Patents by Inventor Hyeon-Je Cho
Hyeon-Je Cho has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11965168Abstract: Soybean plants producing soybean seeds comprising leghemoglobin are produced by modifying the genome of the soybean plant. Soybean plants, soybean seeds and soy protein compositions comprising leghemoglobin are provided. Soybean plants, soybean seeds and soy protein compositions comprising leghemoglobin and additionally one or more of high oleic acid, low linolenic acid, high protein, low stachyose, low raffinose and low protease inhibitors are provided. Protein compositions comprising leghemoglobin, such as soy isolates and concentrates can be made from the soybean seeds. Additionally, methods for generating and using plants, seeds and protein compositions comprising leghemoglobin are disclosed.Type: GrantFiled: June 30, 2022Date of Patent: April 23, 2024Assignee: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: Hyeon-Je Cho, John D Everard, Anthony J Kinney, Zhan-Bin Liu, Knut Meyer, Thomas G Patterson, Kevin G Ripp, Bo Shen
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Publication number: 20230380373Abstract: Soybean plants producing soybean seeds comprising leghemoglobin are produced by modifying the genome of the soybean plant. Soybean plants, soybean seeds and soy protein compositions comprising leghemoglobin are provided. Soybean plants, soybean seeds and soy protein compositions comprising leghemoglobin and additionally one or more of high oleic acid, low linolenic acid, high protein, low stachyose, low raffinose and low protease inhibitors are provided. Protein compositions comprising leghemoglobin, such as soy isolates and concentrates can be made from the soybean seeds. Additionally, methods for generating and using plants, seeds and protein compositions comprising leghemoglobin are disclosed.Type: ApplicationFiled: October 22, 2021Publication date: November 30, 2023Applicant: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: HYEON-JE CHO, JOHN D. EVERARD, ANTHONY KINNEY, ZHAN-BIN LIU, KNUT MEYER, THOMAS G. PATTERSON, KEVIN G. RIPP, BO SHEN
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Publication number: 20230091338Abstract: Compositions and methods are provided for an inducible, high efficiency intra-genomic homologous recombination (IGHR) system in plants, that can be used for non-chimeric, heritable gene targeting. The advantage of IGHR approach to targeted integration is that every cell contains donor DNA and nuclease-encoding sequences, so that there are many potentially homology-directed targeting events that can occur during plant development.Type: ApplicationFiled: February 22, 2021Publication date: March 23, 2023Applicant: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: AJITH ANAND, MAREN L ARLING, PIERLUIGI BARONE, HYEON-JE CHO, WILLIAM JAMES GORDON-KAMM, SANDEEP KUMAR, BRIAN LENDERTS, KEITH S LOWE, SERGEI SVITASHEV, XINLI EMILY WU
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Publication number: 20220340923Abstract: Soybean plants producing soybean seeds comprising leghemoglobin are produced by modifying the genome of the soybean plant. Soybean plants, soybean seeds and soy protein compositions comprising leghemoglobin are provided. Soybean plants, soybean seeds and soy protein compositions comprising leghemoglobin and additionally one or more of high oleic acid, low linolenic acid, high protein, low stachyose, low raffinose and low protease inhibitors are provided. Protein compositions comprising leghemoglobin, such as soy isolates and concentrates can be made from the soybean seeds. Additionally, methods for generating and using plants, seeds and protein compositions comprising leghemoglobin are disclosed.Type: ApplicationFiled: June 30, 2022Publication date: October 27, 2022Applicant: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: HYEON-JE CHO, JOHN D EVERARD, ANTHONY J. KINNEY, ZHAN-BIN LIU, KNUT MEYER, THOMAS G PATTERSON, KEVIN G RIPP, BO SHEN
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Patent number: 11359206Abstract: Soybean plants producing soybean seeds comprising leghemoglobin are produced by modifying the genome of the soybean plant. Soybean plants, soybean seeds and soy protein compositions comprising leghemoglobin are provided. Soybean plants, soybean seeds and soy protein compositions comprising leghemoglobin and additionally one or more of high oleic acid, low linolenic acid, high protein, low stachyose, low raffinose and low protease inhibitors are provided. Protein compositions comprising leghemoglobin, such as soy isolates and concentrates can be made from the soybean seeds. Additionally, methods for generating and using plants, seeds and protein compositions comprising leghemoglobin are disclosed.Type: GrantFiled: December 21, 2021Date of Patent: June 14, 2022Inventors: Hyeon-Je Cho, John D Everard, Anthony J Kinney, Zhan-Bin Liu, Knut Meyer, Thomas G Patterson, Kevin G Ripp, Bo Shen
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Publication number: 20220127632Abstract: Soybean plants producing soybean seeds comprising leghemoglobin are produced by modifying the genome of the soybean plant. Soybean plants, soybean seeds and soy protein compositions comprising leghemoglobin are provided. Soybean plants, soybean seeds and soy protein compositions comprising leghemoglobin and additionally one or more of high oleic acid, low linolenic acid, high protein, low stachyose, low raffinose and low protease inhibitors are provided. Protein compositions comprising leghemoglobin, such as soy isolates and concentrates can be made from the soybean seeds. Additionally, methods for generating and using plants, seeds and protein compositions comprising leghemoglobin are disclosed.Type: ApplicationFiled: December 21, 2021Publication date: April 28, 2022Applicant: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: HYEON-JE CHO, JOHN D EVERARD, ANTHONY J KINNEY, ZHAN-BIN LIU, KNUT MEYER, THOMAS G PATTERSON, KEVIN G RIPP, BO SHEN
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Publication number: 20220127631Abstract: Soybean plants producing soybean seeds comprising leghemoglobin are produced by modifying the genome of the soybean plant. Soybean plants, soybean seeds and soy protein compositions comprising leghemoglobin are provided. Soybean plants, soybean seeds and soy protein compositions comprising leghemoglobin and additionally one or more of high oleic acid, low linolenic acid, high protein, low stachyose, low raffinose and low protease inhibitors are provided. Protein compositions comprising leghemoglobin, such as soy isolates and concentrates can be made from the soybean seeds. Additionally, methods for generating and using plants, seeds and protein compositions comprising leghemoglobin are disclosed.Type: ApplicationFiled: October 22, 2021Publication date: April 28, 2022Applicant: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: HYEON-JE CHO, JOHN D EVERARD, ANTHONY J KINNEY, ZHAN-BIN LIU, KNUT MEYER, THOMAS G PATTERSON, KEVIN G RIPP, BO SHEN
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Patent number: 11236347Abstract: Methods and compositions for Ochrobactrum-mediated transformation of plants are provided. Methods include but are not limited to using an Ochrobactrum strain to transfer a polynucleotide of interest to a plant cell. These include VirD2-dependent methods. Compositions include an Ochrobactrum strain, transfer DNAs, constructs and/or plasmids. These include Ochrobactrum strains having a plasmid comprising one or more virulence gene(s), border region, and/or origin of replication. Plant cells, tissues, plants, and seeds comprising a polynucleotide of interest produced by the methods are also provided.Type: GrantFiled: August 26, 2016Date of Patent: February 1, 2022Inventors: Ajith Anand, Steven Henry Bass, Sean M. Bertain, Hyeon-Je Cho, Anthony J. Kinney, Theodore M. Klein, Michael Lassner, Kevin E. McBride, York Moy, Barbara Ann Marie Rosen, Jun-Zhi Wei
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Publication number: 20210395760Abstract: Methods and compositions for increasing, improving or enhancing gene editing efficiency are provided. Configurations of Ochrobactrum and Agrobacterium based vector components such as CRISPR Cas endonucleases and guide RNAs are provided that improve efficiency of targeted genome modification.Type: ApplicationFiled: October 30, 2019Publication date: December 23, 2021Applicant: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: JYOTHI BOLAR, SHUJUN CHANG, HYEON-JE CHO, ZHAN-BIN LIU
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Publication number: 20210395758Abstract: Modified Ochrobactrum strains, methods of producing such modified Ochrobactrum strains, and methods of using such modified Ochrobactrum strains for producing transformed plants are disclosed herein.Type: ApplicationFiled: October 30, 2019Publication date: December 23, 2021Applicant: PIONEER HI-BRED INTERNATIONAL, INC.Inventor: HYEON-JE CHO
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Publication number: 20210277409Abstract: Spectinomycin resistant or streptomycin resistant transgenic plants and methods of making such plants are provided.Type: ApplicationFiled: June 25, 2019Publication date: September 9, 2021Applicant: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: AJITH ANAND, HYEON-JE CHO, THEODORE M KLEIN
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Publication number: 20210054389Abstract: Compositions and methods are provided for the efficient transformation of a dicot plant. More particularly, compositions and methods of the present disclosure find use in agriculture for bacteria-mediated and biolistic-mediated transformation of a dicotyledonous plant. The compositions include cultivation media comprising methionine and glutamine supplemented with auxins for use in methods directed to bacteria-mediated and biolistic-mediated transformation of a dicot plant with a gene of interest.Type: ApplicationFiled: December 19, 2018Publication date: February 25, 2021Applicant: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: HYEON-JE CHO, TAI MINH
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Publication number: 20210002657Abstract: Methods of detecting the impacts on plant health attributable to the presence of one or more agronomically important polypeptides of interest in a transgenic plant are disclosed. The methods involve transforming plants or plant cells with nucleic acid sequences encoding proteins of agronomically important traits. The transformed plants or plant cells expressing the nucleic acid sequences encoding the proteins of agronomically important traits are compared to transformed plants or plant cells expressing a neutral control gene to detect the impacts on plant health attributable to the presence of the one or more agronomically important polypeptides of interest.Type: ApplicationFiled: February 28, 2019Publication date: January 7, 2021Applicant: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: STEVEN HENRY BASS, HYEON-JE CHO, MYEONG-JE CHO, VIRGINIA CRANE, MATTHEW J HECKERT, JIAN JIN, TODD J JONES, KEVIN E MCBRIDE, JEANNE SANDAHL, SHIV BAHADUR TIWARI
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Publication number: 20190078106Abstract: The present disclosure provides methods and compositions for the vectors comprising vir genes. The present disclosure further provides a vector comprising: (a) an origin of replication for propagation and stable maintenance in Escherichia coli; (b) an origin of replication for propagation and stable maintenance in Agrobacterium spp.; (c) a selectable marker gene; and (d) Rhizobiaceae virulence genes virB1-B11 or r-virB1-B11, virC1-C2 or r-virC1-C2, virD1-D2 or r-virD1-D2, and virG or r-virG, or variants and derivatives thereof, wherein the vector comprising the virulence genes r-virB1-B11, r-virC1-C2, r-virD1-D2, and r-virG further comprises a r-galls virulence gene, or variants and derivatives thereof. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.Type: ApplicationFiled: August 26, 2016Publication date: March 14, 2019Applicant: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: AJITH ANAND, STEVEN HENRY BASS, HYEON-JE CHO, THEODORE MITCHELL KLEIN, MICHAEL LASSNER, KEVIN E. MCBRIDE
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Publication number: 20180216123Abstract: Methods and compositions for Ochrobactrum-mediated transformation of plants are provided. Methods include but are not limited to using an Ochrobactrum strain to transfer a polynucleotide of interest to a plant cell. These include VirD2-dependent methods. Compositions include an Ochrobactrum strain, transfer DNAs, constructs and/or plasmids. These include Ochrobactrum strains having a plasmid comprising one or more virulence gene(s), border region, and/or origin of replication. Plant cells, tissues, plants, and seeds comprising a polynucleotide of interest produced by the methods are also provided.Type: ApplicationFiled: August 26, 2016Publication date: August 2, 2018Applicants: PIONEER HI-BRED INTERNATIONAL, INC., E. I. DU PONT DE NEMOURS AND COMPANYInventors: AJITH ANAND, STEVEN HENRY BASS, SEAN M. BERTAIN, HYEON-JE CHO, ANTHONY J. KINNEY, THEODORE M. KLEIN, MICHAEL LASSNER, KEVIN E. MCBRIDE, YORK MOY, BARBARA ANN MARIE ROSEN, JUN-ZHI WEI
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Patent number: 8962328Abstract: Compositions and methods are provided for the efficient transformation of a dicot plant. More particularly, compositions and methods of the present invention find use in agriculture for Agrobacterium-mediated transformation of a dicotyledonous plant. The compositions include cultivation media comprising high concentrations of sucrose and glucose. The cultivation media find use in methods directed to Agrobacterium-mediated transformation of a dicot plant with a gene of interest. In this manner, any gene of interest can be introduced into a dicot plant with high transformation efficiency and reduced tissue necrosis.Type: GrantFiled: April 3, 2012Date of Patent: February 24, 2015Assignees: Pioneer Bred International Inc, E.I. DuPont de NemoursInventors: Hyeon-Je Cho, Linda A. Castle, Theodore M. Klein, Tai Minh, York Moy
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Patent number: 8732832Abstract: Routing apparatus and method for detecting a server attack are disclosed. The routing apparatus includes: a reception unit configured to receive a packet transmitted in a network; a transmission unit configured to transmit the packet along a transmission path; a memory unit configured to store data and/or information required for an operation; and a controller configured to set the transmission path of the packet in the network and perform packet switching along the set transmission path, wherein the reception unit receives server state information from servers at every certain time, the memory unit stores the received server state information, and the controller calculates a change in the state of the servers based on the received server state information, and determines that a server is attacked when a change in the state of the server is greater than a certain threshold value.Type: GrantFiled: December 2, 2011Date of Patent: May 20, 2014Assignee: Electronics and Telecommunications Research InstituteInventors: Hak Suh Kim, Kyoung Soon Kang, Gang Uk Hwang, Hyeon Je Cho, Myung Woo Lee
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Publication number: 20120255070Abstract: Compositions and methods are provided for the efficient transformation of a dicot plant. More particularly, compositions and methods of the present invention find use in agriculture for Agrobacterium-mediated transformation of a dicotyledonous plant. The compositions include cultivation media comprising high concentrations of sucrose and glucose. The cultivation media find use in methods directed to Agrobacterium-mediated transformation of a dicot plant with a gene of interest. In this manner, any gene of interest can be introduced into a dicot plant with high transformation efficiency and reduced tissue necrosis.Type: ApplicationFiled: April 3, 2012Publication date: October 4, 2012Applicant: Pioneer Hi Bred International Inc.Inventors: Hyeon-Je Cho, Linda A. Castle, Theodore M. Klein, Tai Minh, York Moy
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Publication number: 20120144487Abstract: Routing apparatus and method for detecting a server attack are disclosed. The routing apparatus includes: a reception unit configured to receive a packet transmitted in a network; a transmission unit configured to transmit the packet along a transmission path; a memory unit configured to store data and/or information required for an operation; and a controller configured to set the transmission path of the packet in the network and perform packet switching along the set transmission path, wherein the reception unit receives server state information from servers at every certain time, the memory unit stores the received server state information, and the controller calculates a change in the state of the servers based on the received server state information, and determines that a server is attacked when a change in the state of the server is greater than a certain threshold value.Type: ApplicationFiled: December 2, 2011Publication date: June 7, 2012Applicant: Electronics and Telecommunications Research InstituteInventors: Hak Suh KIM, Kyoung Soon KANG, Gang Uk HWANG, Hyeon Je CHO, Myung Woo LEE
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Publication number: 20080234130Abstract: Methods and compositions are provided related to improved plants that are tolerant to more than one herbicide. Particularly, the invention provides plants that are tolerant of glyphosate and are tolerant to at least one ALS inhibitor, and methods of use thereof. The glyphosate/ALS inhibitor-tolerant plants comprise a polynucleotide that encodes a polypeptide that confers tolerance to glyphosate and a polynucleotide that encodes an ALS inhibitor-tolerant polypeptide. In specific embodiments, a plant of the invention expresses a GAT polypeptide and an HRA polypeptide. Methods to control weeds, improve plant yield, and increase transformation efficiencies are provided.Type: ApplicationFiled: August 22, 2006Publication date: September 25, 2008Applicants: Pioneer Hi-Bred International, Inc., E.I. du Pont de Nemours and CompanyInventors: Billy Fred McCutchen, Linda A. Castle, Timothy K. Chicoine, Hyeon-Je Cho, Jon S. Claus, Jerry M. Green, Anthony D. Guida, Christine B. Hazel, Matthew J. Heckert, Jeffrey M. Hegstad, James M. Hutchison, Donglong Liu, Albert L. Lu, Wayne J. Mehre, York Moy, Paul D. Olson, Kenneth A. Peeples, David W. Saunders, Mark D. Vogt, Jack Q. Wilkinson, James F. H. Wong