Abstract: Disclosed is an electrochemical device separator and an electrochemical device including the same. The separator includes a porous polymer substrate and a porous organic/inorganic composite coating layer formed on at least one surface of the polymer substrate, in which the porous coating layer includes particulate binder resins and inorganic particles, and [content of binder particles in an upper portion of a porous coating layer before impregnation with electrolyte/content of binder particles in a central portion of a porous coating layer before impregnation with electrolyte]?[content of binder particles in an upper portion of a porous coating layer after impregnation with electrolyte/content of binder particles in a central portion of a porous coating layer after impregnation with electrolyte] is 0.32 or less.

Abstract: Disclosed herein a method of constructing a blood vessel map, the method including: receiving, by a blood vessel map construction apparatus, a TOF image of the object; extracting, by the blood vessel map construction apparatus, a blood vessel stem, a center line of a blood vessel, and features of the center line included in the TOF image, and detecting branch points of the blood vessel based on the extracted blood vessel stem, center line of the blood vessel, and features of the center line; searching, by the blood vessel map construction apparatus, a reference blood vessel image corresponding to the TOF image in consideration of location information or curvature information of the branch points; calculating a similarity between the TOF image and the reference blood vessel image; and registering the TOF image in the blood vessel map based on the similarity.

Abstract: Provided are a method for predicting a treatment response to cancer immunotherapy, the method comprising a step of evaluating, from feces isolated from a patient, the enrichment of a strain of the order TANB77 according to GTDB phylogenetic classification or taxa belonging to the order TANB77, and a step of predicting a treatment response of the patient to cancer immunotherapy on the basis of the enrichment of the order TANB77 or the taxa; a probiotics composition for improving a treatment response; a fecal microbiota transplantation composition; and a method for screening for candidate prebiotics by using same.

Abstract: The present specification provides a method for providing information about a therapeutic response to anticancer immunotherapy, and a kit for providing information by using same, the method comprising: measuring DNA methylation of pDMRs in a biological sample isolated from a subject; and evaluating the therapeutic reaction to anticancer immunotherapy for the subject on the basis of the measured DNA methylation of pDMRs.

Abstract: Disclosed herein a method of constructing a blood vessel map, the method including: receiving, by a blood vessel map construction apparatus, a TOF image of the object; extracting, by the blood vessel map construction apparatus, a blood vessel stem, a center line of a blood vessel, and features of the center line included in the TOF image, and detecting branch points of the blood vessel based on the extracted blood vessel stem, center line of the blood vessel, and features of the center line; searching, by the blood vessel map construction apparatus, a reference blood vessel image corresponding to the TOF image in consideration of location information or curvature information of the branch points; calculating a similarity between the TOF image and the reference blood vessel image; and registering the TOF image in the blood vessel map based on the similarity.

Abstract: Provided in the present disclosure are a method for providing information on a therapeutic reaction of cancer immunotherapy and a kit using same for providing information, the method comprising the steps of: measuring respective expression levels of PD-L1 and PVR in a biological sample isolated from a subject; and evaluating the therapeutic reaction of cancer immunotherapy for the subject on the basis of the measured expression levels of PD-L1 and PVR.

Abstract: The present disclosure relates to a novel use of EI24, and provides a novel use of EI24 involved in the improvement of EGFR-TKI drug resistance by inhibiting IGF-1R signaling. According to the present disclosure, the presence or absence of resistance to anti-cancer drugs may be determined by detecting an expression level of EI24. In addition, resistance to anti-cancer drugs may be inhibited, delayed, or improved using EI24 or an activating agent thereof. Moreover, by regulating a pathway of EI24-mediated resistance to anti-cancer drugs, the efficacy of existing anti-cancer drugs may be enhanced, and resistance to anti-cancer drugs may be inhibited, delayed, or improved.

Abstract: The present disclosure relates to a novel use of EI24, and provides a novel use of EI24 involved in the improvement of EGFR-TKI drug resistance by inhibiting IGF-1R signaling. According to the present disclosure, the presence or absence of resistance to anti-cancer drugs may be determined by detecting an expression level of EI24. In addition, resistance to anti-cancer drugs may be inhibited, delayed, or improved using EI24 or an activating agent thereof. Moreover, by regulating a pathway of EI24-mediated resistance to anti-cancer drugs, the efficacy of existing anti-cancer drugs may be enhanced, and resistance to anti-cancer drugs may be inhibited, delayed, or improved.

Abstract: In a method of manufacturing a semiconductor device, a blend solution that includes a block copolymer and an adsorbent is prepared. The block copolymer is synthesized by a copolymerization between a first polymer unit and a second polymer unit having a hydrophilicity greater than that of the first polymer unit. The adsorbent on which the block copolymer is adsorbed is extracted. The block copolymer is separated from the adsorbent. The block copolymer is collected. The block copolymer may be used to form a mask on an object layer on a substrate and the mask used to etch the object layer.

Abstract: In a method of manufacturing a semiconductor device, a blend solution that includes a block copolymer and an adsorbent is prepared. The block copolymer is synthesized by a copolymerization between a first polymer unit and a second polymer unit having a hydrophilicity greater than that of the first polymer unit. The adsorbent on which the block copolymer is adsorbed is extracted. The block copolymer is separated from the adsorbent. The block copolymer is collected. The block copolymer may be used to form a mask on an object layer on a substrate and the mask used to etch the object layer.