Patents by Inventor Hye Seong LIM

Hye Seong LIM has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220096589
    Abstract: A treatment of cervical tumor caused by human papillomavirus (HPV) infection is disclosed. Methods for improving treatment of cervical tumor caused by HPV infection are also disclosed. The methods include administering a polynucleotide encoding an E6/E7 fusion protein to a subject suffering from cervical tumor caused by HPV. The cervical tumor may be squamous cell carcinoma (SCC), adenocarcinoma, adenosquamous carcinoma, small cell carcinoma, neuroendocrine tumor (NET), glassy cell carcinoma, villoglandular adenocarcinoma (VGA), non-carcinoma malignancies, melanoma, lymphoma, or cervical intraepithelial neoplasia (CIN).
    Type: Application
    Filed: August 27, 2021
    Publication date: March 31, 2022
    Applicant: GENEXINE, INC.
    Inventors: Hyun-Tak JIN, Hye Seong LIM, You Suk SUH, Eun Joo NAM
  • Patent number: 11135262
    Abstract: This invention relates to the treatment of cervical tumor caused by human papillomavirus (HPV) infection. In particular, the invention provides methods for improving cervical tumor treatment and methods for treating cervical tumor caused by HPV infection using a polynucleotide encoding an E6/E7 fusion protein.
    Type: Grant
    Filed: August 14, 2015
    Date of Patent: October 5, 2021
    Assignee: GENEXINE, INC.
    Inventors: Hyun-Tak Jin, Hye Seong Lim, You Suk Suh, Eun Joo Nam
  • Patent number: 11041007
    Abstract: The present invention provides a modified interleukin-7 and a use thereof. The modified IL-7 or an IL-7 fusion protein of the present invention comprising the same can be obtained in high yield, and biologically active in viral infection and cancer models. Therefore, they can be used for the prevention and treatment of various diseases.
    Type: Grant
    Filed: December 13, 2018
    Date of Patent: June 22, 2021
    Assignee: GENEXINE, INC.
    Inventors: Se Hwan Yang, Donghoon Choi, Hye Seong Lim
  • Patent number: 10844104
    Abstract: The present invention provides a modified interleukin-7 and a use thereof. The modified IL-7 or an IL-7 fusion protein of the present invention comprising the same can be obtained in high yield, and biologically active in viral infection and cancer models. Therefore, they can be used for the prevention and treatment of various diseases.
    Type: Grant
    Filed: June 5, 2018
    Date of Patent: November 24, 2020
    Assignee: GENEXINE, INC.
    Inventors: Se Hwan Yang, Donghoon Choi, Hye Seong Lim
  • Publication number: 20190106471
    Abstract: The present invention provides a modified interleukin-7 and a use thereof. The modified IL-7 or an IL-7 fusion protein of the present invention comprising the same can be obtained in high yield, and biologically active in viral infection and cancer models. Therefore, they can be used for the prevention and treatment of various diseases.
    Type: Application
    Filed: December 13, 2018
    Publication date: April 11, 2019
    Applicant: GENEXINE, INC
    Inventors: Se Hwan YANG, Donghoon CHOI, Hye Seong LIM
  • Patent number: 10208099
    Abstract: The present invention provides a modified interleukin-7 and a use thereof. The modified IL-7 or an IL-7 fusion protein of the present invention comprising the same can be obtained in high yield, and biologically active in viral infection and cancer models. Therefore, they can be used for the prevention and treatment of various diseases.
    Type: Grant
    Filed: June 10, 2016
    Date of Patent: February 19, 2019
    Assignee: GENEXINE, INC.
    Inventors: Se Hwan Yang, Donghoon Choi, Hye Seong Lim
  • Publication number: 20180273596
    Abstract: The present invention provides a modified interleukin-7 and a use thereof. The modified IL-7 or an IL-7 fusion protein of the present invention comprising the same can be obtained in high yield, and biologically active in viral infection and cancer models. Therefore, they can be used for the prevention and treatment of various diseases.
    Type: Application
    Filed: June 5, 2018
    Publication date: September 27, 2018
    Applicant: GENEXINE, INC.
    Inventors: Se Hwan YANG, Donghoon CHOI, Hye Seong LIM
  • Publication number: 20170304385
    Abstract: This invention relates to the treatment of cervical tumor caused by human papillomavirus (HPV) infection. In particular, the invention provides methods for improving cervical tumor treatment and methods for treating cervical tumor caused by HPV infection using a polynucleotide encoding an E6/E7 fusion protein.
    Type: Application
    Filed: August 14, 2015
    Publication date: October 26, 2017
    Applicant: GENEXINE, Inc.
    Inventors: Hyun-Tak JIN, HYE SEONG LIM, YOU SUK SUH, EUN JOO NAM
  • Publication number: 20170189476
    Abstract: The present invention relates to a fusion protein composed of the extracellular domain of PD-L1 and a modified immunoglobulin Fc region. The extracellular domain of PD-L1 and a fragment thereof have excellent immunomodulatory activity, and can be used as an immunomodulatory agent if a modified immunoglobulin Fc region is coupled thereto. Accordingly, the PD-L1 fusion protein according to the present invention demonstrated its excellent effect in disease models of inflammatory bowel disease, colitis, psoriasis, asthma and arthritis, and thus can be very effectively used for the treatment of such diseases.
    Type: Application
    Filed: May 26, 2015
    Publication date: July 6, 2017
    Applicants: GENEXINE, INC., POSTECH ACADEMY-INDUSTRY FOUNDATION
    Inventors: Young Chul SUNG, Ji Yeung LEE, Mi-Young SONG, Hye Seong LIM, Byung Ha LEE
  • Publication number: 20170158746
    Abstract: The present invention provides a modified interleukin-7 and a use thereof. The modified IL-7 or an IL-7 fusion protein of the present invention comprising the same can be obtained in high yield, and biologically active in viral infection and cancer models. Therefore, they can be used for the prevention and treatment of various diseases.
    Type: Application
    Filed: June 10, 2016
    Publication date: June 8, 2017
    Applicant: Genexine, Inc.
    Inventors: Se Hwan YANG, Donghoon CHOI, Hye Seong LIM