Patents by Inventor Hye-Ja Lee
Hye-Ja Lee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240000699Abstract: The present invention relates to a cosmetic composition including a Lycium chinense mill (“Goji berry”) fermented extract and/or green tea fermented extract, and a method for preparing the same. Specifically, there is provided a cosmetic composition with excellent antioxidant, wrinkle improvement and whitening effects, and a method for preparing the same.Type: ApplicationFiled: July 9, 2021Publication date: January 4, 2024Inventors: Hye-Ja LEE, Ji Hye KIM, Tae-Heon OH, Yun KIM, Jin Oh PARK
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Publication number: 20230173008Abstract: The present disclosure relates to a composition that is capable of preventing hair loss and promoting hair growth by comprising the extract of the above-ground part of carrots. The composition comprising the extract of the above-ground part of carrots of the present disclosure significantly increases the viability of dermal papilla cells and can inhibit the expression of 5a-reductase, thereby exhibiting excellent effects in preventing hair loss and promoting hair growth.Type: ApplicationFiled: July 16, 2021Publication date: June 8, 2023Inventors: Hyun Sook Yeom, Ji Hye Kim, Won Bo Oh, Hye JA Lee, Jin Oh Park, Ji Young Moon, Jeong Mi Kim, Byoung Kwon Park, Ji Won Lee
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Patent number: 11607437Abstract: The present invention relates to cosmetic and pharmaceutical compositions each containing a composite extract. More specifically, the present invention provides cosmetic and pharmaceutical compositions, each of which contains, as an active ingredient, a composite extract of an aloe extract and an upland rice extract, leading to excellent moisturizing, anti-inflammatory, and atopy alleviating effects, and thus can be favorably used for prevention, alleviation, and treatment of a skin disease.Type: GrantFiled: October 1, 2018Date of Patent: March 21, 2023Assignee: DAEBONG LS, LTDInventors: Jin-Oh Park, Ji-Won Lee, Hye-Ja Lee, Ji-Hye Kim, Won-Bo Oh
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Publication number: 20220378691Abstract: Provided is a cosmetic composition comprising a fermented product of Nuruk, and particularly, a cosmetic composition that can promote collagen synthesis in skin fibroblasts, have antioxidant effects and moisturizing effects, and prevent aging, comprising a fermented product of Nuruk obtained by fermenting grain with yeast mold (Aspergillus), as an active ingredient.Type: ApplicationFiled: April 11, 2022Publication date: December 1, 2022Inventors: Ji Hye Kim, Hyun Sook Yeom, Hye Ja Lee, Kyung Man Hahm, Jin Oh Park, Kyoung Hee Jang, Dae Hyun Shin, Ho An Kim, A Rang Kim, DaAe Park
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Publication number: 20220378688Abstract: The present disclosure relates to a moisturizing or anti-atopic composition, including a fatty acid or a fatty acid derivative. More specifically, the present disclosure relates to a moisturizing or anti-atopic composition including at least one compound selected from the group consisting of ethyl linoleate, ?-linolenic acid, and monolinolein as an active ingredient. The composition for moisturizing or anti-atopic dermatitis, according to the present disclosure, has not only low cytotoxicity but also an anti-inflammatory effect, an increase in the amount of moisturizing factor production, an increase in the amount of skin bather strengthening factor production, and an active effect to inhibit the production of atopic factors, so it can be used in various fields such as beauty for improving skin condition, pharmaceuticals, and food.Type: ApplicationFiled: November 2, 2020Publication date: December 1, 2022Inventors: Hyun Sook Yeom, Won Bo Oh, Hye JA Lee, Ji Hye Kim, Jeong Mi Kim, Ji Young Moon, Byoung Kwon Park, Jin Oh Park, Ji Won Lee, Nam Ho Lee, Jung Eun Kim
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Publication number: 20220370337Abstract: The present invention relates to a composition including a Tremella fuciformis culture medium extract. The Tremella fuciformis culture medium extract according to the present invention not only has low cytotoxicity but also has the effects of increasing the production amount of a moisturizing factor and the production amounts of collagen and collagen fibers and inhibiting in vivo active oxygen species, and thus can be utilized as a natural product-derived moisturizing, anti-wrinkle, and anti-oxidant functional material, and can be applied in various ways in the beauty and food fields for skin condition improvement.Type: ApplicationFiled: September 29, 2020Publication date: November 24, 2022Inventors: Hyun Sook Yeom, Won Bo Oh, Ji Hye Kim, Hye Ja Lee, Jin Oh Park, Ji Won Lee, Chul Ho Kim, Baek Rock Oh, Min Soo Kim, Sun Yeon Heo, Jeong Woo Seo
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Patent number: 11471390Abstract: Provided are a novel pseudoceramide compound and uses thereof. The pseudoceramide has antioxidant, anti-inflammatory, skin whitening, and moisturizing effects. In addition, the pseudoceramide can be synthesized in a simple and economically advantageous manner and is free from problems associated with the preparation of cosmetic formulations resulting from low hydrophilicity, thus being suitable for use in cosmetic applications.Type: GrantFiled: November 22, 2017Date of Patent: October 18, 2022Assignee: DAEBONG LS, LTDInventors: Jin Oh Park, Ji Won Lee, Seong Hyeon Jeon, Jae Young Lee, Hye Ja Lee, Bo Kyung Kwon
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Publication number: 20220023196Abstract: Provided is a cosmetic composition for skin improvement including a green barley extract.Type: ApplicationFiled: August 8, 2020Publication date: January 27, 2022Inventors: Kyung Rok LEE, Kyung Min KIM, Su Yeong KIM, Ji Mi KANG, So Young SHIN, Ji Hun PARK, Jin Oh PARK, Ji Won LEE, Hye Ja LEE, Ji Hye KIM, Ho Young KIM
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Publication number: 20200330350Abstract: Provided are a novel pseudoceramide compound and uses thereof. The pseudoceramide has antioxidant, anti-inflammatory, skin whitening, and moisturizing effects. In addition, the pseudoceramide can be synthesized in a simple and economically advantageous manner and is free from problems associated with the preparation of cosmetic formulations resulting from low hydrophilicity, thus being suitable for use in cosmetic applications.Type: ApplicationFiled: November 22, 2017Publication date: October 22, 2020Inventors: Jin Oh PARK, Ji Won LEE, Seong Hyeon JEON, Jae Young LEE, Hye Ja LEE, Bo Kyung KWON
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Publication number: 20200237848Abstract: The present invention relates to cosmetic and pharmaceutical compositions each containing a composite extract. More specifically, the present invention provides cosmetic and pharmaceutical compositions, each of which contains, as an active ingredient, a composite extract of an aloe extract and an upland rice extract, leading to excellent moisturizing, anti-inflammatory, and atopy alleviating effects, and thus can be favorably used for prevention, alleviation, and treatment of a skin disease.Type: ApplicationFiled: October 1, 2018Publication date: July 30, 2020Inventors: Jin-Oh Park, Ji-Won Lee, Hye-Ja Lee, Ji-Hye Kim, Won-Bo Oh
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Patent number: 10696623Abstract: The present invention relates to a novel phenolic acid derivative compound with whitening and antioxidant activities and use thereof. The phenolic acid derivative compound is a compound represented by Formula 1, which is described in the specification, an isomer thereof or a salt thereof. The compound of the present invention has skin whitening activity to inhibit tyrosinase, thus being suitable for use in a pharmaceutical composition or cosmetic product for skin whitening. In addition, the compound of the present invention is suitable for the prevention or treatment of oxidation-derived skin abnormality or disease such as skin aging due to its antioxidant activity.Type: GrantFiled: December 9, 2016Date of Patent: June 30, 2020Assignee: DAEBONG LS, LTDInventors: Jin Oh Park, Ji Won Lee, Jae Young Lee, Hye Ja Lee, Bo kyung Kwon
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Publication number: 20180362448Abstract: The present invention relates to a novel phenolic acid derivative compound with whitening and antioxidant activities and use thereof. The phenolic acid derivative compound is a compound represented by Formula 1, which is described in the specification, an isomer thereof or a salt thereof. The compound of the present invention has skin whitening activity to inhibit tyrosinase, thus being suitable for use in a pharmaceutical composition or cosmetic product for skin whitening. In addition, the compound of the present invention is suitable for the prevention or treatment of oxidation-derived skin abnormality or disease such as skin aging due to its antioxidant activity.Type: ApplicationFiled: December 9, 2016Publication date: December 20, 2018Inventors: Jin Oh PARK, Ji Won LEE, Jae Young LEE, Hye Ja LEE, Bo kyung KWON
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Patent number: 8372961Abstract: Disclosed are concatameric proteins comprising two soluble domains, in which the C-terminus of a soluble domain of a biologically active protein is linked to the N-terminus of an identical soluble domain or a distinct soluble domain of a biologically active protein. Also, the present invention discloses dimeric proteins formed by formation of intermolecular disulfide bonds at the hinge region of two monomeric proteins formed by linkage of a concatamer of two identical soluble extracellular regions of proteins involving immune response to an Fc fragment of an immunoglobulin molecule, their glycosylated proteins, DNA constructs encoding the monomeric proteins, recombinant expression plasmids containing the DNA construct, host cells transformed or transfected with the recombinant expression plasmids, and a method of preparing the dimeric proteins by culturing the host cells. Further, the present invention discloses pharmaceutical or diagnostic compositions comprising the dimeric protein or its glycosylated form.Type: GrantFiled: January 22, 2010Date of Patent: February 12, 2013Assignee: Medexgen Co., Ltd.Inventors: Yong-Hoon Chung, Ji-Woong Han, Hye-Ja Lee, Eun-Yong Choi, Jin-Mi Kim
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Publication number: 20100278827Abstract: Disclosed are concatameric proteins comprising two soluble domains, in which the C-terminus of a soluble domain of a biologically active protein is linked to the N-terminus of an identical soluble domain or a distinct soluble domain of a biologically active protein. Also, the present invention discloses dimeric proteins formed by formation of intermolecular disulfide bonds at the hinge region of two monomeric proteins formed by linkage of a concatamer of two identical soluble extracellular regions of proteins involving immune response to an Fc fragment pf an immunoglobulin molecule, their glycosylated proteins, DNA constructs encoding the monomeric proteins, recombinant expression plasmids containing the DNA construct, host cells transformed or transfected with the recombinant expression plasmids, and a method of preparing the dimeric proteins by culturing the host cells. Further, the present invention discloses pharmaceutical or diagnostic compositions comprising the dimeric protein or its glycosylated form.Type: ApplicationFiled: January 22, 2010Publication date: November 4, 2010Applicant: Medexgen Co., Ltd.Inventors: Yong-Hoon CHUNG, Ji-Woong Han, Hye-Ja Lee, Eun-Yong Choi, Jin-Mi Kim
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Patent number: 7670602Abstract: Disclosed are concatameric proteins comprising two soluble domains, in which the C-terminus of a soluble domain of a biologically active protein is linked to the N-terminus of an identical soluble domain or a distinct soluble domain of a biologically active protein. Also, the present invention discloses dimeric proteins formed by formation of intermolecular disulfide bonds at the hinge region of two monomeric proteins formed by linkage of a concatamer of two identical soluble extracellular regions of proteins involving immune response to an Fc fragment of an immunoglobulin molecule, their glycosylated proteins, DNA constructs encoding the monomeric proteins, recombinant expression plasmids containing the DNA construct, host cells transformed or transfected with the recombinant expression plasmids, and a method of preparing the dimeric proteins by culturing the host cells. Further, the present invention discloses pharmaceutical or diagnostic compositions comprising the dimeric protein or its glycosylated form.Type: GrantFiled: April 24, 2007Date of Patent: March 2, 2010Assignee: Medexgen Co., LtdInventors: Yong-Hoon Chung, Ji-Woong Han, Hye-Ja Lee, Eun-Yong Choi, Jin-Mi Kim
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Publication number: 20090011466Abstract: Disclosed are concatameric proteins comprising two soluble domains, in which the C-terminus of a soluble domain of a biologically active protein is linked to the N-terminus of an identical soluble domain or a distinct soluble domain of a biologically active protein. Also, the present invention discloses dimeric proteins formed by formation of intermolecular disulfide bonds at the hinge region of two monomeric proteins formed by linkage of a concatamer of two identical soluble extracellular regions of proteins involving immune response to an Fc fragment of an immunoglobulin molecule, their glycosylated proteins, DNA constructs encoding the monomeric proteins, recombinant expression plasmids containing the DNA construct, host cells transformed or transfected with the recombinant expression plasmids, and a method of preparing the dimeric proteins by culturing the host cells. Further, the present invention discloses pharmaceutical or diagnostic compositions comprising the dimeric protein or its glycosylated form.Type: ApplicationFiled: April 24, 2007Publication date: January 8, 2009Applicant: MEDEXGEN CO., LTD.Inventors: Yong-Hoon CHUNG, Ji-Woong HAN, Hye-Ja LEE, Eun-Yong CHOI, Jin-Mi KIM
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Patent number: 7229962Abstract: Disclosed are concatameric proteins comprising two soluble domains, in which the C-terminus of a soluble domain of a biologically active protein is linked to the N-terminus of an identical soluble domain or a distinct soluble domain of a biologically active protein. Also, the present invention discloses dimeric proteins formed by formation of intermolecular disulfide bonds at the hinge region of two monomeric proteins formed by linkage of a concatamer of two identical soluble extracellular regions of proteins involving immune response to an Fc fragment of an immunoglobulin molecule, their glycosylated proteins, DNA constructs encoding the monomeric proteins, recombinant expression plasmids containing the DNA construct, host cells transformed or transfected with the recombinant expression plasmids, and a method of preparing the dimeric proteins by culturing the host cells. Further, the present invention discloses pharmaceutical or diagnostic compositions comprising the dimeric protein or its glycosylated form.Type: GrantFiled: July 26, 2002Date of Patent: June 12, 2007Assignee: Medexgen Co., Ltd.Inventors: Yong-Hoon Chung, Ji-Woong Han, Hye-Ja Lee, Eun-Yong Choi, Jin-Mi Kim
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Publication number: 20030195338Abstract: Disclosed are concatameric proteins comprising two soluble domains, in which the C-terminus of a soluble domain of a biologically active protein is linked to the N-terminus of an identical soluble domain or a distinct soluble domain of a biologically active protein. Also, the present invention discloses dimeric proteins formed by formation of intermolecular disulfide bonds at the hinge region of two monomeric proteins formed by linkage of a concatamer of two identical soluble extracellular regions of proteins involving immune response to an Fc fragment of an immunoglobulin molecule, their glycosylated proteins, DNA constructs encoding the monomeric proteins, recombinant expression plasmids containing the DNA construct, host cells transformed or transfected with the recombinant expression plasmids, and a method of preparing the dimeric proteins by culturing the host cells. Further, the present invention discloses pharmaceutical or diagnostic compositions comprising the dimeric protein or its glycosylated form.Type: ApplicationFiled: February 28, 2003Publication date: October 16, 2003Inventors: Yong-Hoon Chung, Ji-Woong Han, Hye-Ja Lee, Eun-Yong Choi, Jin-Mi Kim