Abstract: The present invention relates to a benzamide derivative, a method for preparing same, and a pharmaceutical composition for the prevention or treatment of cancer, containing same as an active ingredient. The benzamide derivative according to an aspect of the present invention can be used in the prevention or treatment of cancer by suppressing EGFR mutation, and, when administered in combination with an EGFR antagonist such as cetuximab, exhibits a significantly synergistic effect on anticancer activity, and thus can be effectively used as an anticancer agent.

Abstract: The present disclosure provides a compound of Chemical Formula (1) or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising the same: wherein X, Z, R1 and R2 are as defined in the specification. The compound of Chemical Formula (1) or pharmaceutically acceptable salt thereof acts as a positive allosteric modulator of metabotropic glutamate receptor subtype 5 (mGluR5), thereby being useful in the prevention or treatment of disorder mediated by glutamate dysfunction and mGluR5.

Abstract: The present disclosure relates to a polypeptide having an acyltransferase activity or a microorganism including the same; a composition for preparing N-acetyl-L-methionine, the composition including the polypeptide or microorganism; and a method of preparing N-acetyl-L-methionine using the polypeptide or microorganism. Further, the present disclosure relates to a polynucleotide encoding the polypeptide and an expression vector including the polynucleotide. Since the microorganism including a novel acyltransferase according to the present disclosure has enhanced acyltransferase activity, this microorganism can be efficiently used for producing N-acetyl-L-methionine by acetylating L-methionine.

Abstract: A capacitance detection circuit using a dynamic current mirror includes a first dynamic current mirror circuit including a reference capacitor connected in series with a first transistor and an input capacitor connected in series with a second transistor, and an oscillator circuit connected to an output node of the first dynamic current mirror circuit and configured to charge an integration capacitance using current output from the first dynamic current mirror circuit. The amount of change in voltage at a first node positioned between a source of the first transistor and the reference capacitor may be identical to the amount of change in voltage at a second node positioned between a source of the second transistor and the input capacitor.

Abstract: An apparatus for measuring a depth of a tread groove may include: a camera module capturing a video including an upper end portion of a tire while rotating around an upper end portion of the tire having a plurality of tread grooves, the video including a plurality of frames; a control module obtaining, based on the plurality of frames, a cross-sectional width of the tire in units of pixels by adding widths and depths of each of the plurality of tread grooves in units of pixels, a width of an inner block in units of pixels, and a width of an outer block in units of pixels, the inner and outer blocks are disposed on the tire; and a conversion module converting the depth of the tread groove in units of pixels into the depth in units of pixels.

Abstract: The present invention provides a method for producing a polyamide with controlled activator addition, and a polyamide produced thereby, the method allowing a polymerization conversion rate and a polydispersity index (PDI) to be enhanced by controlling the addition of an activator so as to prevent a gelation phenomenon that occurs during anionic polymerization.

Abstract: Provided are novel fused-heterocyclyl-carbonohydrazonoyl dicyanide compounds and uses thereof.

Abstract: Provided are novel oxopyridazinyl-phenyl-carbonohydrazonoyl dicyanide compounds and uses thereof.

Abstract: Provided are novel carbonohydrazonoyl dicyanide compounds including two or more aryl or heteroaryl groups connected via a linker and uses thereof.

Abstract: The present invention relates to a method for producing a polyamide by coordinated anionic ring-opening polymerization and a polyamide produced thereby, wherein metal alkoxide as an initiator and metal hydride as a catalyst are added to enable polymerization having a narrow molecular weight distribution and uniform molecular weight within a short polymerization reaction time at a low temperature, without a separate vacuum process, as compared with an existing polymerization method.

Abstract: The present invention relates to novel hydrazone derivatives in which a terminal amine group is substituted with an aryl group or a heteroaryl group, and uses thereof.

Abstract: The present invention relates to a process for preparing a polyamide by anionic polymerization and to a polyamide prepared thereby. A polyamide having an ultra-high molecular weight can be easily prepared by the process for preparing a polyamide according to an embodiment of the present invention. In addition, the polyamide having an ultra-high molecular weight according to an embodiment of the present invention has excellent mechanical properties, particularly, impact resistance.

Abstract: The present invention relates to a lightweight sandwich steel sheet using polyamide, and more particularly, to a lightweight sandwich steel sheet using polyamide and a manufacturing method therefor, the steel sheet being usable at a wider temperature range than that of a conventional sandwich steel sheet and, particularly, having excellent adhesion at a low temperature and remarkably increasing stability and lightweight property.

Abstract: Provided are a method for preparing a polyamide by using a molecular weight controller having a double active group in anionic ring-opening copolymerization of a polyamide, thereby enabling molecular weight to be controlled through the addition reaction of the molecular weight controller, and a polyamide prepared thereby.

Abstract: Provided are a method for producing a polyamide using an end-capping agent and a polyamide produced thereby, wherein the method is an eco-friendly process method without using a solvent as a catalyst and may prepare, by using an end-capping agent for suppressing side reaction, a polymer having a uniform molecular weight and a high conversion rate at a low temperature within a short polymerization time in comparison with a conventional polymerization method.

Abstract: Provided are a method for producing a polyamide including an amide-based molecular weight controller and a polyamide produced thereby, wherein the amide-based molecular weight controller may easily control the molecular weight of the polyamide to have a narrow molecular weight distribution so as to prevent an increase in the molecular weight due to a basic intermediate produced in anionic polymerization and a side reaction generated under a high-temperature polymerization condition.

Abstract: The present invention relates to a lightweight sandwich steel sheet using polyamide, and more particularly, to a lightweight sandwich steel sheet using polyamide and a manufacturing method therefor, the steel sheet being usable at a wider temperature range than that of a conventional sandwich steel sheet and, particularly, having excellent adhesion at a low temperature and remarkably increasing stability and lightweight property.

Abstract: The present invention relates to a method for producing a polyamide by coordinated anionic ring-opening polymerization and a polyamide produced thereby, wherein metal alkoxide as an initiator and metal hydride as a catalyst are added to enable polymerization having a narrow molecular weight distribution and uniform molecular weight within a short polymerization reaction time at a low temperature, without a separate vacuum process, as compared with an existing polymerization method.

Abstract: The present invention provides a method for producing a polyamide with controlled activator addition, and a polyamide produced thereby, the method allowing a polymerization conversion rate and a polydispersity index (PDI) to be enhanced by controlling the addition of an activator so as to prevent a gelation phenomenon that occurs during anionic polymerization.

Abstract: Provided is a method for preparing a polyamide by an anionic polymerization reaction, wherein lactam, and based on 100 parts by weight of the entire lactam, 0.01 parts by weight to 20 parts by weight of an alkali metal as an initiator, 0.3 parts by weight to 10 parts by weight of a molecular weight controller, and 0.002 parts by weight to 1.0 part by weight of carbon dioxide as an activator may be included.