Abstract: A method and apparatus for predicting a recipe property reflecting similarity between chemical materials are provided. The method of predicting a recipe property reflecting similarity between chemical materials, the method includes substituting a plurality of input materials with vector data, respectively, through material embedding and generating recipe data including pieces of vector data selected by considering a correlation between materials, and inputting the recipe data to an artificial neural network (ANN) prediction model and deriving a property prediction result on the recipe data from the ANN prediction model.

Abstract: A compound of Chemical Formula 1, and an organic photoelectric device, an image sensor, and an electronic device including the same are disclosed: In Chemical Formula 1, the definition of each group and parameter is as described in the detailed description.

Abstract: A method of fabricating a semiconductor device is provided. The method includes: loading a substrate into a substrate processing apparatus; and processing the substrate, using the substrate processing apparatus. The processing the substrate includes: providing a process gas; generating a process etchant from the process gas, using plasma ignition, the process etchant including a first etchant and a second etchant; processing the substrate, using the process etchant; identifying a composition rate of the process etchant; and controlling the processing of the substrate based on a process result according to the composition rate of the process etchant.

Abstract: An apparatus for non-invasively estimating bio-information and a method of determining whether a bio-signal is normal by the apparatus for estimating bio-information are provided. The apparatus for estimating bio-information according to an embodiment of the disclosure includes: a photoplethysmogram (PPG) sensor configured to measure a PPG signal from an object; and a processor configured to extract a plurality of pairs of local maximum points and local minimum points from a second derivative signal of the PPG signal, to select at least one reference pair from among the extracted plurality of pairs, and to determine whether the PPG signal is normal based on the selected at least one reference pair.

Abstract: The present disclosure relates to a composition for preventing, improving or treating a metabolic syndrome such as obesity, diabetes, hyperlipidemia and fatty liver, comprising a combination of a Lemon balm extract and a corn silk extract as a natural extract as an active ingredient.

Abstract: The present invention relates to a heteroaryl derivative compound and a use thereof. Since the heteroaryl derivative of the present invention exhibits excellent inhibitory activity against EGFR, the heteroaryl derivative can be usefully used as a therapeutic agent for EGFR-associated diseases.

Abstract: An apparatus for non-invasively measuring bio-information is provided. The apparatus for estimating bio-information may include a pulse wave sensor configured to measure a pulse wave signal from an object; a sensor position sensor configured to obtain sensor position information of the pulse wave sensor with respect to the object, based on the object being in contact with the pulse wave sensor; and a processor configured to estimate the bio-information based on blood vessel position information of the object, the sensor position information, and the pulse wave signal.

Abstract: The present disclosure relates to a cancer-specific trans-splicing ribozyme and a use thereof. The trans-splicing ribozyme does not act on normal tissues but is specifically expressed in cancer tissues, and thus the safety thereof is high and the expression efficiency thereof is excellent at the post-transcription level, and one or more target genes are connected to the 3? exon of the ribozyme so that a cancer therapeutic gene and an immune checkpoint inhibitor are expressed together when applied in vivo, and thus the present disclosure can be effectively used in cancer treatment.

Abstract: The present invention relates to a resin composition including a binder resin and an organic-inorganic composite filler, a prepreg including the same, a laminated plate including the same, and a resin-coated metal foil including the same.

Abstract: The present invention relates to a composition for preventing and treating osteoarthritis, which contains a pomegranate concentrate, a eucommia bark extract and an achyranthis radix extract as active ingredients. More specifically, the composite composition of a pomegranate concentrate, a eucommia bark extract and an achyranthis radix extract according to the present invention has a synergistic effect of improving osteoarthritis. In particular, because it can directly protect and regenerate the cartilage and can improve joint stiffness, it can be used in health food, etc.

Abstract: To efficiently analyze interaction and function between proteins, the present invention relates to a method for forming a light-induced protein nanocluster, comprising: an expression vector preparation step of preparing a first expression vector including polynucleotides coding a first fusion protein including a light-induced heterodimer-forming protein and a first self-assembly protein, and a second expression vector including polynucleotides coding a couple protein that forms a homodimer with said light-induced heterodimer-forming protein, or a second fusion protein including said couple protein and a second self-assembly protein; a transformed cell, tissue or individual preparation step of transforming cells, tissues or individuals using said first expression vector and second expression vector; and a light radiation step of radiating light having a wavelength for inducing the formation of heterodimer between said light-induced heterodimer-forming protein and said couple protein, to said transformed cells,

Abstract: The present invention relates to a composition for preventing and treating osteoarthritis, which contains a pomegranate concentrate, a eucommia bark extract and an achyranthis radix extract as active ingredients. More specifically, the composite composition of a pomegranate concentrate, a eucommia bark extract and an achyranthis radix extract according to the present invention has a synergistic effect of improving osteoarthritis. In particular, because it can directly protect and regenerate the cartilage and can improve joint stiffness, it can be used in health food, etc.

Abstract: The present invention relates to a method for preventing, improving or treating a periodontal disease, by administering a composition containing a moringa extract and a eucommia bark extract as active ingredients. More specifically, the complex composition of a moringa extract and a eucommia bark extract according to the present invention provides a synergistic effect in improvement of a periodontal disease including gingivitis and periodontitis. Especially, it exhibits an effect of directly preventing or improving a periodontal disease through antioxidant, antibacterial or anti-inflammatory effect, improvement of alveolar bone loss and regeneration of alveolar bone, etc. Accordingly, it can be usefully used as a food, a medicine, a quasi-drug, etc.

Abstract: The present invention relates to a method for preventing, improving or treating a periodontal disease, by administering a composition containing a moringa extract and a eucommia bark extract as active ingredients. More specifically, the complex composition of a moringa extract and a eucommia bark extract according to the present invention provides a synergistic effect in improvement of a periodontal disease including gingivitis and periodontitis. Especially, it exhibits an effect of directly preventing or improving a periodontal disease through antioxidant, antibacterial or anti-inflammatory effect, improvement of alveolar bone loss and regeneration of alveolar bone, etc. Accordingly, it can be usefully used as a food, a medicine, a quasi-drug, etc.

Abstract: To efficiently analyze interaction and function between proteins, the present invention relates to a method for forming a light-induced protein nanocluster, comprising: an expression vector preparation step of preparing a first expression vector including polynucleotides coding a first fusion protein including a light-induced heterodimer-forming protein and a first self-assembly protein, and a second expression vector including polynucleotides coding a couple protein that forms a homodimer with said light-induced heterodimer-forming protein, or a second fusion protein including said couple protein and a second self-assembly protein; a transformed cell, tissue or individual preparation step of transforming cells, tissues or individuals using said first expression vector and second expression vector; and a light radiation step of radiating light having a wavelength for inducing the formation of heterodimer between said light-induced heterodimer-forming protein and said couple protein, to said transformed cells,

Abstract: To efficiently analyze interaction and function between proteins, the present invention relates to a method for forming a light-induced protein nanocluster, comprising: an expression vector preparation step of preparing a first expression vector including polynucleotides coding a first fusion protein including a light-induced heterodimer-forming protein and a first self-assembly protein, and a second expression vector including polynucleotides coding a couple protein that forms a homodimer with said light-induced heterodimer-forming protein, or a second fusion protein including said couple protein and a second self-assembly protein; a transformed cell, tissue or individual preparation step of transforming cells, tissues or individuals using said first expression vector and second expression vector; and a light radiation step of radiating light having a wavelength for inducing the formation of heterodimer between said light-induced heterodimer-forming protein and said couple protein, to said transformed cells,

Abstract: To efficiently analyze interaction and function between proteins, the present invention relates to a method for forming a light-induced protein nanocluster, comprising: an expression vector preparation step of preparing a first expression vector including polynucleotides coding a first fusion protein including a light-induced heterodimer-forming protein and a first self-assembly protein, and a second expression vector including polynucleotides coding a couple protein that forms a homodimer with said light-induced heterodimer-forming protein, or a second fusion protein including said couple protein and a second self-assembly protein; a transformed cell, tissue or individual preparation step of transforming cells, tissues or individuals using said first expression vector and second expression vector; and a light radiation step of radiating light having a wavelength for inducing the formation of heterodimer between said light-induced heterodimer-forming protein and said couple protein, to said transformed cells,

Abstract: A method of fabricating a semiconductor device, the method including forming a buffer oxide layer in a first region and a second region of a semiconductor substrate; forming a plurality of first preliminary mask patterns on the buffer oxide layer in the first region; forming a plurality of second preliminary mask patterns between every two adjacent first preliminary mask patterns from among the plurality of first preliminary mask patterns, respectively; forming a plurality of first mask patterns and a plurality of second mask patterns by trimming the plurality of first preliminary mask patterns and the plurality of second preliminary mask patterns; forming a plurality of first active region mask patterns for exposing the semiconductor substrate; defining a plurality of active regions in the semiconductor substrate by forming a trench including a plurality of first trench spaces having same width as the first space and a plurality of second trench spaces under the second space in the first region; and forming

Abstract: A method of fabricating a semiconductor device, the method including forming a buffer oxide layer in a first region and a second region of a semiconductor substrate; forming a plurality of first preliminary mask patterns on the buffer oxide layer in the first region; forming a plurality of second preliminary mask patterns between every two adjacent first preliminary mask patterns from among the plurality of first preliminary mask patterns, respectively; forming a plurality of first mask patterns and a plurality of second mask patterns by trimming the plurality of first preliminary mask patterns and the plurality of second preliminary mask patterns; forming a plurality of first active region mask patterns for exposing the semiconductor substrate; defining a plurality of active regions in the semiconductor substrate by forming a trench including a plurality of first trench spaces having same width as the first space and a plurality of second trench spaces under the second space in the first region; and forming