molecule, their glycosylated proteins, DNA constructs encoding the monomeric proteins, recombinant expression plasmids containing the DNA construct, host cells transformed or transfected with the recombinant expression plasmids, and a method of preparing the dimeric proteins by culturing the host cells. Further, the present invention discloses pharmaceutical or diagnostic compositions comprising the dimeric protein or its glycosylated form.
    Type: Application
    Filed: February 28, 2003
    Publication date: October 16, 2003
    Inventors: Yong-Hoon Chung, Ji-Woong Han, Hye-Ja Lee, Eun-Yong Choi, Jin-Mi Kim