Patents by Inventor Hye Won Um

Hye Won Um has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200002686
    Abstract: Disclosed is a modified microorganism producing putrescine or ornithine, and a method for producing putrescine or ornithine using the same.
    Type: Application
    Filed: July 10, 2019
    Publication date: January 2, 2020
    Inventors: Su Jin PARK, Young Lyeol YANG, Hye Won UM, Hong Xian LI, Kyoung Min LEE, Baek Seok LEE, Hyo Hyoung LEE, Hee Kyoung JUNG
  • Patent number: 10450262
    Abstract: A method for purifying 1,4-diaminobutane comprising the steps of: separating a second composition including carbonate salt of 1,4-diaminobutane from a first composition including carbonate salt of 1,4-diaminobutane by distillation; and removing carbonate from carbonate salt of 1,4-diaminobutane included in the second composition to recover 1,4-diaminobutane.
    Type: Grant
    Filed: May 4, 2016
    Date of Patent: October 22, 2019
    Assignee: CJ CHEILJEDANG CORPORATION
    Inventors: Won Sik Gwak, Hong Xian Li, Hyun Ju Won, Hyo Hyoung Lee, Kyung Su Na, Su Jin Park, Young Lyeol Yang, Hye Won Um, Chang Yub Oh, Kyoung Min Lee
  • Patent number: 10316339
    Abstract: The present invention relates to a polypeptide having a resistant to feedback inhibition by methionine and an activity of homoserine O-succinyltransferase, a O-succinyl homoserine-producing microorganism expressing the polypeptide, and a method for producing O-succinyl homoserine using the same.
    Type: Grant
    Filed: October 22, 2014
    Date of Patent: June 11, 2019
    Assignee: CJ CHEILJEDANG CORPORATION
    Inventors: Su Jin Choi, So Young Kim, Chang Il Seo, Yong Uk Shin, Young Lyeol Yang, Hye Won Um, Hye Min Park, Sung Hoo Jhon, Byung Hoon Jung
  • Publication number: 20190136274
    Abstract: The present invention relates to a recombinant microorganism capable of producing putrescine, in which the microorganism is modified to have enhanced NCgl2522 activity, thereby producing putrescine in a high yield, and a method for producing putrescine using the microorganism.
    Type: Application
    Filed: January 11, 2019
    Publication date: May 9, 2019
    Applicant: CJ CHEILJEDANG CORPORATION
    Inventors: Kyoung Min LEE, Hee Kyoung JUNG, Young Lyeol YANG, Hye Won UM, Chang Gyeom KIM, Hong Xian LI, Su Jin PARK, Jong Hyun YOON, Baek Seok LEE, Sun Young LEE
  • Publication number: 20190119709
    Abstract: The present invention relates to a microorganism for producing diamine, in which activity of a protein having an amino acid sequence of SEQ ID NO: 6 or an amino acid sequence having 55% or higher sequence homology with SEQ ID NO: 6 is introduced or enhanced, and a method of producing diamine using the same.
    Type: Application
    Filed: January 4, 2019
    Publication date: April 25, 2019
    Applicant: CJ CHEILJEDANG CORPORATION
    Inventors: Kyoung Min Lee, Su Jin Park, Hee Kyoung Jung, Young Lyeol Yang, Hong Xian Li, Hye Won Um
  • Patent number: 10221434
    Abstract: The present invention relates to a polypeptide which is resistant to feedback inhibition by methionine and has an activity of homoserine O-succinyltransferase, a microorganism for producing O-succinylhomoserine which expresses the polypeptide, and a method for producing O-succinylhomoserine using the same.
    Type: Grant
    Filed: October 22, 2014
    Date of Patent: March 5, 2019
    Assignee: CJ CHEILJEDANG CORPORATION
    Inventors: Chang Il Seo, So Young Kim, Yong Uk Shin, Kwang Ho Na, Hye Won Um, In Kyung Heo
  • Patent number: 10221433
    Abstract: The present invention relates to a recombinant microorganism capable of producing putrescine, in which the microorganism is modified to have enhanced NCgl2522 activity, thereby producing putrescine in a high yield, and a method for producing putrescine using the microorganism.
    Type: Grant
    Filed: February 25, 2014
    Date of Patent: March 5, 2019
    Assignee: CJ CHEILJEDANG CORPORATION
    Inventors: Kyoung Min Lee, Hee Kyoung Jung, Young Lyeol Yang, Hye Won Um, Chang Gyeom Kim, Hong Xian Li, Su Jin Park, Jong Hyun Yoon, Baek Seok Lee, Sun Young Lee
  • Publication number: 20180273992
    Abstract: The present invention relates to a microorganism for producing diamine, in which activity of a protein having an amino acid sequence of SEQ ID NO: 6 or an amino acid sequence having 42% or higher sequence homology with SEQ ID NO: 6 is introduced or enhanced, and a method of producing diamine using the same.
    Type: Application
    Filed: June 5, 2018
    Publication date: September 27, 2018
    Applicant: CJ CHEILJEDANG CORPORATION
    Inventors: Kyoung Min LEE, Su Jin PARK, Hee Kyoung JUNG, Young Lyeol YANG, Hong Xian LI, Hye Won UM
  • Publication number: 20180208909
    Abstract: Disclosed is a modified microorganism producing putrescine or ornithine, and a method for producing putrescine or ornithine using the same.
    Type: Application
    Filed: July 19, 2016
    Publication date: July 26, 2018
    Applicant: CJ Cheijedang Corporation
    Inventors: Su Jin PARK, Young Lyeol YANG, Hye Won UM, Hong Xian LI, Kyoung Min LEE, Baek Seok LEE, Hyo Hyoung LEE, Hee Kyoung JUNG
  • Publication number: 20180187222
    Abstract: The present invention relates to a recombinant microorganism for producing putrescine or ornithine, and a method for producing putrescine or ornithine using the same. Specifically, the present invention relates to a microorganism of the genus Corynebacterium capable of producing putrescine or ornithine, in which an activity of the transcriptional regulator of sugar metabolism (SugR) is weakened, an activity of the citrate synthase (GltA) is enhanced, or both are applied; and a method for producing putrescine or ornithine using the same.
    Type: Application
    Filed: March 29, 2016
    Publication date: July 5, 2018
    Inventors: Hee Kyoung JUNG, Hye Won UM, Hong Xian LI, Su Jin PARK, Young Lyeol YANG, Kyoung Min LEE, Hyo Hyoung LEE
  • Publication number: 20180127351
    Abstract: A method for purifying 1,4-diaminobutane comprising the steps of: separating a second composition including carbonate salt of 1,4-diaminobutane from a first composition including carbonate salt of 1,4-diaminobutane by distillation; and removing carbonate from carbonate salt of 1,4-diaminobutane included in the second composition to recover 1,4-diaminobutane.
    Type: Application
    Filed: May 4, 2016
    Publication date: May 10, 2018
    Inventors: Won Sik GWAK, Hong Xian LI, Hyun Ju WON, Hyo Hyoung LEE, Kyung Su NA, Su Jin PARK, Young Lyeol YANG, Hye Won UM, Chang Yub OH, Kyoung Min LEE
  • Patent number: 9890404
    Abstract: The present invention relates to a putrescine-producing microorganism and a method for producing putrescine using the same. To be more specific, the present invention is directed to a microorganism given the ability to produce putrescine which is generated by blocking a biosynthetic pathway from ornithine to arginine, increasing the intracellular level of glutamate, enhancing the biosynthetic pathway of ornithine from glutamate, and introducing extracellular ornithine decarboxylase; and a method for producing putrescine by using the microorganism.
    Type: Grant
    Filed: December 8, 2011
    Date of Patent: February 13, 2018
    Assignee: CJ CHEILJEDANG CORPORATION
    Inventors: Hyang Choi, Kyoung Min Lee, Min Sun Kang, Sung Hoo Jhon, Hye Won Um, Su Jin Choi, Han Won Lee, Soo An Shin
  • Patent number: 9834491
    Abstract: The present invention relates to a method of producing bio-based homoserine lactone and bio-based organic acid through hydrolysis of O-acyl homoserine produced by a microorganism in the presence of an acid catalyst. According to the present invention, O-acyl homoserine produced by a microorganism is used as a raw material for producing 1,4-butanediol, gamma-butyrolactone, tetrahydrofuran and the like, which are industrially highly useful. The O-acyl homoserine produced by a microorganism can substitute conventional petrochemical products, can solve environmental concerns, including the emission of pollutants and the exhaustion of natural resources, and can be continuously renewable so as not to exhaust natural resources.
    Type: Grant
    Filed: March 19, 2014
    Date of Patent: December 5, 2017
    Assignee: CJ CHEILJEDANG CORPORATION
    Inventors: Han Won Lee, Young Lyeol Yang, So Young Kim, Yong Uk Shin, Jin Sook Chang, Hye Won Um, Young Hyoung Goh, Sung Hoo Jhon
  • Patent number: 9689009
    Abstract: The present invention provides methods for the production of cysteine or derivates thereof by culturing a microorganism having reduced activity of endogenous phosphoserine phosphatase and the activity of PhnC, PhnD, and PhnE is reduced, and enhanced activity of phosphoglycerate dehydrogenase and/or phosphoserine aminotransferase. The O-phosphoserine produced by such an organism can then be reacted with a sulfide in the presence of a sulfydrylase or a microorganism expressing a sulfhydrylase to produce cysteine or a derivative thereof. Microorganisms having these reduced and enhanced properties noted above are also provided herein.
    Type: Grant
    Filed: October 20, 2011
    Date of Patent: June 27, 2017
    Assignee: CJ CHEILJEDANG CORPORATION
    Inventors: Jin Sook Chang, Jae Hyun Jo, Hyun Ae Bae, Byeong Cheol Song, Sol Kim, Hye Won Kim, Hye Won Um, Sung Hoo Jhon, Yong Uk Shin, Eun Bin Yang, Kyoung Min Lee, Soo An Shin
  • Patent number: 9677099
    Abstract: The present invention relates to a recombinant microorganism having enhanced ability of producing putrescine at high yield, which is generated by weakening the activity of NCgl1469 in a microorganism of Corynebacterium genus that is modified to produce putrescine, and a method for producing putrescine using the same.
    Type: Grant
    Filed: January 11, 2013
    Date of Patent: June 13, 2017
    Assignee: CJ Cheiledang Corporation
    Inventors: Su Jin Choi, Hyang Choi, Min Sun Kang, Sung Hoo Jhon, Kyoung Min Lee, Hye Won Um, Young Lyeol Yang
  • Publication number: 20170159085
    Abstract: The present invention relates to a microorganism for producing diamine, in which activity of a protein having an amino acid sequence of SEQ ID NO: 6 or an amine acid sequence having 42% or higher sequence homology with SEQ ID NO: 6 is introduced or enhanced, and a method of producing diamine using the same.
    Type: Application
    Filed: March 27, 2015
    Publication date: June 8, 2017
    Applicant: CJ Cheiljedang Corporation
    Inventors: Kyoung Min LEE, Su Jin PARK, Hee Kyoung JUNG, Young Lyeol YANG, Hong Xian LI, Hye Won UM
  • Patent number: 9657264
    Abstract: The present invention relates to a recombinant microorganism capable of producing putrescine at high yield due to inactivated activity of a protein having an amino acid sequence represented by SEQ ID NO: 2 in the microorganism, and a method of producing putrescine using the microorganism.
    Type: Grant
    Filed: April 24, 2015
    Date of Patent: May 23, 2017
    Assignee: CJ CHEILJEDANG CORPORATION
    Inventors: Kyoung Min Lee, Hongxian Li, Su Jin Park, Young Lyeol Yang, Hye Won Um, Hee Kyoung Jung
  • Patent number: 9593353
    Abstract: The present invention relates to a polypeptide having a resistant to feedback inhibition by methionine and an activity of homoserine O-succinyltransferase, a O-succinyl homoserine-producing microorganism expressing the polypeptide, and a method for producing O-succinyl homoserine using the same.
    Type: Grant
    Filed: October 22, 2014
    Date of Patent: March 14, 2017
    Assignee: CJ CHEILJEDANG CORPORATION
    Inventors: Su Jin Choi, So Young Kim, Chang Il Seo, Yong Uk Shin, Young Lyeol Yang, Hye Won Um, Hye Min Park, Sung Hoo Jhon, Byung Hoon Jung
  • Publication number: 20170044581
    Abstract: The present invention relates to a microorganism for producing diamine, in which activity of a protein having an amino acid sequence of SEQ ID NO: 6 or an amino acid sequence having 55% or higher sequence homology with SEQ ID NO: 6 is introduced or enhanced, and a method of producing diamine using the same.
    Type: Application
    Filed: March 27, 2015
    Publication date: February 16, 2017
    Inventors: Kyoung Min LEE, Su Jin PARK, Hee Kyoung JUNG, Young Lyeol YANG, Hong Xian LI, Hye Won UM
  • Publication number: 20170044487
    Abstract: The present invention relates to a recombinant microorganism capable of producing putrescine at high yield due to inactivated activity of a protein having an amino acid sequence represented by SEQ ID NO: 2 in the microorganism, and a method of producing putrescine using the microorganism.
    Type: Application
    Filed: April 24, 2015
    Publication date: February 16, 2017
    Inventors: Kyoung Min LEE, Hongxian LI, Su Jin PARK, Young Lyeol YANG, Hye Won UM, Hee Kyoung JUNG