Patents by Inventor Hye-Ja Lee

Hye-Ja Lee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240000699
    Abstract: The present invention relates to a cosmetic composition including a Lycium chinense mill (“Goji berry”) fermented extract and/or green tea fermented extract, and a method for preparing the same. Specifically, there is provided a cosmetic composition with excellent antioxidant, wrinkle improvement and whitening effects, and a method for preparing the same.
    Type: Application
    Filed: July 9, 2021
    Publication date: January 4, 2024
    Inventors: Hye-Ja LEE, Ji Hye KIM, Tae-Heon OH, Yun KIM, Jin Oh PARK
  • Publication number: 20230173008
    Abstract: The present disclosure relates to a composition that is capable of preventing hair loss and promoting hair growth by comprising the extract of the above-ground part of carrots. The composition comprising the extract of the above-ground part of carrots of the present disclosure significantly increases the viability of dermal papilla cells and can inhibit the expression of 5a-reductase, thereby exhibiting excellent effects in preventing hair loss and promoting hair growth.
    Type: Application
    Filed: July 16, 2021
    Publication date: June 8, 2023
    Inventors: Hyun Sook Yeom, Ji Hye Kim, Won Bo Oh, Hye JA Lee, Jin Oh Park, Ji Young Moon, Jeong Mi Kim, Byoung Kwon Park, Ji Won Lee
  • Patent number: 11607437
    Abstract: The present invention relates to cosmetic and pharmaceutical compositions each containing a composite extract. More specifically, the present invention provides cosmetic and pharmaceutical compositions, each of which contains, as an active ingredient, a composite extract of an aloe extract and an upland rice extract, leading to excellent moisturizing, anti-inflammatory, and atopy alleviating effects, and thus can be favorably used for prevention, alleviation, and treatment of a skin disease.
    Type: Grant
    Filed: October 1, 2018
    Date of Patent: March 21, 2023
    Assignee: DAEBONG LS, LTD
    Inventors: Jin-Oh Park, Ji-Won Lee, Hye-Ja Lee, Ji-Hye Kim, Won-Bo Oh
  • Publication number: 20220378691
    Abstract: Provided is a cosmetic composition comprising a fermented product of Nuruk, and particularly, a cosmetic composition that can promote collagen synthesis in skin fibroblasts, have antioxidant effects and moisturizing effects, and prevent aging, comprising a fermented product of Nuruk obtained by fermenting grain with yeast mold (Aspergillus), as an active ingredient.
    Type: Application
    Filed: April 11, 2022
    Publication date: December 1, 2022
    Inventors: Ji Hye Kim, Hyun Sook Yeom, Hye Ja Lee, Kyung Man Hahm, Jin Oh Park, Kyoung Hee Jang, Dae Hyun Shin, Ho An Kim, A Rang Kim, DaAe Park
  • Publication number: 20220378688
    Abstract: The present disclosure relates to a moisturizing or anti-atopic composition, including a fatty acid or a fatty acid derivative. More specifically, the present disclosure relates to a moisturizing or anti-atopic composition including at least one compound selected from the group consisting of ethyl linoleate, ?-linolenic acid, and monolinolein as an active ingredient. The composition for moisturizing or anti-atopic dermatitis, according to the present disclosure, has not only low cytotoxicity but also an anti-inflammatory effect, an increase in the amount of moisturizing factor production, an increase in the amount of skin bather strengthening factor production, and an active effect to inhibit the production of atopic factors, so it can be used in various fields such as beauty for improving skin condition, pharmaceuticals, and food.
    Type: Application
    Filed: November 2, 2020
    Publication date: December 1, 2022
    Inventors: Hyun Sook Yeom, Won Bo Oh, Hye JA Lee, Ji Hye Kim, Jeong Mi Kim, Ji Young Moon, Byoung Kwon Park, Jin Oh Park, Ji Won Lee, Nam Ho Lee, Jung Eun Kim
  • Publication number: 20220370337
    Abstract: The present invention relates to a composition including a Tremella fuciformis culture medium extract. The Tremella fuciformis culture medium extract according to the present invention not only has low cytotoxicity but also has the effects of increasing the production amount of a moisturizing factor and the production amounts of collagen and collagen fibers and inhibiting in vivo active oxygen species, and thus can be utilized as a natural product-derived moisturizing, anti-wrinkle, and anti-oxidant functional material, and can be applied in various ways in the beauty and food fields for skin condition improvement.
    Type: Application
    Filed: September 29, 2020
    Publication date: November 24, 2022
    Inventors: Hyun Sook Yeom, Won Bo Oh, Ji Hye Kim, Hye Ja Lee, Jin Oh Park, Ji Won Lee, Chul Ho Kim, Baek Rock Oh, Min Soo Kim, Sun Yeon Heo, Jeong Woo Seo
  • Patent number: 11471390
    Abstract: Provided are a novel pseudoceramide compound and uses thereof. The pseudoceramide has antioxidant, anti-inflammatory, skin whitening, and moisturizing effects. In addition, the pseudoceramide can be synthesized in a simple and economically advantageous manner and is free from problems associated with the preparation of cosmetic formulations resulting from low hydrophilicity, thus being suitable for use in cosmetic applications.
    Type: Grant
    Filed: November 22, 2017
    Date of Patent: October 18, 2022
    Assignee: DAEBONG LS, LTD
    Inventors: Jin Oh Park, Ji Won Lee, Seong Hyeon Jeon, Jae Young Lee, Hye Ja Lee, Bo Kyung Kwon
  • Publication number: 20220023196
    Abstract: Provided is a cosmetic composition for skin improvement including a green barley extract.
    Type: Application
    Filed: August 8, 2020
    Publication date: January 27, 2022
    Inventors: Kyung Rok LEE, Kyung Min KIM, Su Yeong KIM, Ji Mi KANG, So Young SHIN, Ji Hun PARK, Jin Oh PARK, Ji Won LEE, Hye Ja LEE, Ji Hye KIM, Ho Young KIM
  • Publication number: 20200330350
    Abstract: Provided are a novel pseudoceramide compound and uses thereof. The pseudoceramide has antioxidant, anti-inflammatory, skin whitening, and moisturizing effects. In addition, the pseudoceramide can be synthesized in a simple and economically advantageous manner and is free from problems associated with the preparation of cosmetic formulations resulting from low hydrophilicity, thus being suitable for use in cosmetic applications.
    Type: Application
    Filed: November 22, 2017
    Publication date: October 22, 2020
    Inventors: Jin Oh PARK, Ji Won LEE, Seong Hyeon JEON, Jae Young LEE, Hye Ja LEE, Bo Kyung KWON
  • Publication number: 20200237848
    Abstract: The present invention relates to cosmetic and pharmaceutical compositions each containing a composite extract. More specifically, the present invention provides cosmetic and pharmaceutical compositions, each of which contains, as an active ingredient, a composite extract of an aloe extract and an upland rice extract, leading to excellent moisturizing, anti-inflammatory, and atopy alleviating effects, and thus can be favorably used for prevention, alleviation, and treatment of a skin disease.
    Type: Application
    Filed: October 1, 2018
    Publication date: July 30, 2020
    Inventors: Jin-Oh Park, Ji-Won Lee, Hye-Ja Lee, Ji-Hye Kim, Won-Bo Oh
  • Patent number: 10696623
    Abstract: The present invention relates to a novel phenolic acid derivative compound with whitening and antioxidant activities and use thereof. The phenolic acid derivative compound is a compound represented by Formula 1, which is described in the specification, an isomer thereof or a salt thereof. The compound of the present invention has skin whitening activity to inhibit tyrosinase, thus being suitable for use in a pharmaceutical composition or cosmetic product for skin whitening. In addition, the compound of the present invention is suitable for the prevention or treatment of oxidation-derived skin abnormality or disease such as skin aging due to its antioxidant activity.
    Type: Grant
    Filed: December 9, 2016
    Date of Patent: June 30, 2020
    Assignee: DAEBONG LS, LTD
    Inventors: Jin Oh Park, Ji Won Lee, Jae Young Lee, Hye Ja Lee, Bo kyung Kwon
  • Publication number: 20180362448
    Abstract: The present invention relates to a novel phenolic acid derivative compound with whitening and antioxidant activities and use thereof. The phenolic acid derivative compound is a compound represented by Formula 1, which is described in the specification, an isomer thereof or a salt thereof. The compound of the present invention has skin whitening activity to inhibit tyrosinase, thus being suitable for use in a pharmaceutical composition or cosmetic product for skin whitening. In addition, the compound of the present invention is suitable for the prevention or treatment of oxidation-derived skin abnormality or disease such as skin aging due to its antioxidant activity.
    Type: Application
    Filed: December 9, 2016
    Publication date: December 20, 2018
    Inventors: Jin Oh PARK, Ji Won LEE, Jae Young LEE, Hye Ja LEE, Bo kyung KWON
  • Patent number: 8372961
    Abstract: Disclosed are concatameric proteins comprising two soluble domains, in which the C-terminus of a soluble domain of a biologically active protein is linked to the N-terminus of an identical soluble domain or a distinct soluble domain of a biologically active protein. Also, the present invention discloses dimeric proteins formed by formation of intermolecular disulfide bonds at the hinge region of two monomeric proteins formed by linkage of a concatamer of two identical soluble extracellular regions of proteins involving immune response to an Fc fragment of an immunoglobulin molecule, their glycosylated proteins, DNA constructs encoding the monomeric proteins, recombinant expression plasmids containing the DNA construct, host cells transformed or transfected with the recombinant expression plasmids, and a method of preparing the dimeric proteins by culturing the host cells. Further, the present invention discloses pharmaceutical or diagnostic compositions comprising the dimeric protein or its glycosylated form.
    Type: Grant
    Filed: January 22, 2010
    Date of Patent: February 12, 2013
    Assignee: Medexgen Co., Ltd.
    Inventors: Yong-Hoon Chung, Ji-Woong Han, Hye-Ja Lee, Eun-Yong Choi, Jin-Mi Kim
  • Publication number: 20100278827
    Abstract: Disclosed are concatameric proteins comprising two soluble domains, in which the C-terminus of a soluble domain of a biologically active protein is linked to the N-terminus of an identical soluble domain or a distinct soluble domain of a biologically active protein. Also, the present invention discloses dimeric proteins formed by formation of intermolecular disulfide bonds at the hinge region of two monomeric proteins formed by linkage of a concatamer of two identical soluble extracellular regions of proteins involving immune response to an Fc fragment pf an immunoglobulin molecule, their glycosylated proteins, DNA constructs encoding the monomeric proteins, recombinant expression plasmids containing the DNA construct, host cells transformed or transfected with the recombinant expression plasmids, and a method of preparing the dimeric proteins by culturing the host cells. Further, the present invention discloses pharmaceutical or diagnostic compositions comprising the dimeric protein or its glycosylated form.
    Type: Application
    Filed: January 22, 2010
    Publication date: November 4, 2010
    Applicant: Medexgen Co., Ltd.
    Inventors: Yong-Hoon CHUNG, Ji-Woong Han, Hye-Ja Lee, Eun-Yong Choi, Jin-Mi Kim
  • Patent number: 7670602
    Abstract: Disclosed are concatameric proteins comprising two soluble domains, in which the C-terminus of a soluble domain of a biologically active protein is linked to the N-terminus of an identical soluble domain or a distinct soluble domain of a biologically active protein. Also, the present invention discloses dimeric proteins formed by formation of intermolecular disulfide bonds at the hinge region of two monomeric proteins formed by linkage of a concatamer of two identical soluble extracellular regions of proteins involving immune response to an Fc fragment of an immunoglobulin molecule, their glycosylated proteins, DNA constructs encoding the monomeric proteins, recombinant expression plasmids containing the DNA construct, host cells transformed or transfected with the recombinant expression plasmids, and a method of preparing the dimeric proteins by culturing the host cells. Further, the present invention discloses pharmaceutical or diagnostic compositions comprising the dimeric protein or its glycosylated form.
    Type: Grant
    Filed: April 24, 2007
    Date of Patent: March 2, 2010
    Assignee: Medexgen Co., Ltd
    Inventors: Yong-Hoon Chung, Ji-Woong Han, Hye-Ja Lee, Eun-Yong Choi, Jin-Mi Kim
  • Publication number: 20090011466
    Abstract: Disclosed are concatameric proteins comprising two soluble domains, in which the C-terminus of a soluble domain of a biologically active protein is linked to the N-terminus of an identical soluble domain or a distinct soluble domain of a biologically active protein. Also, the present invention discloses dimeric proteins formed by formation of intermolecular disulfide bonds at the hinge region of two monomeric proteins formed by linkage of a concatamer of two identical soluble extracellular regions of proteins involving immune response to an Fc fragment of an immunoglobulin molecule, their glycosylated proteins, DNA constructs encoding the monomeric proteins, recombinant expression plasmids containing the DNA construct, host cells transformed or transfected with the recombinant expression plasmids, and a method of preparing the dimeric proteins by culturing the host cells. Further, the present invention discloses pharmaceutical or diagnostic compositions comprising the dimeric protein or its glycosylated form.
    Type: Application
    Filed: April 24, 2007
    Publication date: January 8, 2009
    Applicant: MEDEXGEN CO., LTD.
    Inventors: Yong-Hoon CHUNG, Ji-Woong HAN, Hye-Ja LEE, Eun-Yong CHOI, Jin-Mi KIM
  • Patent number: 7229962
    Abstract: Disclosed are concatameric proteins comprising two soluble domains, in which the C-terminus of a soluble domain of a biologically active protein is linked to the N-terminus of an identical soluble domain or a distinct soluble domain of a biologically active protein. Also, the present invention discloses dimeric proteins formed by formation of intermolecular disulfide bonds at the hinge region of two monomeric proteins formed by linkage of a concatamer of two identical soluble extracellular regions of proteins involving immune response to an Fc fragment of an immunoglobulin molecule, their glycosylated proteins, DNA constructs encoding the monomeric proteins, recombinant expression plasmids containing the DNA construct, host cells transformed or transfected with the recombinant expression plasmids, and a method of preparing the dimeric proteins by culturing the host cells. Further, the present invention discloses pharmaceutical or diagnostic compositions comprising the dimeric protein or its glycosylated form.
    Type: Grant
    Filed: July 26, 2002
    Date of Patent: June 12, 2007
    Assignee: Medexgen Co., Ltd.
    Inventors: Yong-Hoon Chung, Ji-Woong Han, Hye-Ja Lee, Eun-Yong Choi, Jin-Mi Kim
  • Publication number: 20030195338
    Abstract: Disclosed are concatameric proteins comprising two soluble domains, in which the C-terminus of a soluble domain of a biologically active protein is linked to the N-terminus of an identical soluble domain or a distinct soluble domain of a biologically active protein. Also, the present invention discloses dimeric proteins formed by formation of intermolecular disulfide bonds at the hinge region of two monomeric proteins formed by linkage of a concatamer of two identical soluble extracellular regions of proteins involving immune response to an Fc fragment of an immunoglobulin molecule, their glycosylated proteins, DNA constructs encoding the monomeric proteins, recombinant expression plasmids containing the DNA construct, host cells transformed or transfected with the recombinant expression plasmids, and a method of preparing the dimeric proteins by culturing the host cells. Further, the present invention discloses pharmaceutical or diagnostic compositions comprising the dimeric protein or its glycosylated form.
    Type: Application
    Filed: February 28, 2003
    Publication date: October 16, 2003
    Inventors: Yong-Hoon Chung, Ji-Woong Han, Hye-Ja Lee, Eun-Yong Choi, Jin-Mi Kim