Patents by Inventor Hye-Young Lee

Hye-Young Lee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240141061
    Abstract: The present disclosure relates to an antibody binding specifically to CD55 or an antigen-binding fragment thereof; and a composition for preventing, treating and/or diagnosing cancer containing the same. The antibody of the present disclosure may be used as an effective therapeutic composition for various CD55-mediated diseases since it shows high binding ability and inhibitory effect for the CD55 protein which promotes tumor growth by inhibiting the complement immune mechanism. In addition, the antibody of the present disclosure may be usefully used as an effective therapeutic adjuvant that fundamentally removes drug resistance and remarkably improves therapeutic responsiveness in various diseases in which resistance to therapeutic agents with CDC (complement-dependent cytotoxicity) as a mechanism of action has been induced due to overexpression of CD55.
    Type: Application
    Filed: January 12, 2022
    Publication date: May 2, 2024
    Applicants: SG MEDICAL INC, KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION, KOREA ATOMIC ENERGY RESEARCH INSTITUTE
    Inventors: Ji Chul LEE, Hye In PARK, Sung-Won MIN, Sung-Won MIN, Hyeong Sun KWON, Jae Cheong LIM, So Hee DOH, Eun Ha CHO, So-Young LEE, Sung Hee JUNG
  • Publication number: 20240139362
    Abstract: A sterilization apparatus includes a housing; a sterilization unit for irradiating, with sterilization light, at least one region to be sterilized; and a driving unit for moving the sterilization unit into and out of the housing via an opening of the housing and rotating the sterilization unit about a rotation axis.
    Type: Application
    Filed: January 11, 2024
    Publication date: May 2, 2024
    Inventors: Hyun Woo Choi, Sang Hyoung Lee, Jong Min Lee, Jong Woon Kim, Hae Ryun Lee, Man Young Chun, Hye Jin Park
  • Publication number: 20240142322
    Abstract: A battery pressure measuring sensor according to an embodiment of the present disclosure includes a substrate; a plurality of variable resistor units provided at a plurality of locations in consideration of a swelling characteristic of a battery on the substrate and configured to change a resistance value within a corresponding resistance range according to a pressure applied to each unit; and a plurality of sensing lines configured to be connected to the plurality of variable resistor units, respectively.
    Type: Application
    Filed: November 16, 2022
    Publication date: May 2, 2024
    Applicant: LG Energy Solution, Ltd.
    Inventors: Ki-Young Lee, Dong-Wan Ko, Do-Yul Kim, Hye-Yun Bae
  • Patent number: 11969693
    Abstract: Provided is an ultra large-width coating device applied to a consecutive process. More particularly, the present invention relates to a coating device capable of maximizing productivity by consecutively manufacturing a large-width film without reducing physical properties of the manufactured film by overcoming a problem in that a coating width is limited during a coating process using the existing contact type coating roller, and a method for manufacturing an ultra large-width membrane using the same.
    Type: Grant
    Filed: April 20, 2021
    Date of Patent: April 30, 2024
    Assignees: SK INNOVATION CO., LTD., SK IE TECHNOLOGY CO., LTD.
    Inventors: Dong Jin Joo, Kyu Young Cho, Yun Bong Kim, Su Ji Lee, Won Sub Kwack, Hye Jin Kim
  • Patent number: 11965014
    Abstract: The present invention relates to a novel chimeric antigen receptor comprising a CD99 region which participates in immune synapse stabilization as a backbone of the chimeric antigen receptor, an immune cell comprising the same, and the uses thereof. CD99-based CAR-T cells are capable of forming very stable immune synapses with tumor cells compared to conventional backbone-based CAR-T cells and can exhibit improved tumor therapeutic efficiency, so they can be useful for immune cell therapy for the treatment of cancer.
    Type: Grant
    Filed: July 28, 2021
    Date of Patent: April 23, 2024
    Assignee: TICAROS CO., LTD.
    Inventors: Kyungho Choi, Eun-Young Choi, Giri Nam, Hyung-Bae Park, Ji-Eun Lee, Hye-Ran Yeon
  • Patent number: 11968898
    Abstract: An organic light emitting diode (OLED) includes a first emitting material layer disposed adjacently to a first electrode and a second emitting material layer disposed adjacently to a second electrode. The first emitting material layer includes a first compound having high affinity to holes and a second compound of thermally activated delayed fluorescent material, and the second emitting material layer includes a fourth compound having high affinity to electrons and implementing triplet-triplet annihilation. Two emitting material layers having adjusted energy levels allow the OLED to lower its driving voltages and improve its luminous efficiency and luminous lifetime.
    Type: Grant
    Filed: October 22, 2020
    Date of Patent: April 23, 2024
    Assignee: LG DISPLAY CO., LTD.
    Inventors: Hye-Gun Ryu, Ik-Rang Choe, Jun-Yun Kim, Seong-Keun Kim, Ju-Young Lee
  • Publication number: 20240126074
    Abstract: The present disclosure provides a waveguide display apparatus. The waveguide waveguide display apparatus of the present disclosure is a waveguide display apparatus for correcting curved surface reflection distortion, the waveguide display apparatus including a waveguide for guiding light inputted from the outside; a first diffractive optical element disposed at the waveguide, and diffracting the light inputted from the outside to the inside of the waveguide; and a second diffractive optical element disposed at the waveguide, and diffracting the light guided by the waveguide to output a plurality of diffracted lights in a direction of a curved surface reflector located outside, wherein the second diffractive optical element has a structure of a diffraction grating corresponding to a curvature of the curved surface reflector such that the diffracted lights are reflected at different locations of the curved surface reflector in directions parallel to each other.
    Type: Application
    Filed: September 30, 2022
    Publication date: April 18, 2024
    Applicant: LG Chem, Ltd.
    Inventors: Jae Jin Kim, Bo Ra Jung, Hye Won Hwang, Yeon Jae Yoo, Joon Young Lee, Bu Gon Shin, Min Soo Song
  • Publication number: 20240113318
    Abstract: A polymer electrolyte membrane having improved chemical or mechanical durability is provided. The present disclosure relates to a polymer electrolyte membrane, and the polymer electrolyte membrane according to the present disclosure comprises a porous support and a composite layer containing a first ionomer filled in the porous support, wherein the polymer electrolyte membrane comprises a first segment having a first durability and a second segment having a second durability, and the first durability is higher than the second durability.
    Type: Application
    Filed: September 17, 2021
    Publication date: April 4, 2024
    Inventors: Eun Su LEE, Dong Hoon LEE, Na Young KIM, Jung Hwa PARK, Hye Song LEE
  • Patent number: 11939334
    Abstract: The present disclosure relates to a novel PLK1 degradation inducing compound having a structure according to Formula I, a method for preparing the same, and the use thereof. The compounds of the present disclosure exhibit an effect of inducing PLK1 degradation. Therefore, the compounds of the present disclosure may be effectively utilized for preventing or treating PLK1-related diseases.
    Type: Grant
    Filed: August 10, 2022
    Date of Patent: March 26, 2024
    Assignee: UPPTHERA, INC.
    Inventors: Soo Hee Ryu, Im Suk Min, Han Kyu Lee, Seong Hoon Kim, Hye Guk Ryu, Keum Young Kang, Sang Youn Kim, So Hyun Chung, Jun Kyu Lee, Gibbeum Lee
  • Patent number: 11943998
    Abstract: The present disclosure provides an organic light emitting diode including a first electrode; a second electrode facing the first electrode; and an emitting material layer including a first compound and a second compound positioned between the first and second electrodes, wherein the first compound includes a hexagonal-ring moiety including one boron atom, one oxygen atom and four carbon atoms, and the second compound includes a hexagonal-ring moiety including one boron atom, one nitrogen atom and four carbon atoms, and an organic light emitting device including the organic light emitting diode.
    Type: Grant
    Filed: November 20, 2020
    Date of Patent: March 26, 2024
    Assignee: LG DISPLAY CO., LTD.
    Inventors: Ik-Rang Choe, Hye-Gun Ryu, Jun-Yun Kim, Seong-Keun Kim, Ju-Young Lee
  • Patent number: 11935701
    Abstract: A capacitor component includes a body including dielectric layers, first and second internal electrodes, laminated in a first direction, facing each other, and first and second cover portions, disposed on outermost portions of the first and second internal electrodes, and first and second external electrodes, respectively disposed on both external surfaces of the body in a second direction, perpendicular to the first direction, and respectively connected to the first and second internal electrodes. An indentation including a glass is disposed at at least one of boundaries between the first internal electrodes and the first external electrode or one of boundaries between the second internal electrodes and the second external electrode.
    Type: Grant
    Filed: April 4, 2023
    Date of Patent: March 19, 2024
    Assignee: SAMSUNG ELECTRO-MECHANICS CO., LTD.
    Inventors: Jang Yeol Lee, Ji Hong Jo, Yoo Jeong Lee, Myung Jun Park, Jong Ho Lee, Hye Young Choi, Jae Hyun Lee, Hyun Hee Gu
  • Patent number: 11922860
    Abstract: Provided is a pixel driving circuit including a first circuit configured to control, in a data writing mode, a signal related to driving of one or more light-emitting elements, and a second circuit configured to supply, in a driving mode, power to the one or more light-emitting elements based on a signal transmitted from the first circuit.
    Type: Grant
    Filed: September 16, 2022
    Date of Patent: March 5, 2024
    Assignee: Sapien Semiconductors Inc.
    Inventors: Sung Ho Hwang, Ji Han Kim, Ji Haeng Lee, Hye Min Bae, Dae Young Jung
  • Publication number: 20240074296
    Abstract: A display panel includes a first substrate including a display area, in which a plurality of pixel areas is arranged, and a non-display area around the display area, a second substrate disposed opposite to the first substrate, a light emitting array disposed on the first substrate and including a plurality of light emitting elements corresponding to the plurality of pixel areas, a sealing layer disposed in the non-display area between the first substrate and the second substrate and bonding the first substrate and the second substrate to each other, a vacuum layer sealed by the sealing layer and defined between the light emitting array and the second substrate, and a reflection adjustment layer disposed on the second substrate and absorbing a portion of external light, where the reflection adjustment layer includes a plurality of protrusions protruding toward the light emitting array and exposed to the vacuum layer.
    Type: Application
    Filed: April 12, 2023
    Publication date: February 29, 2024
    Inventors: Jong Ho SON, Dae Won KIM, Hye Beom SHIN, Jin Hyeong LEE, Sun Young CHANG
  • Patent number: 11912710
    Abstract: The present disclosure relates to a novel PLK1 degradation inducing compound having a structure according to Formula I, a method for preparing the same, and the use thereof. The compounds of the present disclosure exhibit an effect of inducing PLK1 degradation. Therefore, the compounds of the present disclosure may be effectively utilized for preventing or treating PLK1-related diseases.
    Type: Grant
    Filed: August 10, 2022
    Date of Patent: February 27, 2024
    Assignee: UPPTHERA, INC.
    Inventors: Soo Hee Ryu, Im Suk Min, Han Kyu Lee, Seong Hoon Kim, Hye Guk Ryu, Keum Young Kang, Sang Youn Kim, So Hyun Chung, Jun Kyu Lee, Gibbeum Lee
  • Publication number: 20200405884
    Abstract: Described herein are compositions and methods for treating diseases and disorders of the brain using a non-viral nanoparticle delivery of CRISPR. Disclosed herein are compositions comprising CRISPR-Gold compositions comprising DNA oligonucleotides, RNA-directed nucleases and guide RNAs. The methods include modulating expression of a gene in a cell using said compositions, inducing site-specific DNA cleavage in a cell, and treating a subject having fragile X syndrome caused by increased metabotropic glutamate receptor 5 signaling using the compositions disclosed herein.
    Type: Application
    Filed: March 8, 2019
    Publication date: December 31, 2020
    Inventors: Hye Young Lee, Bumwhee Lee, Kunwoo Lee, Hyo Min Park
  • Publication number: 20200131579
    Abstract: The present disclosure relates to an improved method for providing information on breast cancer and a diagnostic kit therefore, and more specifically, to an improved kit for diagnosing breast cancer by using a one-tube nested PCR and a diagnostic method therefor.
    Type: Application
    Filed: February 28, 2014
    Publication date: April 30, 2020
    Inventors: Hye Young LEE, Hye Young WANG, Yeun KIM
  • Patent number: 10072302
    Abstract: There are provided an improved cervical cancer diagnosing method and a diagnostic kit for same. According to the present invention, it is possible to more rapidly and accurately provide a patient group requiring a clinical treatment and a prevention treatment in terms of a technical aspect to predict that the limitation of the existing HPV DNA test method can be overcome, automate the RNA extraction from eliminated cells, and more rapidly provide more objective and accurate results because the result analysis can be performed by software by using the real-time RT-PCR.
    Type: Grant
    Filed: December 5, 2013
    Date of Patent: September 11, 2018
    Assignees: OPTIPHARM.CO., LTD., UNIVERSITY INDUSTRY FOUNDATION, YONSEI UNIVERSITY WONJU CAMPUS
    Inventors: Hye Young Lee, Hye Young Wang
  • Publication number: 20170211156
    Abstract: There are provided an information offering method for diagnosing breast cancer comprising: (a) separating total RNA from a cell obtained from a tissue or blood of a suspected cancer patient; (b) synthesizing a cDNA from the separated total RNA; (c) performing a real-time PCR with the synthesized cDNA by using primer pair mix and probe mix that can amplify human epidermal growth factor receptor 2 (HER2); wherein, the primer pair mix that can amplify human epidermal growth factor receptor 2 (HER2) are described as SEQ ID Nos.:1 and 2, 3 and 4, and 6 and 7 and the probe mix are described as SEQ ID Nos.: 5, 8, and 9.
    Type: Application
    Filed: March 9, 2017
    Publication date: July 27, 2017
    Applicants: Optipharm Co., Ltd., University Industry Foundation, Yonsei University Wonju Campus
    Inventors: Hye Young Lee, Seung Il Kim, Hye Young Wang, Sang Jung Park
  • Publication number: 20160376662
    Abstract: There are provided an improved cervical cancer diagnosing method and a diagnostic kit for same. According to the present invention, it is possible to more rapidly and accurately provide a patient group requiring a clinical treatment and a prevention treatment in terms of a technical aspect to predict that the limitation of the existing HPV DNA test method can be overcome, automate the RNA extraction from eliminated cells, and more rapidly provide more objective and accurate results because the result analysis can be performed by software by using the real-time RT-PCR.
    Type: Application
    Filed: December 5, 2013
    Publication date: December 29, 2016
    Inventors: Hye Young LEE, Hye Young WANG, Yeun KIM
  • Publication number: 20160348181
    Abstract: There are provided a method for an early diagnosis and a screening test for a therapeutic agent of breast cancer by using tissue and blood, and a quantitative reverse transcription polymerase chain reaction kit for same. According to the present invention, it is possible to provide help in more effective treatment and diagnosis of breast cancer through expression rates of HER2 expressed in blood and a cancer-related marker in the blood in addition to a tissue specimen.
    Type: Application
    Filed: December 20, 2013
    Publication date: December 1, 2016
    Inventors: Hye Young LEE, Hye Young WANG, Yeun KIM