Patents by Inventor Hye Kyung Ju

Hye Kyung Ju has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Recombinant expression vector for animal cell
    Patent number: 8426570
    Abstract: The present invention relates to a recombinant expression vector for an animal cell containing a dihydrofolate reductase (DHFR) coding nucleotide sequence operatively linked to a DHFR promoter, to an animal cell line transformed by the vector, and to a method for preparing a target protein using the same. As compared with existing animal cell expression vectors, the vector of the present invention enables an effective screening of a cell line clone in which foreign genes are amplified together with DHFR genes even at a much lower methotrexate concentration. The present invention exhibits excellent effects in cell line preparation as high-productivity cell lines can be ensured in a short time through the use of a lower concentration of methotrexate in the process of protein production cell line establishment.
    Type: Grant
    Filed: July 7, 2009
    Date of Patent: April 23, 2013
    Assignee: Aprogen Inc.
    Inventors: Keun Soo Kim, Hye Kyung Ju, Choon Ju Jeon, Jae Seob Kim
  • Recombinant Expression Vector for Animal Cell
    Publication number: 20110117643
    Abstract: The present invention relates to a recombinant expression vector for an animal cell containing a dihydrofolate reductase (DHFR) coding nucleotide sequence operatively linked to a DHFR promoter, to an animal cell line transformed by the vector, and to a method for preparing a target protein using the same. As compared with existing animal cell expression vectors, the vector of the present invention enables an effective screening of a cell line clone in which foreign genes are amplified together with DHFR genes even at a much lower methotrexate concentration. The present invention exhibits excellent effects in cell line preparation as high-productivity cell lines can be ensured in a short time through the use of a lower concentration of methotrexate in the process of protein production cell line establishment.
    Type: Application
    Filed: July 7, 2009
    Publication date: May 19, 2011
    Applicant: Aprogen Inc.
    Inventors: Keun Soo Kim, Hye Kyung Ju, Choon Ju Jeon, Jae Seob Kim
  • Method for inhibiting 5-lipoxygenase using a benzoxazole derivative
    Patent number: 7329682
    Abstract: A benzoxazole derivative is disclosed for inhibiting 5-lipoxygenase.
    Type: Grant
    Filed: February 27, 2004
    Date of Patent: February 12, 2008
    Assignee: EWHA University-Industry Collaboration Foundation
    Inventors: Hea Young Park Choo, Hyeun Wook Chang, Ju Hee Yoon, Hye Kyung Ju
  • Method for inhibiting 5-lipoxygenase using a benzoxazole derivative or an analogue thereof
    Publication number: 20040198768
    Abstract: Use of a benzoxazole derivative or an analogue thereof inhibits 5-lipoxygenase in a subject.
    Type: Application
    Filed: February 27, 2004
    Publication date: October 7, 2004
    Inventors: Hea Young Park Choo, Hyeun Wook Chang, Ju Hee Yoon, Hye Kyung Ju