Abstract: The present invention relates to a novel benzopyran derivative useful for preparing a drug for treating cancer, and more specifically, to a novel benzopyran derivative which is a micromolecule having a macrophage inhibitory effect and is useful for preparing a drug for cancer treatment. The drug particularly inhibits the differentiation of immune macrophages to stimulate the immune system, and thus is useful for treating immune-related cancers.

Abstract: Disclosed herein is an actuator for driving zoom lenses, where the zoom actuator comprises a first carrier having attached thereto a first lens and movable along an optical axis; a second carrier having attached thereto a second lens and being capable of moving along the optical axis and running anterior or posterior to the first carrier; a housing enclosing the first and second carriers; a first magnet attached to the first carrier; a second magnet attached to the second carrier; a first coil unit mounted to the housing and facing the first magnet; a second coil unit mounted to the housing and facing the second magnet; and a plurality of balls; with at least one of said plurality of balls positioned between the housing and the first carrier; and at least one of said plurality of balls positioned between the housing and the second carrier.

Abstract: Security check methods and systems over a user on a vehicle may be provided. The security check method including checking an allowed security right to a destination of a vehicle for entry, detecting a security right of a user on the vehicle, and performing a security process related to getting off the vehicle, based on the security right of the user and the allowed security right may be provided.

Abstract: There is provided a binder, which binds to CD47 overexpressed in cancer cells and has an improved binding affinity for CD47, and a liposome complex. There is also provided a binder, which binds to CD47 overexpressed in cancer cells and includes an amino acid sequence represented by SEQ ID NO: 1 or SEQ ID NO: 2, and a binder-conjugated liposome complex, in which the binder is conjugated to a liposome.

Abstract: There is provided a polynucleotide for cancer treatment, which is a novel polynucleotide for cancer treatment, is used in the form being captured in liposomal nanoparticles that form a complex with a binder that binds to CD47 and has a mechanism to kill cancer cells by maximizing the metabolic vulnerability of cancer cells. There is also provided a polynucleotide for cancer treatment, encoding an amino acid sequence represented by SEQ ID NO: 3.

Abstract: There is provided a liposome complex for cancer treatment including a novel CD47 binder and a polynucleotide, in which the liposome complex has a mechanism to kill cancer cells by maximizing the metabolic vulnerability of cancer cells. There is also provided a complex for cancer treatment, which includes a polynucleotide encoding an amino acid sequence represented by SEQ ID NO: 3, a liposome in which the polynucleotide is captured, and a binder which is conjugated to the liposome, binds to CD47 overexpressed in cancer cells, and includes an amino acid sequence represented by SEQ ID NO: 1 or SEQ ID NO: 2.

Abstract: Security check methods and systems over a user on a vehicle may be provided. The security check method including checking an allowed security right to a destination of a vehicle for entry, detecting a security right of a user on the vehicle, and performing a security process related to getting off the vehicle, based on the security right of the user and the allowed security right may be provided.

Abstract: Disclosed is a method for producing soluble CRM197 protein at high yield by overexpressing the protein in the cytoplasm of E. coli. The method includes a step of culturing recombinant E. coli harboring an expression plasmid carrying a gene sequence coding for a recombinant CRM197 protein under a condition suitable for expression of the recombinant CRM197 protein which has a histidine-tag attached to the C-terminus of CRM197 and a maltose-binding protein (MBP) attached to the N-terminus of CRM197. The method further includes a step of purifying after the culturing, wherein the step of purifying comprises a step of treating with tobacco etch virus (TEV) protease to remove the maltose-binding protein and a step of removing the histidine-tag via histidine-tag affinity chromatography.

Abstract: The present invention relates to a passive microwave sounder for a satellite, having a fixed reflection plate.

Abstract: Disclosed is a method for expressing and purifying insoluble proteins of CRM197. The method includes: culturing a transformant transformed with an expression vector containing a gene encoding CRM197 protein; obtaining a culture of the transformant and disrupting the cell to recover an inclusion body; solubilizing the inclusion body; treating the solubilized inclusion body with a refolding reaction mixture and performing a refolding process; and purifying the refolded CRM197 protein by chromatography.

Abstract: Disclosed is a method for producing soluble CRM197 protein at high yield by overexpressing the protein in the cytoplasm of E. coli. The method includes a step of culturing recombinant E. coli harboring an expression plasmid carrying a gene sequence coding for a recombinant CRM197 protein under a condition suitable for expression of the recombinant CRM197 protein which has a histidine-tag attached to the C-terminus of CRM197 and a maltose-binding protein (MBP) attached to the N-terminus of CRM197. The method further includes a step of purifying after the culturing, wherein the step of purifying comprises a step of treating with tobacco etch virus (TEV) protease to remove the maltose-binding protein and a step of removing the histidine-tag via histidine-tag affinity chromatography.

Abstract: The present invention relates to a passive microwave sounder for a satellite, having a fixed reflection plate.

Abstract: Disclosed is a method for four-path tree structured vector quantization, comprising: (a) placing codebook vectors where magnitudes of vectors are arranged in order at lowermost nodes; (b) configuring upper nodes by averaging vector values of the lowermost adjacent four nodes; (c) calculating mean square errors to paths of the upper nodes (A, B, C, and D) corresponding to four paths from an input vector ‘X’; (d) presetting a threshold between 0 and 1 after the ‘(c)’; (e) calculating thresholds between the input vector ‘X’ and four paths ‘A’, ‘B’, ‘C’, and ‘D’, based on the mean square errors; and (f) comparing the thresholds calculated in the ‘(d)’ with the preset threshold to select a path having a threshold greater than the preset threshold, in which dynamic four-path tree structured vector quantization is used instead of conventional dynamic two-path tree structured vector quantization, thereby more efficiently and quickly searching a codebook.

Abstract: Disclosed is a method for four-path tree structured vector quantization, comprising: (a) placing codebook vectors where magnitudes of vectors are arranged in order at lowermost nodes; (b) configuring upper nodes by averaging vector values of the lowermost adjacent four nodes; (c) calculating mean square errors to paths of the upper nodes (A, B, C, and D) corresponding to four paths from an input vector ‘X’; (d) presetting a threshold between 0 and 1 after the ‘(c)’; (e) calculating thresholds between the input vector ‘X’ and four paths ‘A’, ‘B’, ‘C’, and ‘D’, based on the mean square errors; and (f) comparing the thresholds calculated in the ‘(d)’ with the preset threshold to select a path having a threshold greater than the preset threshold, in which dynamic four-path tree structured vector quantization is used instead of conventional dynamic two-path tree structured vector quantization, thereby more efficiently and quickly searching a codebook.

Abstract: Disclosed herein are a system for automatically landing an aircraft using image signals and a method of controlling the system. The system includes an altimeter installed on the aircraft; a landing mark placed at a landing location on a landing runway; a camera installed on the aircraft, oriented toward the front of the aircraft, and configured to detect the shape of the landing mark in image information form; and a FCC configured to calculate the angle between the aircraft and the ground, the ground range and the slant range between the aircraft and the landing location using the altitude information measured by the altimeter, the image information of the landing mark captured by the camera, angle information composed of the pitch, roll and yaw angles of the aircraft, and the angle of entry into the landing runway, and configured to control the automatic landing of the aircraft.

Abstract: Provided is an altitude measurement apparatus and method that may measure an altitude of an aircraft without using a separate altimeter. The altitude measurement apparatus may include a camera unit being provided to a vertical takeoff and landing (VTOL) aircraft to collect an image of a circular mark formed on the ground, and a calculation unit to calculate an altitude of the VTOL aircraft based on the collected image. Accordingly, the altitude measurement apparatus may measure the altitude using a simple structure such as the circular mark formed on the ground, and be configured at inexpensive costs.

Abstract: Disclosed herein are a system for automatically landing an aircraft using image signals and a method of controlling the system. The system includes an altimeter installed on the aircraft; a landing mark placed at a landing location on a landing runway; a camera installed on the aircraft, oriented toward the front of the aircraft, and configured to detect the shape of the landing mark in image information form; and a FCC configured to calculate the angle between the aircraft and the ground, the ground range and the slant range between the aircraft and the landing location using the altitude information measured by the altimeter, the image information of the landing mark captured by the camera, angle information composed of the pitch, roll and yaw angles of the aircraft, and the angle of entry into the landing runway, and configured to control the automatic landing of the aircraft.

Abstract: Provided is an altitude measurement apparatus and method that may measure an altitude of an aircraft without using a separate altimeter. The altitude measurement apparatus may include a camera unit being provided to a vertical takeoff and landing (VTOL) aircraft to collect an image of a circular mark formed on the ground, and a calculation unit to calculate an altitude of the VTOL aircraft based on the collected image. Accordingly, the altitude measurement apparatus may measure the altitude using a simple structure such as the circular mark formed on the ground, and be configured at inexpensive costs.

Abstract: Disclosed herein are a system for automatically landing an aircraft using image signals and a method of controlling the system. The system includes an altimeter installed on the aircraft; a landing mark placed at a landing location on a landing runway; a camera installed on the aircraft, oriented toward the front of the aircraft, and configured to detect the shape of the landing mark in image information form; and a FCC configured to calculate the angle between the aircraft and the ground, the ground range and the slant range between the aircraft and the landing location using the altitude information measured by the altimeter, the image information of the landing mark captured by the camera, angle information composed of the pitch, roll and yaw angles of the aircraft, and the angle of entry into the landing runway, and configured to control the automatic landing of the aircraft.

Abstract: Disclosed herein are a system for automatically landing an aircraft using image signals and a method of controlling the system. The system includes an altimeter installed on the aircraft; a landing mark placed at a landing location on a landing runway; a camera installed on the aircraft, oriented toward the front of the aircraft, and configured to detect the shape of the landing mark in image information form; and a FCC configured to calculate the angle between the aircraft and the ground, the ground range and the slant range between the aircraft and the landing location using the altitude information measured by the altimeter, the image information of the landing mark captured by the camera, angle information composed of the pitch, roll and yaw angles of the aircraft, and the angle of entry into the landing runway, and configured to control the automatic landing of the aircraft.