Abstract: The present invention relates to a multi-conjugate of small interfering RNA (siRNA) and a preparing method of the same, more precisely a multi-conjugate of siRNA prepared by direct binding of double stranded sense/antisense siRNA monomers or indirect covalent bonding mediated by a cross-linking agent or a polymer, and a preparing method of the same. The preparing method of a siRNA multi-conjugate of the present invention is characterized by simple and efficient reaction and thereby the prepared siRNA multi-conjugate of the present invention has high molecular weight multiple times the conventional siRNA, so that it has high negative charge density, suggesting that it has excellent ionic interaction with a cationic gene carrier and high gene delivery efficiency.

Abstract: An ethylene/alpha-olefin copolymer having excellent physical properties showing reduced immersion time of a crosslinking agent and a high degree of crosslinking, and a composition for an encapsulant film, comprising the same, is described herein.

Abstract: A method performed by a managing server includes: receiving, from an electronic device, operation data of the electronic device; identifying, by using artificial intelligence (AI), a device usage pattern of the electronic device; identifying, by using the AI, information related to a failure or an abnormal operation of the electronic device and a solution to the failure or the abnormal operation based on the device usage pattern and the operation data received from the electronic device; and transmitting, to a user terminal, the information related to the failure or the abnormal operation of the electronic device and the solution to the failure or the abnormal operation.

Abstract: The present disclosure relates to a fixing cap assembly and a pipe fitting including same. The fixing cap assembly according to an embodiment of The present disclosure comprises: a fixing cap fastened to a connection portion of a main body, to which at least one pipe is connected, and fixing the main body and the pipe to each other; a washer which is positioned inside the fixing cap and compresses a sealing member (120), interposed between the main body and the pipe, as the fixing cap is fastened, and of which the diameter contracts and is restored in the radial direction; and a coupling member including a plurality of tooth-shaped protrusions which protrude radially from the inner circumferential surface of the washer toward the outer circumferential surface of the pipe and press the outer circumferential surface of the pipe as the washer contracts, thereby fixing the pipe.

Abstract: A pipe-fitting includes a plurality of pipe receiving portions, a hollow joint for connecting the plurality of pipe receiving portions to each other, a sealing member received in a sealing member-receiving groove, and a plurality of hollow fixing-caps, wherein each fixing-cap is screwed to a distal end of each pipe receiving portion to press the sealing member to be brought into close contact with each pipe. A fixing-cap stopper is formed on an outer circumferential face of each pipe receiving portion. The fixing-cap stopper includes a fixing-cap fixing portion including a plurality of fixing protrusions protruding toward a proximal end of the fixing-cap. A plurality of fixing-protrusion-receiving grooves is defined in the proximal end of each fixing-cap for receiving the fixing-protrusions therein respectively.

Abstract: The present invention relates to a reduced-graphene-oxide/silicon-metal-particle composite, a method of manufacturing the composite and an electrode for a secondary battery including the composite. The method of manufacturing the reduced-graphene-oxide/silicon-metal-particle composite includes preparing a reduced-graphene-oxide dispersion solution by reducing graphene oxide formed through cation-pi interaction, preparing a reduced-graphene-oxide/silicon-metal-particle dispersion solution by mixing the reduced-graphene-oxide dispersion solution with silicon metal particles, and manufacturing a composite powder having a core-shell structure by drying the reduced-graphene-oxide/silicon-metal-particle dispersion solution. Thereby, reduced graphene oxide can be formed using the graphene oxide dispersion solution having few defects and high purity obtained through cation-pi interaction, and dried to afford a composite powder having a core-shell structure, which is applicable to an electrode for a secondary battery.

Abstract: The present invention is related to a parallel line biochip for multiplex diagnosis. The parallel line biochip for multiplex diagnosis includes a plurality of line strips disposed in parallel, and a well configured to immobilize the line strips. Since the parallel line biochip for multiplex diagnosis can be used to connect two or more line strips in parallel, the parallel line biochip for multiplex diagnosis has an effect of measuring various materials present in a biological test sample at the same time.

Abstract: A pipe-fitting includes a plurality of pipe receiving portions, a hollow joint for connecting the plurality of pipe receiving portions to each other, a sealing member received in a sealing member-receiving groove, and a plurality of hollow fixing-caps, wherein each fixing-cap is screwed to a distal end of each pipe receiving portion to press the sealing member to be brought into close contact with each pipe. A fixing-cap stopper is formed on an outer circumferential face of each pipe receiving portion. The fixing-cap stopper includes a fixing-cap fixing portion including a plurality of fixing protrusions protruding toward a proximal end of the fixing-cap. A plurality of fixing-protrusion-receiving grooves is defined in the proximal end of each fixing-cap for receiving the fixing-protrusions therein respectively.

Abstract: Provided are an autoantibody specifically binding to an exosomal protein EIF3A (Eukaryotic translation initiation factor 3 subunit A) or a fragment including an antigen-binding site (paratope) thereof, a hybridoma cell line producing the autoantibody, a polypeptide having an amino acid sequence of an antigenic determinant (epitope) specifically binding to the autoantibody, a composition for diagnosing liver cancer including an agent measuring an expression level of the autoantibody or the fragment including the antigen-binding site thereof, a kit for diagnosing liver cancer including the composition, and a method of providing information for diagnosis of liver cancer by using the composition. Further, provided is a method of screening for a therapeutic agent for liver cancer by using an expression level of the autoantibody.

Abstract: The present invention relates to a reduced-graphene-oxide/silicon-metal-particle composite, a method of manufacturing the composite and an electrode for a secondary battery including the composite. The method of manufacturing the reduced-graphene-oxide/silicon-metal-particle composite includes preparing a reduced-graphene-oxide dispersion solution by reducing graphene oxide formed through cation-pi interaction, preparing a reduced-graphene-oxide/silicon-metal-particle dispersion solution by mixing the reduced-graphene-oxide dispersion solution with silicon metal particles, and manufacturing a composite powder having a core-shell structure by drying the reduced-graphene-oxide/silicon-metal-particle dispersion solution. Thereby, reduced graphene oxide can be formed using the graphene oxide dispersion solution having few defects and high purity obtained through cation-pi interaction, and dried to afford a composite powder having a core-shell structure, which is applicable to an electrode for a secondary battery.

Abstract: Provided are an autoantibody specifically binding to an exosomal protein EIF3A (Eukaryotic translation initiation factor 3 subunit A) or a fragment including an antigen-binding site (paratope) thereof, a hybridoma cell line producing the autoantibody, a polypeptide having an amino acid sequence of an antigenic determinant (epitope) specifically binding to the autoantibody, a composition for diagnosing liver cancer including an agent measuring an expression level of the autoantibody or the fragment including the antigen-binding site thereof, a kit for diagnosing liver cancer including the composition, and a method of providing information for diagnosis of liver cancer by using the composition. Further, provided is a method of screening for a therapeutic agent for liver cancer by using an expression level of the autoantibody.

Abstract: A flexible secondary battery includes an electrode assembly, a first external cover that is located on a first surface of the electrode assembly, and a second external cover that is located on a second surface of the electrode assembly, the second external cover and the first external cover including a sealing portion where edges of the first external cover and the second external cover are attached to each other to seal the electrode assembly. At least one of the first external cover and the second external cover includes a stress-relief pattern in a center portion.